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International Seminars in Surgical Oncology 2008, 5:19 http://www.issoonline.com/content/5/1/19<br />

Microscopic findings <strong>of</strong> the resected specimen<br />

Figure 6<br />

Microscopic findings <strong>of</strong> the resected specimen. Histologically, the <strong>tumor</strong> mainly consisted <strong>of</strong> spindle cells, which showed<br />

fascicular growth. Immunostaining demonstrated c-kit positive, partial α-SMA positive, and S-100 protein negative.<br />

uted towards conception, design, analysis and<br />

interpretation <strong>of</strong> data. TN Contributed towards conception,<br />

acquisition <strong>of</strong> data and preparation <strong>of</strong> the draft. TJ<br />

Contributed towards revising the final manuscript critically.<br />

All authors read and approved the final manuscript.<br />

Acknowledgements<br />

The written consent was obtained from the patient.<br />

References<br />

1. DeMatteo RP, Lewis JJ, Leung D, Mudan SS, Woodruff JM, Brennan<br />

MF: Two hundred <strong>gastrointestinal</strong> <strong>stromal</strong> <strong>tumor</strong>s recurrence<br />

pattern and prognostic factor for survival. Ann Surg<br />

2000, 231:51-8.<br />

2. Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishiguro S,<br />

Kawano K, Hamada M, Kurata A, Takeda M, Tunio Ghulam Muhammad,<br />

Matsuzawa Y, Kanakura Y, Hinomura Y, Kitamura Y: Gain-<strong>of</strong>function<br />

mutation <strong>of</strong> c-kit gene and molecular target therapy<br />

in GISTs. Nippon Shokakibyo Gakkai Zasshi (Jpn J Gastroenterol)<br />

2003, 100:13-20.<br />

3. Miettinen M, Monihan JM, Sarlomo-Rikala M, Kovatich AJ, Carr NJ,<br />

Emory TS, Sobin LH: Gastrointestinal <strong>stromal</strong> <strong>tumor</strong>s/smooth<br />

muscle <strong>tumor</strong>s (GISTs) primary in the omentum and<br />

mesentery: clinicopathologic and immunohistochemical<br />

study <strong>of</strong> 26 <strong>case</strong>s. Am J Surg Pathol 1999, 23:1109-18.<br />

4. Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishiguro S,<br />

Kawano K, Hanada M, Kurata A, Takeda M, Muhammad Tunio G,<br />

Matsuzawa Y, Kanakura Y, Shinomura Y, Kitamura Y: Gain-<strong>of</strong>-functionfmutations<br />

<strong>of</strong> c-kit in human <strong>gastrointestinal</strong> <strong>stromal</strong><br />

<strong>tumor</strong>s. science 1998, 279:577-80.<br />

5. Sakurai S, Hishima T, Takazawa Y, Sano T, Nakajima T, Saito K,<br />

Morinaga S, Fukayama M: Gastrointestinal <strong>stromal</strong> <strong>tumor</strong>s and<br />

KIT-positive mesenchymal cells in the omentum. Pathol Int<br />

2001, 51:524-31.<br />

6. Shingu Y, Terasaki M, Okamoto Y, Goto Y, Kurumiya Y, Natsume S:<br />

A <strong>case</strong> <strong>of</strong> <strong>gastrointestinal</strong> <strong>stromal</strong> <strong>tumor</strong>(GIST) <strong>of</strong> the<br />

omentum. Journal <strong>of</strong> Japan Surgical association 2003, 64:1246-50.<br />

Page 5 <strong>of</strong> 5<br />

(page number not for citation purposes)

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