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<strong>Dialysis</strong> & Apheresis for Africa<br />

Overview<br />

July 2018<br />

Statement of Confidentiality<br />

The information in this document contains trade secrets and commercial information that are proprietary or confidential and may not be<br />

disclosed unless such disclosure is required by federal or state law or regulations. In any event, persons to whom the information is disclosed<br />

must be informed that the information is proprietary or confidential and may not be further disclosed by them, and you will be responsible for any<br />

violation of these restrictions by your employees, contractors or agents. These restrictions on disclosure will apply equally to all future<br />

information supplied to you in connection <strong>with</strong> this presentation which is indicated as proprietary or confidential.<br />

1


Presentation Overview<br />

• African market overview<br />

• Who are we?<br />

• Core Team<br />

• Initial investment<br />

• Return on Investment<br />

• Timelines<br />

• References<br />

2


African Market Overview<br />

• <strong>Dialysis</strong> Product Market Focus Groups<br />

• 4 out of 5 adults have Diabetes, Hypertension or a combination of<br />

• Both diseases are leading causes of renal failure in adults 40 years<br />

or older that will need some form of dialysis life-saving intervention<br />

• Other Populations in Need in <strong>Dialysis</strong><br />

• Emergency Traumatic Situations caused by accidents<br />

• Pediatric populations<br />

• Sickled Cell<br />

• Lupus<br />

• Pyelonephritis<br />

• Polycystic Kidney Diseases<br />

• HIV


African Market Overview<br />

• Apheresis product Market Focus Groups<br />

• WHO and the UN cited 90% of the world’s Sickle<br />

Cell population resides in Nigeria, Democratic<br />

Republic of Congo and India<br />

• Other Diseases that Apheresis will manage in<br />

this market:<br />

• HELLP SYNDROME- a major cause for mortality in<br />

pregnant women<br />

• Myastenia Gravis<br />

• Leukocytosis<br />

• Thrombotic Thrombocytopenic purpura<br />

• Hemodialysis<br />

• Peritoneal <strong>Dialysis</strong><br />

• Continuous Renal Replacement Therapy (CCRRT)<br />

• Apheresis machine <strong>with</strong> utilization<br />

of existing Hemodialysis machines


<strong>Dialysis</strong> Treatment in Africa<br />

• <strong>Dialysis</strong> treatment rate is 85%)<br />

• Majority (~70%) of patients that are fortunate to get treatment are<br />

underdialyzed<br />

• Inadequate expertise (Brain drain)<br />

• Most pursing for transplants which is also mostly absent<br />

• Most that can afford travel to US, UK and India<br />

Journal of the International Society for Peritoneal <strong>Dialysis</strong> 30 1 (2010): 23-8.<br />

Kidney International Supplements (2013) 3, 161–163; doi:10.1038/kisup.2013.4<br />

5


WE ARE <strong>COBALT</strong> UNITED!<br />

OUR VISION IS TO MEET HEALTHCARE NEEDS BY BECOMING THE LEADING<br />

HEALTHCARE PROVIDER IN AFRICA.<br />

• Unique experience <strong>with</strong> unparallelled team to operationalize every aspect of dialysis<br />

across the continent <strong>with</strong> speed and excellence<br />

• 20+ years’ experience operationalizing projects in Africa<br />

• It takes a global leader to deliver patient centered solutions around the world.<br />

• UN Sustainable Development Goals<br />

identifies 17 Development Goals to<br />

transform our world by 2030.<br />

• We are prepared to address Goal 3, which<br />

is “to ensure healthy lives and promote wellbeing<br />

for all at all ages.”<br />

Who are we?


