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Global Active Pharmaceutical Ingredients (API) Market

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<strong>Global</strong> <strong>Active</strong> <strong>Pharmaceutical</strong> <strong>Ingredients</strong> (<strong>API</strong>) <strong>Market</strong>, 2014 - 2020<br />

development program for biologics is less as compared to chemical <strong>API</strong>s, primarily because of high<br />

success rates in the pipeline phase. This factor has attracted higher investments in the biologics and<br />

biosimilars market.<br />

Apart from the currently marketed blockbuster biologics such as Humira and Herceptin, several other<br />

promising biologics such as mepolizumab (GSK), dupilumab (Sanofi/Regeron), alirocumab (Sanofi),<br />

evolocumab (Amgen), brodalumab (Amgen), ixekizumab (Eli Lilly) and secukinumab (Novartis) are<br />

expected to enter different geographical markets during the forecast period from 2015 to 2020. Presently,<br />

most of the biologics are manufactured in-house due to intellectual property concerns and quality issues.<br />

However, the manufacturing of biological <strong>API</strong>s is a very complex and challenging process. Hence,<br />

innovator companies are outsourcing to contract manufacturing companies with biological production<br />

expertise.<br />

Teva <strong>Pharmaceutical</strong> Industries Ltd dominated active pharmaceutical ingredients market in 2014. Major<br />

factors attributed to its dominance are broad product portfolio and high market penetration. Zhejiang<br />

Medicine Co., Ltd. and Zhejiang NHU Co., Ltd secured the second market position in 2015. North China<br />

<strong>Pharmaceutical</strong> Group Corp. (NCPC) and Northeast <strong>Pharmaceutical</strong> Group Co., Ltd. held the third<br />

position in 2015. Other players in the active pharmaceutical ingredients market include Dr.Reddy's<br />

Laboratories Limited, Sandoz (Novartis AG), Aurobindo Pharma Limited, Zhejiang Hisun <strong>Pharmaceutical</strong><br />

Co., Ltd. and Zhejiang Huahai <strong>Pharmaceutical</strong>s Co., Ltd. and others<br />

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