Epigenomics AG - Corporate Presentation - July 2015
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Possible Performance Improvement (post-hoc analysis 1,2 )<br />
+ + +<br />
- + +<br />
positive (+)<br />
(3% of all cases)<br />
re-test with FIT:<br />
65% sensitivity<br />
96% specificity<br />
overall combined performance 1<br />
- - +<br />
- - -<br />
“1 out of 3“<br />
or “weak” positives<br />
(15% of all cases)<br />
negative (-)<br />
(82% of all cases)<br />
re-test<br />
re-test with Epi proColon:<br />
70% sensitivity<br />
90% specificity<br />
overall combined performance 2<br />
1<br />
Based on post-hoc analysis of FIT/Sept9 comparison study 2 Based on post-hoc analysis of FIT/Sept9 comparison study and retesting of „weak positive“ results with Epi proColon®<br />
34 | <strong>July</strong> <strong>2015</strong>