Osteoporosis
AACE_Osteoporosis_Decision_Aid_B
AACE_Osteoporosis_Decision_Aid_B
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Medication Options<br />
Medication How it Works How it is Given Side Effects Efficacy<br />
Alendronate<br />
(Fosamax)<br />
Decreases bone<br />
breakdown<br />
1 pill once weekly<br />
30 minutes before breakfast<br />
Heartburn, stomach<br />
pain, bone and joint<br />
pains<br />
Risedronate<br />
(Actonel,<br />
Atelvia)<br />
Decreases bone<br />
breakdown<br />
1 pill once weekly 30 minutes before<br />
breakfast (Actonel), after breakfast<br />
(Atelvia) or once monthly 1 hour<br />
before breakfast (Actonel)<br />
Heartburn, stomach<br />
pain, bone and joint<br />
pains<br />
Ibandronate<br />
(Boniva)<br />
Decreases bone<br />
breakdown<br />
1 pill once monthly 1 hour before<br />
breakfast<br />
Heart burn, stomach<br />
pain, bone and joint<br />
pains<br />
Zoledronic acid<br />
(Reclast)<br />
Decreases bone<br />
breakdown<br />
Intravenous (IV)<br />
infusion once yearly<br />
Bone and joint<br />
pains<br />
Denosumab<br />
(Prolia)<br />
Decreases bone<br />
breakdown<br />
Subcutaneous<br />
injection (shot)<br />
every 6 months<br />
Bone and joint<br />
pains<br />
Raloxifene<br />
(Evista)<br />
Decreases bone<br />
breakdown<br />
1 pill daily Hot flashes, rare<br />
blood clots<br />
Calcitonin<br />
(Miacalcin)<br />
Decreases bone<br />
breakdown<br />
Nasal spray daily<br />
Nasal irritation<br />
Teriparatide<br />
(Forteo)<br />
Increases bone<br />
formation<br />
Injections using pen device daily<br />
Injection site<br />
reaction, leg cramps<br />
Efficacy:<br />
is the most efficacious in decreasing fracture risk
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