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PharmaPoint Meningococcal Vaccines

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4.2.3 Exposure is Highest for Those Traveling to the African Meningitis Belt30<br />

4.3 Global Trends 31<br />

4.3.1 US 31<br />

4.3.2 5EU 32<br />

4.3.3 Australia 33<br />

4.3.4 Brazil 33<br />

4.4 Forecast Methodology 34<br />

4.4.1 Sources Used 36<br />

4.4.2 Forecast Assumptions and Methods 39<br />

4.4.3 Sources Not Used 44<br />

4.5 Epidemiology Forecast of <strong>Meningococcal</strong> Disease (2012-2022) 44<br />

4.5.1 Incident Cases of <strong>Meningococcal</strong> Disease 44<br />

4.5.2 Age-Specific Incident Cases of <strong>Meningococcal</strong> Disease 46<br />

4.5.3 Incident Cases of <strong>Meningococcal</strong> Disease by Serogroup 48<br />

4.6 Discussion 50<br />

4.6.1 Conclusions on Epidemiological Trends 50<br />

4.6.2 Limitations of the Analysis 52<br />

4.6.3 Strengths of the Analysis 52<br />

5 Disease Management 53<br />

5.1 <strong>Meningococcal</strong> Immunization Policy 54<br />

5.2 US 56<br />

5.2.1 <strong>Meningococcal</strong> Immunization Recommendations and Policies 56<br />

5.2.2 Clinical Practice 59<br />

5.3 France 61<br />

5.3.1 <strong>Meningococcal</strong> Immunization Recommendations and Policies 61<br />

5.3.2 Clinical Practice 64<br />

5.4 Germany 65<br />

5.4.1 <strong>Meningococcal</strong> Immunization Recommendations and Policies 65<br />

5.4.2 Clinical Practice 66<br />

5.5 Italy 67<br />

5.5.1 <strong>Meningococcal</strong> Immunization Recommendations and Policies 67<br />

5.5.2 Clinical Practice 68<br />

5.6 Spain 69<br />

5.6.1 <strong>Meningococcal</strong> Immunization Recommendations and Policies 69<br />

5.6.2 Clinical Practice 70<br />

5.7 UK 72<br />

5.7.1 <strong>Meningococcal</strong> Immunization Recommendations and Policies 72<br />

5.7.2 Clinical Practice 74<br />

5.8 Japan 75<br />

5.8.1 <strong>Meningococcal</strong> Immunization Recommendations and Policies 75<br />

5.8.2 Clinical Practice 76<br />

5.9 Australia 76<br />

5.9.1 <strong>Meningococcal</strong> Immunization Recommendations and Policies 76<br />

5.9.2 Clinical Practice 78<br />

5.10 Brazil 80<br />

5.10.1 <strong>Meningococcal</strong> Immunization Recommendations and Policies 80<br />

5.10.2 Clinical Practice 81<br />

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