Use of tPA After Publication of ECASS III - American Stroke ...

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Background • The American Heart Association subsequently published a Science Advisory in May 2009 recommending treatment of eligible AIS patients up to 4.5 hours from onset of symptoms. • It remains uncertain what impact the publication of ECASS III has had on the utilization of tPA in clinical practice in the United States. – Did tPA use increase? – Did door-to-needle times increase? Stroke. 2009;40(8):2945-2948.
Background • The American Heart Association Get With The Guidelines Stroke (GWTG-Stroke) registry is a national quality improvement initiative and database that includes data from over 1,000,000 AIS patients treated at ~1,500 hospitals throughout the United States.
Page 1 and 2: Use of tPA After Publication of ECA
Page 3: Background • The NINDS rtPA Strok
Page 7 and 8: Methods • We queried the GWTG-Str
Page 9 and 10: Results
Page 11 and 12: Among Patients Treated 3 to 4.5 Hou
Page 17 and 18: Patients Treated Within 3 hours
Page 19 and 20: Among Patients Treated Within 3 Hou
Page 21 and 22: Limitations • Data were collected
Page 23 and 24: Conclusions • An increased percen
Page 25 and 26: Conclusions • Overall, treatment

Use of tPA After Publication of ECASS III - American Stroke ...

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