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The Operating Theatre Journal July 2022

The Operating Theatre Journal July 2022

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Success stories written by MEDICA – how a small developer team with

a prototype in their pocket became one of the biggest exhibitors

Again, many programme highlights feature start-ups

As one of the world’s leading medical trade fairs, MEDICA in Düsseldorf is

one of the most important platforms for start-up teams seeking to enter

the healthcare industry and who are looking for investors, opportunities for

cooperation and also first-time users of their product ideas. From November

14 to 17, 2022, for the duration of MEDICA, numerous programme highlights

will again offer young entrepreneurs the perfect opportunity to present

themselves to international experts from the healthcare sector: the 11th

MEDICA Start-up COMPETITION, 14th Healthcare Innovation World Cup, the

MEDICA START-UP PARK and a total of over 100 start-up exhibitions at the

MEDICA CONNECTED HEALTHCARE FORUM are just an example.

In addition, several hundred start-ups or scale-ups (which have entered the

next phase of development) will participate as exhibitors at MEDICA 2022,

either with joint stands or with a stand of their own. The current trend in

registrations for exhibitors points towards a participation rate that exceeds

that of the previous year (MEDICA 2021: 3033 participants) with a notable

expansion in the booked floor capacity.

Young companies like Rapid Response Revival are responsible for this

increase in booked floor capacity. In 2018, they participated for the first

time, at the central meeting point for start-ups, MEDICA START-UP PARK.

Since then, their business has grown exponentially. Thus, Rapid Response

Revival is travelling from Australia to MEDICA this year, too, and will occupy

one of the largest stands.

The team of developers has committed themselves and their product to

meet a global challenge; sudden cardiac arrest. Every year, six million

people worldwide die of this condition. This often happens at home, where

no life-saving defibrillator is present in time.

Therefore, Rapid Response Revival developed “CellAED”, an inexpensive

defibrillator for use by lay persons, and started marketing it. In 2019,

the first prototype was exhibited at MEDICA: “We met many people who

recognised our potential and wanted to be part of our endeavour in

different parts of the world”, Luke Starr, Chief Communications Officer at

Rapid Response Revival, remembers the promising start-up phase. Much has

happened since then. “We will be presenting a matured product at MEDICA

2022”, says Starr, looking forward to the trade fair which will take place in

mid-November.

As compact as a bar of chocolate, with huge potential

The new version of the defibrillator is no bigger than a bar of chocolate,

connects to a network and shows that it is ready for action. “CellAED”

helps first responders save lives until professional aid arrives. The device is

intended for integration into various emergency alert systems, and according

to Starr, could dramatically change first aid response globally. More than 70

countries have already issued a certification. The device has been approved

for the market in the EEA, the UK, Australia and New Zealand.

The device should remain affordable wherever it is sold: “The device costs

around 240 Euro. A subscription of approximately ten Euros each month

is also required for ongoing support, which for example includes access

to diagnostic data”, says Starr. CellAED is one-tenth the price, size and

weight of many of the other current systems on the market, which makes

the defibrillator perfect for home use. “This device will change society’s

reaction to sudden cardiac arrest in a fundamental way”, says Starr.

To this end, the upcoming participation in the trade fair is vital: “At MEDICA

2022 we will present both our development and the opportunities that it

proffers to a professional audience”, says Starr, adding: “We want to sell

millions of devices. We’re therefore cooperating with several manufacturers

and are aiming to produce 200,000 devices each month by the end of 2023”.

Starr thinks this is realistic: “We have the capacity to meet this challenge,

we meet the legal requirements and we have a team that can solve potential

problems”. One important reason for their success up to now is attributed

to the fact that, unlike larger competitors, this company concentrates on a

single application. This experience is probably very similar to that of other

start-ups which haven’t yet progressed as much as Rapid Response Revival

has, and which nevertheless have chosen MEDICA as a suitable platform – for

example, because of its competitions.

