Obeticholic acid used to treat primary biliary cholangitis
Obeticholic acid (abbreviated to OCA, trade name Ocaliva), is a semi-synthetic bile acid analogue which has the chemical structure 6α-ethyl-chenodeoxycholic acid. It is used as a drug to treat primary biliary cholangitis, and is undergoing development for several other liver diseases and related disorders. Visit: http://www.aasraw.com/products/obeticholic-acid-powder/
Obeticholic acid (abbreviated to OCA, trade name Ocaliva), is a semi-synthetic bile acid analogue which has the chemical structure 6α-ethyl-chenodeoxycholic acid. It is used as a drug to treat primary biliary cholangitis, and is undergoing development for several other liver diseases and related disorders. Visit: http://www.aasraw.com/products/obeticholic-acid-powder/
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Cholic<br />
Acid<br />
81-25-4 C24-H40-O5<br />
7.<strong>Obeticholic</strong> <strong>acid</strong> overview<br />
<strong>Obeticholic</strong> <strong>acid</strong> (OCA) is a synthetically modified bile <strong>acid</strong> and potent agonist of the<br />
farnesoid X nuclear recep<strong>to</strong>r (FXR) that is <strong>used</strong> <strong>to</strong> <strong>treat</strong> liver diseases including <strong>primary</strong><br />
<strong>biliary</strong> <strong>cholangitis</strong>. <strong>Obeticholic</strong> <strong>acid</strong> has not been linked <strong>to</strong> elevations in serum enzyme<br />
levels during therapy, but has been linked <strong>to</strong> an increased rate of severe liver related<br />
adverse events such as ascites, jaundice and liver failure.<br />
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