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10.6.5 Standard of Care vs.<br />

Corticosteroid for Retinal<br />

Vein Occlusion Study ...... 154<br />

10.6.6 Intravitreal Anti-VEGF<br />

Therapy .................. 155<br />

10.7 Surgical Treatments ....... 156<br />

10.7.1 BRVO ..................... 156<br />

10.7.2 CRVO .................... 156<br />

10.7.2.1 Laser-Induced Venous<br />

Chorioretinal Anastomosis . 156<br />

10.7.2.2 Recombinant Tissue<br />

Plasminogen Activator ..... 156<br />

10.7.2.3 Radial Optic Neurotomy ... 157<br />

10.7.2.4 Intravitreal Triamcinolone:<br />

As Adjunctive Therapy ..... 158<br />

10.8 Prevention—Systemic<br />

Factor Control ............. 158<br />

10.9 Conclusion ............... 158<br />

Chapter 11<br />

New Perspectives in Stargardt’s Disease<br />

Noemi Lois<br />

11.1 Introduction .............. 166<br />

11.2 Epidemiology and Clinical<br />

Findings .................. 166<br />

11.3 Imaging Studies .......... 169<br />

11.3.1 Fluorescein Angiography .. 169<br />

11.3.2 Indocyanine Green<br />

Angiography .............. 170<br />

11.3.3 Fundus Autofluorescence .. 170<br />

11.3.4 Optical Coherence<br />

Tomography .............. 172<br />

11.4 Electrophysiology<br />

and Psychophysics ........ 172<br />

11.5 Histopathology ........... 174<br />

11.6 Differential Diagnosis ...... 174<br />

11.7 Genetics and Molecular<br />

Biology ................... 174<br />

11.8 Animal Models of STGD-<br />

FFM ...................... 177<br />

11.9 Current and Future<br />

Treatments ............... 177<br />

Chapter 12<br />

Idiopathic Macular Telangiectasia<br />

Peter Charbel Issa, Hendrik P.N. Scholl,<br />

Hans-Martin Helb, Frank G. Holz<br />

12.1 Introduction .............. 183<br />

12.2 Type 1 Idiopathic Macular<br />

Telangiectasia ............. 183<br />

12.2.1 Epidemiology ............. 183<br />

12.2.2 Diagnostic Approach and<br />

Clinical Findings .......... 185<br />

12.2.3 Functional Implications ... 185<br />

12.2.4 Pathophysiological<br />

Considerations ............ 186<br />

12.2.5 Therapy .................. 186<br />

12.3 Type 2 Idiopathic Macular<br />

Telangiectasia ............. 187<br />

12.3.1 Epidemiology ............. 188<br />

12.3.2 Diagnostic Approach and<br />

Clinical Findings ........... 188<br />

12.3.3 Functional Implications .... 189<br />

12.3.4 Associated Diseases ....... 192<br />

12.3.5 Pathophysiological<br />

Considerations ............ 192<br />

12.3.6 Therapeutic Approaches ... 193<br />

12.4 Type 3: Idiopathic Macular<br />

Telangiectasia ............. 194<br />

12.5 Perspectives .............. 194<br />

Chapter 13<br />

Artificial Vision<br />

Peter Walter<br />

13.1 Introduction .............. 199<br />

13.2 Current Concepts<br />

for Restoring Vision Using<br />

Electrical Stimulation ...... 200<br />

13.3 Interfacing the Neurons .... 200<br />

13.3.1 Epiretinal Stimulation ...... 201<br />

13.3.2 Subretinal Approach ....... 203<br />

13.3.3 Transchoroidal, Transscleral,<br />

and Suprachoroidal<br />

Stimulation ............... 203<br />

13.3.4 Optic Nerve Approach ..... 204<br />

13.3.5 Cortical Prosthesis ......... 204<br />

13.4 Pixel Vision and Filters ..... 204<br />

13.5 Outlook .................. 206<br />

13.6 Conclusion ................ 206<br />

Subject Index .................. 211<br />

Contents XIII

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