Russia through the prism of the world biopharmaceutical market
Russia through the prism of the world biopharmaceutical market
Russia through the prism of the world biopharmaceutical market
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Biotechnology<br />
Journal<br />
6 © 2007 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim<br />
BTJ 07/07 | TD | DOI 10.1002/biot.200700091<br />
Table 2. Recombinant <strong>biopharmaceutical</strong>s and mAbs registered in RF [28] (drugs included in <strong>the</strong> DLO list are indicated as bold characters)<br />
Registered trademark in RF Manufacturer Indication Remarks<br />
Hunan insulin and analogues (ca. 40 trademarks registered in RF)<br />
Biotechnol. J. 2007, 2<br />
Actrapid NM, Mixtard 30 NM, Novo Nordisk Insulin-dependent Temporary license purchased<br />
Protafan NM<br />
Levemir (Insulin detemir)<br />
Novo Rapid (insulin aspart)<br />
(dominant supplier) diabetes mellitus in 1999 by A/S Bryntsalov A, RF<br />
Humulin M3, NPH, R<br />
Humalog (Insulin lispro)<br />
Lilly (dominant supplier)<br />
Insuman Rapid GT, Basal GT,<br />
Comb 25GT<br />
Lantus (Insulin glargin)<br />
Aventis (dominant supplier)<br />
Biosulin H, P Pharmstandard, RF<br />
+Marvell, India<br />
Gansulin P, H, 30P Dongbao, China<br />
Insuran R, NPH IBCH RAS, RF<br />
Rinsulin R A/S National Biotechnologies, Developed by A/S<br />
Rinsulin NPH RF since 2004 Biopreparat, RF<br />
License purchased by Sedico,<br />
Egypt www.sedico.ru<br />
Interferons<br />
Ropheron-A (rIFNα-2a)<br />
Pegasis (pegylated α-2b)<br />
Roche Hepatitis B and C, oncology<br />
Alpharona (rIFNα-2b) Pharmaclon, RF<br />
Intron A (rIFNα-2b) Shering Plough (Brinny),<br />
Pegintron (pegylated) Ireland<br />
Realderon (rIFNα-2b) Teva, Israel Distributed by SICOR, Lithuania<br />
Reaferon EC (rIFNα-2b) GNC Vector, First domestic rIFN (gene<br />
Reaferon EC-Lipint liposomal Vector-Medica, RF syn<strong>the</strong>sized by IBCH and <strong>the</strong><br />
Infagel ointment<br />
Recolin<br />
GNC Vector)<br />
Altevir liquid, (rIFNα-2b, Bioprocess subsidiary Registered since 2006<br />
free <strong>of</strong> HSA) Pharmapark, RF<br />
Viferon (rIFN-α), uvulae and Feron, RF Viral, bacterial, and Formulation by Gamaleya<br />
ointment, supplemented by www.viferon.com chlamydiosis in pregnancy Institute <strong>of</strong> Epidemiology and<br />
vitamins C and E) and newborn children, AIDS Microbiology<br />
Kipferon (rIFNα-2b in combination Alfarm, RF<br />
with human leukocyte IgM, IgA, IgG) www.alfarm.ru<br />
Giaferon (rIFNα-2b) A/S Vitafarma, RF<br />
Genferon (rIFNα-2b) Biocad, RF<br />
Grippferon ((rIFNα-2b, nasal form) Firn-M, RF Flu and related infections<br />
Ophthalm<strong>of</strong>eron<br />
(rIFNα-2b + dimedrol)<br />
Eye infections<br />
Gerpferon (rIFNα-2b + acyclovir +<br />
lidocain ointment)<br />
herpes<br />
Ber<strong>of</strong>or (rIFNα-2c) Boehringer Ingelheim, Oncology, hepatitis B, Registration in RF expired<br />
Germany ophthalmology<br />
Avonex (rIFNβ-1a) Biogen B.V., <strong>the</strong> Ne<strong>the</strong>rlands,<br />
Gedeon Richter<br />
Multiple sclerosis<br />
GALLEY PROOF
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