The 11th MEDICA Start-up COMPETITION has kicked off

The 11th MEDICA Start-up COMPETITION is seeking outstanding healthcare

solutions from start-ups in the health app, laboratory diagnostics and

artificial intelligence (AI) sectors in health care and robotics. The previous

year, the winning team was ‘Phonolyser’ from Finland, with their eponymous

product solution that offers intelligent analysis of cardiac sounds. The

cardiac sound analyser combines artificial intelligence (processing and

analysing signals), Doppler technology (ultrasound) and sound analysis to

comprehensively assess and examine for the presence of congenital heart

defects in children. The system aids in exact diagnosis. Bahman Doaeian,

co-founder and Chief Business Officer of Phonolyser, says: “Particularly in

the first weeks following our victory in Düsseldorf, we received a lot of

attention from the media and from investors in Europe”.

For Doaeian, MEDICA is one of the best platforms on which to introduce

medical technology in the world. “Here, we meet exactly the target group

we want to reach”, he says. Since last November, the “Phonolyser” has

been developed further; specifically, sensitivity has been improved (goal:

over 98 %) and the software has been optimised to make it easier for less

experienced doctors to operate the device. Clinical studies have seen a

lot of progress – for example, for testing a new algorithm. In this context,

Doaeian sees the extensive legal requirements for in the European Union

as a challenge that means that more support is needed for start-ups in

particular.

Applications for the 11th MEDICA Start-up COMPETITION can be submitted up

until September 21, 2022. The finals for the winning pitch will be held on the

November 15 on the event stage at the MEDICA CONNECTED HEALTHCARE

FORUM. Information on the competition and registration is available online

at: https://www.medica-tradefair.com/mac2.

The 14th Healthcare Innovation World Cup for “Internet of Medical

Things” solutions

Start-ups, scale-ups and small and medium businesses are also free to

submit their solutions for the “Internet of Medical Things (IoMT)” to the 14th

Healthcare Innovation World Cup. The best 12 selected finalists will be invited

to present their products – which can range from wearable technologies to

digital biomarkers, intelligent plasters and smart implants – at MEDICA 2022.

In 2021, the “eyemate” system by the Implandata Ophthalmic Products

company won the finals in Düsseldorf. This is an intelligent, implantable and

biocompatible micro sensor that provides telemedical care for glaucoma

patients. Glaucoma patients experience elevated intraocular pressure can

cause irreversible damage to the optic nerve and lead to blindness. Current

methods only allow this to be measured at an ophthalmologist’s office.

However, “eyemate” enables patients to continuously monitor themselves

at home. Ophthalmologists can use telemedicine to monitor the data

and, if necessary, intervene early on. The device gives patients a feeling

of security, as they will be informed in time and can act before elevated

intraocular pressure can damage their optical nerve. For Max Ostermeier,

CEO & Founder of Implandata Ophthalmic Products, this is a form of patient

empowerment, which also contributes to adherence to therapy: “This

will completely transform glaucoma therapy”. Ostermeier also states that

winning at the competition at MEDICA was a huge award and was important

for motivation. He says the media response led to being invited to more

presentations, which made it easier to win over investors.

Step by step towards international success

Nevertheless, the following still remains true for this start-up: “The

dominant factor is still the cost”, says Ostermeier. The implant is currently

being piggyback implanted in the eye during operations for glaucoma

or cataracts, where it remains indefinitely. “We meet the exacting CE

demands for permanent implants”, says Ostermeier. In the future, the

implant should be able to be implanted via minimally invasive injection,

without surgery, so that intraocular pressure can be monitored continually

during the early stages of the disease. Ostermeier went on to state that the

start-up works closely with ophthalmologists. In one or two years at the

earliest, the company will strive for further internationalisation – outside

German-speaking countries. The current focus: approval by the US Food and

Drug Administration (FDA).

The application phase for participation in this year’s Healthcare Innovation

World Cup ends on September 21, 2022. The pitches of the 12 finalists will

also take place on the event stage at the MEDICA CONNECTED HEALTHCARE

FORUM (on November 14).

The MEDICA START-UP PARK (Hall 12, E53), which has established itself as a

central venue for the creative founder scene, also prioritises networking. At

least 40 start-ups have already announced that they will participate, most

of them focusing on innovative digital healthcare solutions.

All information on MEDICA 2022 and the parts of the programme mentioned

above is available online at: https://www.medica-tradefair.com.

Author: Dr Lutz Retzlaff, freelance medical journalist (Neuss)

20 THE OPERATING THEATRE JOURNAL www.otjonline.com

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