CPDD 78th Annual Scientific Meeting Program

June 12, 2016 Fiesta
Sunday, June 12, 2016
Oral Communications 1 Sunday,
RUSH: STIMULANTS-PRECLINICAL STUDIES
12
3:00 - 5:00 PM
Chairs: Wendy J. Lynch and Jae K. Kim
3:00 Effect of a dopamine D3 receptor partial agonist on cocaine-induced locomotion and
self-administration
J. Bonadonna 1 , G. Powell 1 , A. K. Carlson 1 , R. Mendoza 1 , R. H. Mach 2 , R. R. Luedtke 3 ,
J. L. Neisewander 1 , 1 School of Life Sciences, Arizona State University, Tempe, AZ, 2 Perelman
School of Medicine, University of Pennsylvania, Philadelphia, PA, 3 Health Science Center,
University of North Texas, Fort Worth, TX
3:15 CXCR4 antagonist Plerixafor attenuates cue-and cue/drug-induced relapse to cocaine seeking
and expression and development of cocaine-induced conditioned place preference
J. K. Kim 1 , S. Rawls 1,2 , 1 Pharmacology, Lewis Katz School of Medicine at Temple University,
Philadelphia, PA, 2 Center for Substance Abuse Research, Lewis Katz School of Medicine at
Temple University, Philadelphia, PA
3:30 Kappa opioid receptor agonist 16-ethynyl salvinorin A attenuates the rewarding effects of
cocaine in the progressive ratio model in rats with fewer side-effects
B. M. Kivell 1 , D. Young 1 , A. Culverhouse 1 , T. Prisinzano 2 , 1 School of Biological Sciences,
Victoria University of Wellington, Wellington, New Zealand, 2 Department of Medicinal
Chemistry, University of Kansas, Lawrence, KS
3:45 Effects of chronic amphetamine on abuse-related behavioral and neurochemical effects of
cocaine in rats
A. Johnson, S. S. Negus, Virginia Commonwealth University, Richmond, VA
4:00 Long-term blockade of cocaine use and locomotor activation in rats by an adenoviral vectordelivered
cocaine hydrolase
J. R. Smethells 2 , N. Swalve 2 , S. Brimijoin 1 , R. Parks 4 , M. E. Carroll 2 , 1 Molecular
Pharmacology, Mayo Clinic, Rochester, MN, 2 University of Minnesota, St. Paul, MN, 4 Ottawa
Hospital Research Institute, Ottawa, ON, Canada
4:15 Exercise during early, but not late, abstinence attenuates subsequent relapse vulnerability in a
rat model
W. J. Lynch, R. M. Beiter, A. B. Peterson, J. Abel, Psychiatry and Neurobehavioral Sciences,
University of Virginia, Charlottesville, VA
4:30 New generation tamoxifen analogs as potential treatments for amphetamine abuse
C. A. Carpenter 1 , R. Altshuler 1 , A. Zestos 2 , R. Sorenson 3 , E. M. Jutkiewicz 1 , R. Kennedy 2 ,
H. Showalter 3 , M. Gnegy 1 , 1 Pharmacology, University of Michigan, Ann Arbor, MI,
2
Chemistry, University of Michigan, Ann Arbor, MI, 3 Vahlteich Medicinal Chemistry Core,
University of Michigan, Ann Arbor, MI
4:45 Enantiomers of (±)GZ-888 potently and selectively inhibit vesicular monoamine transporter-2
function and methamphetamine-stimulated locomotor activity
N. Lee 1 , G. Zheng 3 , S. M. Mayfield 2 , E. D. Denehy 2 , J. R. Nickell 1 , Z. Cao 1 , P. A. Crooks 3 ,
M. T. Bardo 2 , L. P. Dwoskin 1 , 1 Pharmaceutical Sciences, University of Kentucky,
Lexington, KY, 2 Psychology, University of Kentucky, Lexington, KY, 3 Pharmaceutical
Sciences, University of Arkansas for Medical Sciences, Fayetteville, AR
3