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Texas Biomed Science Report 2011-2012 - Texas Biomedical ...

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Letter from the<br />

President<br />

Dear Friends and Colleagues,<br />

I am very pleased to share with you the <strong>2011</strong>-12 biennial<br />

Scientific <strong>Report</strong> for the <strong>Texas</strong> <strong>Biomed</strong>ical Research Institute,<br />

formerly known as the Southwest Foundation for <strong>Biomed</strong>ical<br />

Research. We changed our name effective February 1, <strong>2011</strong><br />

to better identify what we do and to avoid confusion with<br />

our sister institution, the Southwest Research Institute.<br />

We hope this summary of research activities will be helpful<br />

to other academic organizations, scientists and scientists-intraining,<br />

pharmaceutical and biotechnology companies who may<br />

wish to interact with our researchers or utilize our non-human<br />

primate colonies, community leaders, federal agency personnel,<br />

and public officials. This publication is not intended to replace<br />

our Annual <strong>Report</strong>, which is focused on a broader audience,<br />

but to supplement our communications with individuals,<br />

groups and organizations who should know about our research<br />

efforts and unique combination of scientific resources.<br />

<strong>Texas</strong> <strong>Biomed</strong> has been an extraordinary source of intellectual<br />

capital for seven decades. The basic and translational research<br />

efforts here have deepened our understanding of the genetics of<br />

complex disorders, virally-induced diseases, normal physiology<br />

and many of the aberrations that lead to disease. All of this<br />

work is facilitated by large colonies of non-human primates,<br />

an extraordinary computer “ranch” of 8,000 processors that<br />

analyze genetic data, the most secure of bio-containment<br />

research environments, and human population studies that<br />

every day lead to remarkable insights into the pathogenesis of a<br />

variety of life-altering and life-threatening human illnesses.<br />

All of these activities are undertaken in the organizational<br />

setting of an independent, not-for-profit research institution.<br />

This permits us to take prompt advantage of new scientific<br />

opportunities, infusions of government and philanthropic support,<br />

and the wonderfully collaborative environment of San Antonio.<br />

We take our role as a pioneer in biomedical research in<br />

this region very seriously, and I hope this <strong>Report</strong> reflects<br />

that. When Tom Slick courageously founded this institution<br />

in December, 1941, there was no medical school in San<br />

Antonio, no university hospital, no University of <strong>Texas</strong> at<br />

San Antonio. There was just one important asset, the vision<br />

of a man who believed profoundly that basic research could<br />

change the world and advance the interests of humankind.<br />

Each day, we try to emulate and reinforce that vision … that<br />

extraordinary spirit. We reach out not just to this city, this region,<br />

or even to the United States, but to the world-at-large. Disease<br />

outbreaks in the most remote regions of the globe can have<br />

<strong>2011</strong>–<strong>2012</strong> Scientific <strong>Report</strong><br />

“<strong>Texas</strong> <strong>Biomed</strong> has been an extraordinary source of<br />

intellectual capital for seven decades. The basic and<br />

translational research efforts here have deepened our<br />

understanding of the genetics of complex disorders,<br />

virally-induced diseases, normal physiology and<br />

many of the aberrations that lead to disease.”<br />

devastating impacts right here at home. Conversely, new discoveries<br />

here can transform the lives of people far from our borders.<br />

I invite you to read about our work and to share in our<br />

mission. Improving the health of our global community is<br />

not just what we stand for; it is what we do every day.<br />

Kenneth P. Trevett, JD<br />

San Antonio, <strong>2012</strong><br />

3

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