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The Placebo Effect in Marketing - Zicklin School of Business

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408 JOURNAL OF MARKETING RESEARCH, NOVEMBER 2005<br />

dependent measure. <strong>The</strong> first was a 2 (dr<strong>in</strong>k consumed:<br />

energy dr<strong>in</strong>k versus placebo) × 2 (motivation: high versus<br />

low) analysis <strong>of</strong> variance, with expectations as a covariate<br />

<strong>in</strong> the analysis. Expectations, both as a cont<strong>in</strong>uous variable<br />

and as a median split, did not <strong>in</strong>teract either with dr<strong>in</strong>k consumed<br />

or with motivation, but it did account for significant<br />

error variance <strong>in</strong> several cases; thus, we <strong>in</strong>cluded it as a<br />

cont<strong>in</strong>uous covariate <strong>in</strong> each analysis <strong>of</strong> variance. In addition,<br />

for each dependent variable we ran a series <strong>of</strong> planned<br />

contrasts between each <strong>of</strong> the four treatment conditions and<br />

the hang<strong>in</strong>g control (energy dr<strong>in</strong>k/high motivation, energy<br />

dr<strong>in</strong>k/low motivation, placebo/high motivation, placebo/low<br />

motivation, and control). Because the pattern replicates<br />

across the dependent variables, we discuss only the diastolic<br />

blood pressure analyses <strong>in</strong> depth (see Figure 1).<br />

As we hypothesized, motivation plays a key role <strong>in</strong><br />

chang<strong>in</strong>g response to a brand placebo at a physiological<br />

level. We observed a significant two-way <strong>in</strong>teraction<br />

between dr<strong>in</strong>k consumed and motivation (F(1, 62) = 4.49,<br />

p < .05). This <strong>in</strong>teraction can be best <strong>in</strong>terpreted by exam<strong>in</strong><strong>in</strong>g<br />

the mean change <strong>in</strong> diastolic blood pressure for the four<br />

treatment conditions versus the control condition. 2 When<br />

participants consumed an actual energy dr<strong>in</strong>k, we observed<br />

a significant <strong>in</strong>crease <strong>in</strong> their diastolic blood pressure compared<br />

with the control group that consumed water, regardless<br />

<strong>of</strong> the participants’ motivation level. Participants <strong>in</strong> the<br />

energy dr<strong>in</strong>k/high-motivation condition had a mean change<br />

<strong>in</strong> diastolic blood pressure <strong>of</strong> .04 mmHg (log normalized)<br />

and participants <strong>in</strong> the energy dr<strong>in</strong>k/low-motivation condition<br />

had a mean change <strong>of</strong> .04 mmHg versus control<br />

2<strong>The</strong> results do not change mean<strong>in</strong>gfully if the data are analyzed us<strong>in</strong>g<br />

blood pressure after beverage consumption as the dependent variable and<br />

blood pressure before beverage consumption as a covariate <strong>in</strong> the analyses;<br />

similarly, we observe no mean<strong>in</strong>gful changes for parallel analyses on the<br />

other dependent variables.<br />

Change <strong>in</strong> Diastolic Blood Pressure<br />

Figure 1<br />

PLACEBO EFFECTS ON DIASTOLIC BLOOD PRESSURE<br />

.12<br />

.10<br />

.08<br />

.06<br />

.04<br />

.02<br />

0<br />

–.02<br />

–.04<br />

–.06<br />

–.08<br />

–.10<br />

–.12<br />

Energy dr<strong>in</strong>k <strong>Placebo</strong> Control<br />

Low motivation<br />

High motivation<br />

Control/no motivation<br />

participants (–.06 mmHg, F(1, 91) = 5.39, p < .05, and<br />

F(1, 91) = 4.10, p < .05, respectively). In contrast, participants<br />

<strong>in</strong> the placebo conditions had very different results by<br />

motivation level. Participants <strong>in</strong> the placebo/low-motivation<br />

condition (mean change = –.07 mmHg) were no different<br />

from participants <strong>in</strong> the control condition (–.06 mmHg,<br />

F(1, 91) = .09, p = .77). Participants <strong>in</strong> the placebo/highmotivation<br />

condition (mean change = .09 mmHg) showed<br />

significantly greater <strong>in</strong>creases <strong>in</strong> diastolic blood pressure<br />

