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OVGU_Stimulate_Broschuere_EN

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Another milestone is a novel intuitive instrument tracking method. After all, the instruments are to<br />

be safely navigated through the human body and precisely positioned at their target point. “Our<br />

idea is a tracking system with optical Moiré Phase markers”, says the scientist, who explains: "The<br />

Moiré patterns can be compared with lenticular images. They change their appearance with minimal<br />

rotation. The position and orientation of the markers can be measured by a camera inside the<br />

MRI gantry and used to control the MRI image acquisition. When the needle is moved, for example,<br />

through the patient's breathing, the imaging plane follows the movement."<br />

The ablation probes, which are used for the novel local heat therapy of the liver tumor, are to<br />

be guided in this manner. During heat therapy, microwaves heat the tumour from the inside. The<br />

problem: the blood in the blood vessels transports the heat away from the tumour, so that it partially<br />

cools down again.<br />

“The ablation needle can only measure the temperature at its tip. In order to achieve complete<br />

thermometry during the procedure, we would like to use the MRI device itself as a temperature<br />

measuring device," says Dr. Urte Kägebein, naming another milestone. To take the liver as an<br />

example: MRI technology offers a unique opportunity to measure physical parameters such as the<br />

elasticity of liver tissue or temperature distribution. With the help of software developed in-house,<br />

this information would merge with that of the ablation needle to form an image.<br />

“In contrast to diagnostics, additional equipment is needed for the treatment inside the MRI gantry,<br />

as well as medical staff working close to the patient. But the space in the gantry is and remains<br />

limited," says Enrico Pannicke, drawing attention to the challenges posed by individual technical<br />

developments: finding solutions that eliminate the additional power cables, that meet the sterility<br />

demands of an operation, that improve access to the patient, that optimise patient positioning...<br />

The engineers focus on the modular design of a patient table that meets the different scenarios of<br />

an intervention. “It is important,” says Enrico Pannicke, "to ensure that the electronic components<br />

operate in a strong magnetic field and do not interfere with the sensitive measuring system of the<br />

MRI."

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