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IFU:​ ​Type 1 diabetes mellitus<br />

Route: By injection<br />

Dosage: U-100<br />

Action: lowers blood glucose by stimulating peripheral glucose uptake by skeletal muscle and<br />

fat, and by inhibiting hepatic glucose production.<br />

Adverse​ ​Reaction: Itching, skin rash, wheezing, trouble breathing, fast heart rate, and sweating.<br />

Interactions: Gatifloxacin, tequin, and tequin teqpaq.<br />

Januvia​(Sitagliptin)<br />

Pronunciation: Sit-a-glip-tin<br />

Classification:​ DPP-4 inhibitor​<br />

IFU:​ ​Type 2 diabetes mellitus<br />

Route: Orally<br />

Dosage: 25 mg, 50 mg, and 100 mg.<br />

Action:​ Inhibits the enzyme dipeptidyl peptidase-4 (DPP-4), which slows the inactivation of<br />

incretin hormones, resulting in increased levels of active incretin hormones.<br />

Adverse​ ​Reaction: Headache, pancreatitis, nausea, diarrhea, etc.<br />

Interactions:​ Insulin, glyburide, glipizide, and glimepiride.<br />

Lantus​(Insulin Glargine)<br />

Pronunciation: Glar-gen<br />

Classification:​ insulin​ ​<br />

IFU:​ ​Type 1 diabetes mellitus<br />

Route: By injection<br />

Dosage: 100 units/ml<br />

Action: ​Promotes glucose transport, which stimulates carbohydrate metabolism in skeletal and<br />

cardiac muscle and adipose tissue.<br />

Adverse​ ​Reaction​: urticaria, rash, pruritus, redness, stinging, or warmth at injection site.<br />

Interactions: ​Acetazolamide, albuterol, antiretrovirals, asparaginase, calcitonin, etc.<br />

NovoLog​(Insulin aspart)<br />

Pronunciation: in-su-lin as-spart<br />

Classification:​ ​ insulin<br />

IFU: ​Type 1 diabetes mellitus​<br />

Route: By injection<br />

Dosage: 100 units/ml<br />

Action: Lowers blood glucose by stimulating glucose uptake in skeletal muscle and fat, and<br />

inhibiting hepatic glucose production.<br />

Adverse​ ​Reaction: lipodystrophy, pruritus, erythema, swelling.

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