Global Proteomics Market Analysis

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Market Analysis Growing need for automated crystallization shaping the protein crystallography market • Increasing demand for high throughput protein crystallography has resulted increase in adoption of automated crystallization. The need to understand exactly how small molecules bind to their protein target is driving the demand for protein crystallography in drug discovery. A higher throughput protein crystallography process requires protein crystallization to also become high throughput and this is best achieved through automated crystallization. A number of large proteomic initiatives are being launched, increasing market opportunities for automated crystallization. • Drug discovery initiatives have driven numerous technological advancements in structural proteomics. Pharmaceutical companies today acknowledge that structure discovery helps lead optimization. With rapid technology advances, structure-based design is set to become a preferred method for discovering new drugs. • As an increasing number of companies discover the importance and significance of protein structure studies for drug discovery, more efforts are being made toward improving structural determination technologies. Market consolidation and industrialization along with the introduction of powerful integrated systems is changing research approaches. Besides automation, miniaturization of protein crystals and processes including purification is another big trend. • Lack of experienced researchers has further fueled the demand for automated crystallization. Protein crystallization is a process that requires training, skill, and time. The number of trained researchers and people willing to commit to such a process has been decreasing. The surge in automation has addressed the worrisome dearth of protein-structure researchers. However, automation allows researchers with less experience and training to be involved in crystallization. This frees researchers, allowing them to focus on increasing productivity, reproducibility, and throughput. www.merkleandsears.com C a p a c i t y Steep growth curve ahead for the market Current market position xx% xx% 2016 Market share breakdown, 2015 Predicted strategic inflection point xx% 6 Time
Industry Analysis Global Industry Overview • Proteomic research inherently requires huge capital investments and historically, it has yielded poor revenues. Pharmaceutical companies have hesitated in adopting the proteomics technologies in their drug development pipeline as they have been wary of premium pricing. • However, today public funding institutions are giving importance to this growing biological discipline next to comparative genomics. The proteomics market is considered an emerging area with immense potential. In fact, Governments and federal ministries in three major European countries, namely the United Kingdom, France and Germany, have allocated thematic priorities to nurture the growth of this market. This has resulted in greater industrialization of this field, which in turn, has boosted the confidence of companies to invest in this fast-paced and dynamic arena. Low return on investment that can dissuade potential entrants in proteomics technology markets has thus been offset by increasing public funding. • The increasing relevance of protein-protein interactions and protein analytics in drug discovery as well as clinical diagnostics has highlighted the importance of proteome research. Technological advancements in protein separation technologies and two-dimensional gel electrophoresis are likely to usher in a ubiquitous approach to assess differential protein expressions. Maximum utility of expression proteomics tools in the target discovery phase of drug development is likely to trigger reliable separation and identification of low abundant proteins with poor expression levels. Moreover, the development of matrix-assisted laser desorption/ionization (MALDI) and electrospray ionization (ESI) technologies has enlarged the scope of building versatile mass spectrometers, considered the cornerstone of proteomics. The improved mass spectrometers are likely to have enhanced functionalities of automation and compatibility with other proteomics equipment. www.merkleandsears.com Global proteomics market $ Million 2014 2015 2016 2017 2018 2019 2020 Market share breakdown, 2015 xx% xx% xx% 7
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Global Proteomics Market Analysis

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