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tenderness at the end of the second and fourth week were 0.69 * 0.3 and 0.46 0.3 1 respectively<br />

that were significantly less @ < 0.05) than 1.09 * 0.33, the mean baseline score for joint<br />

tenderness (Figure 2).<br />

Comparison of pre (NSAIDs supplemented with MI&) and post treatment (Sallaki after<br />

withdrawal of NSAIDs) values<br />

When therapy with NSAlD was withdrawn and only Sallaki administered for a period of two<br />

weeks from the fourth week of study period, no significant difference in the joint tenderness<br />

score at the sixth as compared to the fourth week was observed. However the mean score for<br />

joint tenderness at the end of the sixth week was 0.46 h 0.35 that was significantly less (p < 0.05)<br />

than 1.09 * 0.33, the mean baseline score for joint pain (Figure 2).<br />

Joint swelling<br />

Comparison of pre flSAIDs therapy) and psi treatment (NSAIDs supplemented with ,%llakr}<br />

values<br />

Supplementing the existing NSAID therapy with Sallaki resulted in a significant reduction in the<br />

swelling of the affected joints at the 2-w&k and 4-week endpoint. The mean score for joint<br />

swelling at the end of the second and fourth week were 0.54 * 0.28 and 0.33 * 0.29 respectively<br />

that were significantly less (p < 0.05) than 0.82 * 0.27, the mean baseline score for jbint swelling<br />

(Figure 3)<br />

Comparison of pre (IvSAIDs supplemented with SalU) and post treatment (Sallaki sfter<br />

withdrawal of NWDs) values<br />

When therapy with NSAID was withdrawn and only Sallaki administered for a period of two<br />

weeks fiom the fourth week of study period, no significant difference in the joint swelling score<br />

at the sixth as compared to the fourth week was observed. However the mean score for joint<br />

swelling at the end of the sixth week was 0.34 * 0.33 that was significantly less @ < 0.05) than<br />

0.82 * 0.27, the mean baseline score for joint swelling (Figure 3).<br />

Morning stiffn~s<br />

Comparison of pre (1VUIDs therapyl and post treatment (NLUIDs supplemented with SallakI)<br />

values<br />

Supplementing the existing NSAID therapy with Sallaki resulted in a yignificant reduction in<br />

mcrning' stiffness of the affected joints at the 2-week and 4-week endpoint. The mean score for<br />

morning stiffness at the end of the second and fourth week were 0.7 0.34 and 0.47 0.3<br />

respectively that were significantly less @ < 0.05) than 1.05 * 0.46, the mean baseline score for<br />

morning stiffness pigure 4).<br />

Comparison of pre (NSAIDs supplemented with Sallaki) and post treatment (Salk& after<br />

withdrawal of NWDs) values<br />

When therapy with NSAlD was withdrawn and only Sallaki administered for a period of ,two<br />

weeks &om the fourth week of study period, no significant diffwence in the morning stiffness<br />

score at the sixth as compared to the fourth week was observed. However the mean ocore.for<br />

morning stiffness at the end of the sixth week wab 0.45 * 0.37 that was significantly less @ <<br />

0.05) than 1.05 * 0.46, the mean baseline score for morning stiffness (Figure 4).<br />

SELECT RESEARCH PAPERS ON EVIDENCE BASED AYURVEDIC DRUGS 144<br />

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