What are we offering<br />

• Reduce mortality rate by bringing <strong>Dialysis</strong> treatment to<br />

the people (up 3000 in/out patient centers by year 5 in<br />

Africa)<br />

• Have 95% of the Market share in Africa by year five<br />

• Provide training centers to train the highly qualified<br />

personnel<br />

• Provide value proposition through high quality of care.<br />

7


Expected Timeline & ROI<br />

Centers Nurses Biomeds<br />

# of<br />

Countries Expenses ROI Profit Margins<br />

*1-3month 5 50 3 1 1.5 Mil N/A<br />

4-12 month 95 950 3 3 7.0Mil 40 Mil (12 Mil - 65 Mil) 30 Mil (2 Mil - 55 Mil)<br />

Year 1 total 100 1000 6 4 8.5 Mil 40 Mil (12 Mil - 65 Mil) 30 Mil (2 Mil - 55 Mil)<br />

Year 2 1000 10,000 50 35 100 Mil 400 Mil (120 Mil - 650 Mil) 300 Mil (20 Mil - 550 MIl)<br />

Year 3-5 3000 30,000 150 35 300 Mil 1.2 BIL (360 Mil - 1.95 BIL) 900 Mil (60 Mil - 1.65 BIL)<br />

* Approx 1.0 years to break even (based on median profits)<br />

• Project breaks even and turns profit by year 1<br />

• Start-up costs: 4.8M to mobilize team and training<br />

across 5 initial countries + 8.5M project related costs<br />

over a period of a year = $13.3M<br />

• Target raise = $50M to cover 3 years’ operating<br />

expenses. To be paid in milestones over 3 years.


Select Cobalt <strong>Dialysis</strong> Team Members


Core Clinical Leadership Team<br />

• Dr. Felix Boakye-Aygeman, MD, PhD, Chief Medical Officer<br />

• Hannan Jarsa Karnley-Bestman, RN, BSN, <strong>Dialysis</strong> Program<br />

Director<br />

• Emily Njoroge- RN, BSN, <strong>Dialysis</strong> nurse and Program Manager<br />

• Mark Mrithiringi, RN BSN, <strong>Dialysis</strong> Nurse<br />

• Kenneth Tapley- Certified Biomed Technician<br />

• Calvin Posley, RN, BSN, MSN, <strong>Dialysis</strong> nurse<br />

• Mary Sellars, PCT,CCHT, <strong>Dialysis</strong> Technician


African Market Overview<br />

• Why Invest in Specialty HealthCare in Africa Now?<br />

According to a recent Washington Post (June 9, 2018) Article:<br />

• The Future is African<br />

• Since 2000, at least half of the countries in the World <strong>with</strong> the highest<br />

growth rates have been in Africa<br />

• By 2030, 43 Percent of Africans are projected to join the Global Upper &<br />

Middleclass<br />

• By 2030, African Household Consumption expectation will be at 2.5<br />

Trillion<br />

• With Combined Consumer & Business Spending at 6.7 Trillion<br />

• The Human Factor- 1 in 4 humans will be African by 2050<br />

• By the end of the Century, 40 Percent of the World’s Population will be<br />

African


Way Forward<br />

Richard insert


References<br />

Booker,Salih and Rickman,Ari. (2018,June 9). The future is African- and the United States is not<br />

prepared. Retrieved from https://www.washingtonpost.com/news/democracypost/wp/2018/06/09/the-future-is-african-and-the-united-states-is-notprepared/?noredirect=on&utm_term=.715f541ad3fd<br />

DeBaun,Michael R. MD, MPH<br />

Galadanci,Najibah A. MBBS. (2018,April 23).<br />

Sickle cell disease in sub-Saharan Africa<br />

Journal of the International Society for Peritoneal <strong>Dialysis</strong> 30 1 (2010): 23-8.<br />

Kidney International Supplements (2013) 3, 161–163; doi:10.1038/kisup.2013.4<br />

Retrieved from https://www.uptodate.com/contents/sickle-cell-disease-in-sub-saharan-africa<br />

Retrieved from https://www.propublica.org/article/dialysis-south-africa<br />

Waiting list for dialysis in South Africa:<br />

Retrieved from https://www.health-e.org.za/2015/03/12/thousands-may-die-<strong>with</strong>out-life-savingdialysis

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