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ACR Congress Review 2019

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etween January 2008 and December 2015. Among 10,442 patients identified, 36.5% swapped to a<br />

non-TNFi drug, most commonly abatacept (54.2%). The remaining 63.5% switched to a cycling regimen<br />

(second TNFi), most commonly adalimumab (41.2%). For subsequent lines of therapy, non-TNFi drugs<br />

were more common. Patients who swapped were significantly older and sicker than those who cycled<br />

(P

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