than participants <strong>in</strong> the control condition (–.06 mmHg,<br />

F(1, 91) = 9.61, p < .01) and, though directionally higher,<br />

were not statistically separable from either energy dr<strong>in</strong>k<br />

motivation condition (both ps > .30). This pattern <strong>of</strong> results<br />

holds for systolic blood pressure, physical reflex tasks,<br />

mental alertness, and subjective arousal (see Table 1).<br />

DISCUSSION<br />

Taken together, our study results and SCA’s study results<br />

provide compell<strong>in</strong>g evidence that market<strong>in</strong>g activities can<br />

lead to substantial placebo effects. As <strong>in</strong> SCA’s research, the<br />

placebo effect that we observed led to changes <strong>in</strong> the participants’<br />

experience with the efficacy <strong>of</strong> the product. <strong>The</strong><br />

placebo energy dr<strong>in</strong>k was capable <strong>of</strong> rais<strong>in</strong>g blood pressure,<br />

<strong>in</strong>creas<strong>in</strong>g physical reflexes, enhanc<strong>in</strong>g mental alertness, and<br />

rais<strong>in</strong>g the self-reported arousal level for the participants.<br />

Notably, these placebo effects were only observed for highly<br />

motivated participants. When participants reported a high<br />

degree <strong>of</strong> desire for the <strong>in</strong>creased energetic boost from an<br />

energy dr<strong>in</strong>k, we found that the placebo beverage led to the<br />

same levels <strong>of</strong> performance and physiological change that an<br />

actual energy dr<strong>in</strong>k conta<strong>in</strong><strong>in</strong>g caffe<strong>in</strong>e and taur<strong>in</strong>e provided.<br />

However, when participants had low levels <strong>of</strong> motivation,<br />

consumption <strong>of</strong> the energy beverage led to the same effects as<br />

a glass <strong>of</strong> water. In addition to the important role that expectations<br />

play <strong>in</strong> market<strong>in</strong>g placebo effects, these data suggest<br />

that motivation also plays an important role. It is possible <strong>in</strong><br />

some situations that these two constructs <strong>in</strong>teract <strong>in</strong> <strong>in</strong>terest<strong>in</strong>g<br />

ways. For example, <strong>in</strong> some situations, highly motivated<br />

people might change their expectations, thus lead<strong>in</strong>g to a<br />

placebo effect. However, our data do not support such a mediat<strong>in</strong>g<br />

role <strong>in</strong> the scenario we <strong>in</strong>vestigated. Our <strong>in</strong>vestigation<br />

suggests that sometimes consumers do not necessarily have<br />

to expect a product to work, they just have to want it to work.<br />

Although the medical literature reveals that the focus <strong>of</strong><br />

<strong>in</strong>vestigations is on positive or beneficial effects <strong>of</strong> placebos,<br />

SCA clearly demonstrate that there can be substantial negative<br />

effects <strong>of</strong> placebos <strong>in</strong> market<strong>in</strong>g contexts. <strong>The</strong> physiological<br />

placebo effects we observe <strong>in</strong> this study also suggest that<br />

caution should be taken when mak<strong>in</strong>g claims about products<br />

that seem harmless. We carefully screened participants who<br />

could be harmed by <strong>in</strong>creases <strong>in</strong> blood pressure <strong>in</strong> this study,<br />

but nosuch screen<strong>in</strong>g would occur <strong>in</strong> the marketplace.<br />

An <strong>in</strong>terest<strong>in</strong>g aspect <strong>of</strong> SCA’s work is the demonstration<br />

that market<strong>in</strong>g placebo effects can occur largely nonconsciously.<br />

Whereas the motivation that drove the placebo<br />

effect we observed <strong>in</strong> our study was conscious, it seems<br />

highly likely that the mechanism through which it operated<br />

may also have been nonconscious. Further work <strong>in</strong> this<br />

doma<strong>in</strong> should prove extremely <strong>in</strong>terest<strong>in</strong>g both to marketers<br />

and to public policy makers. Once aga<strong>in</strong>, we f<strong>in</strong>d that<br />

seem<strong>in</strong>gly <strong>in</strong>nocuous market<strong>in</strong>g activities do far more than<br />

meets the eye.

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