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Safe Handling of Hazardous Drugs

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Environmental<br />

monitoring<br />

Exposure<br />

control plan<br />

Food and<br />

<strong>Drugs</strong> Act<br />

Genotoxic<br />

<strong>Hazardous</strong><br />

drugs<br />

<strong>Hazardous</strong><br />

waste container<br />

High efficiency<br />

particulate air<br />

(HEPA)<br />

ISO Class 7<br />

Luer lock<br />

Mutagenic<br />

Oncogenic<br />

The use <strong>of</strong> analytic techniques to measure contamination <strong>of</strong> an<br />

environment over a period <strong>of</strong> time. In the case <strong>of</strong> hazardous drugs, this is<br />

useful for identifying areas with higher amounts <strong>of</strong> contamination and<br />

determining whether current or introduced controls are effective at<br />

reducing the levels <strong>of</strong> hazardous drugs in the work environment.<br />

A requirement in the Regulation that details how the workplace will<br />

minimize exposure to hazardous drugs. Employers must develop and<br />

implement an exposure control plan if their workers may be exposed to<br />

cytotoxic drugs.<br />

Canadian federal legislation that regulates the use <strong>of</strong> cosmetics, drugs, and<br />

food. Substances under this act are not required to provide supplier labels<br />

and SDSs as described in WHMIS.<br />

A substance that can damage the genetic material <strong>of</strong> cells, which causes<br />

mutations to arise.<br />

As defined by NIOSH, a group <strong>of</strong> drugs that have know carcinogenicity,<br />

teratogenicity, reproductive toxicity, organ toxicity, or genotoxicity in<br />

humans or animals (or a new drug that mimics an existing drug with one <strong>of</strong><br />

these characteristics). Examples include drugs used for treatment <strong>of</strong><br />

cancer, hormone treatments, and diluted forms <strong>of</strong> these drugs used to<br />

treat a range <strong>of</strong> illnesses.<br />

A container that is designated to be used only for hazardous waste. These<br />

must be clearly labelled as meant for hazardous waste and are generally a<br />

different colour than other waste containers in the workplace so that they<br />

can be easily identified.<br />

A specialized filter that traps particulate matter. They are used to filter air<br />

that is entering a biological safety cabinet as well as air that is exhausted<br />

externally. They may also be used in local ventilation systems for specific<br />

rooms in a workplace.<br />

A measure <strong>of</strong> air quality using the ISO classification system, which is based<br />

on how much particulate is present per cubic metre <strong>of</strong> air. The classes go<br />

from what is considered the “dirtiest” air (ISO Class 9) to what is the<br />

“cleanest” air (ISO Class 1).<br />

A fitting for medical instruments that is designed to prevent leaking.<br />

A substance that causes mutations to occur in the genetic material <strong>of</strong> cells.<br />

Describes a substance that has the ability to cause a (malignant) cancer.<br />

Best Practices for the <strong>Safe</strong> <strong>Handling</strong> <strong>of</strong> <strong>Hazardous</strong> <strong>Drugs</strong> 61

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