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Epigenomics AG - Corporate Presentation - July 2015

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Possible Performance Improvement (post-hoc analysis 1,2 )<br />

+ + +<br />

- + +<br />

positive (+)<br />

(3% of all cases)<br />

re-test with FIT:<br />

65% sensitivity<br />

96% specificity<br />

overall combined performance 1<br />

- - +<br />

- - -<br />

“1 out of 3“<br />

or “weak” positives<br />

(15% of all cases)<br />

negative (-)<br />

(82% of all cases)<br />

re-test<br />

re-test with Epi proColon:<br />

70% sensitivity<br />

90% specificity<br />

overall combined performance 2<br />

1<br />

Based on post-hoc analysis of FIT/Sept9 comparison study 2 Based on post-hoc analysis of FIT/Sept9 comparison study and retesting of „weak positive“ results with Epi proColon®<br />

34 | <strong>July</strong> <strong>2015</strong>

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