Liquid Surgery Without Scars

Recommendations

Info

Biochemistry along with photographic tricks of “Soft Focus” are traditionally used in cosmetics as methods to soften the signs of wrinkle appearance. So far most anti-wrinkle products give weak results, and most biochemical compounds simply don’t satisfy the consumers, as they very often change to use a different product without committing to any of them long term. Consumers are looking for immediate signs of skin improvement, as well as permanent amelioration in skin structure with disappearance of age lines. To obtain good visible results, many women and men have decided to use more efficient methods than topical applications, leading to a dramatic increase of the number of face surgeries. However, they are not without risks, and need to be renewed frequently to maintain the young look. The trend today is to postpone surgeries as much as possible and use softer efficient methods to reduce wrinkles. Today FDA has approved BOTOX® Cosmetics as an aesthetic treatment to temporarily improve the appearance of glabellar lines by targeting the muscles that cause them with local injections. BOTOX® Cosmetics is not without risks either. BOTOX® (Botulinum toxin) is a toxin and can be potent in high concentration. Only small, diluted amounts of BOTOX® are used in treatments to reduce facial wrinkles. The most common side effects are headache and temporary redness or bruising of the skin. There is a chance that non-targeted muscles could be affected and weakened. This could cause drooping of the eyelid if BOTOX® seeps below the eyebrow and into the muscle that controls eyelid function. The effect is not permanent, but can be found most disturbing, as it only goes away as BOTOX® wears off, in about 5-6 months. We were inspired to create even an easier solutions than BOTOX® Cosmetics with high efficiency and user friendly usage. Fiflow® BTX is a raw material, which in cosmetic formulations acts in multiple levels imparting BOTOX®-like effects without surgeries, injections or unwanted side effects. Fiflow® BTX Fiflow® BTX Fiflow® BTX is based on a blend of medical grade perfluorocarbons (PFC), which are not drugs, as they only act as gas carriers. The performance of Fiflow® BTX is based on four mechanisms permitting strong and fast visible results, and more importantly, long term improvement of age lines. First mechanism: very fast penetration of the dermis and long half-life with different molecular weights. An old trick in cosmetic formulations is to use esters or oils, which penetrate quickly and instantaneously reduce the wrinkles. As they have small molecular weights, they increase the lipid content of the skin, increasing the volume of the dermis. This effect does not last long, as esters penetrate quickly to the deeper skin levels, retransforming the dermis volume back to normal. Fiflow® BTX is developed based on a combination of PFCs with variable molecular weighths and half-lives, to maximise the acting time in the dermis. Low molecular weight PFCs penetrate quickly allowing immediate visible results. High molecular weight PFCs penetrate slower maintaining the initial results and further treating the dermis. The halflive of a Fiflow® BTX is eleven days, which is the time how long the results can last after stopping the application. Second mechanism: instant skin volume increase based on volume structure of PFCs and their omniphobic properties. PFCs are not watersoluble nor oil soluble materials, hence called omniphobic. The inclusion of them in the intercellular cement, which is constituted from water, phospholipids and lipids as lamellar flat 2D liquid crystals, creates volume by 3D hexagonal micelle structure. This phenomena is comparable to ice versus water; ice is structured, volumised water. Based on skin surface studies, Fiflow® BTX increases the volume of dermis by 10 –15%, reducing the appearance of fine lines. Third mechanism: BOTOX®-type strong muscular relaxation. Deep wrinkles in the facial area are due to muscular effect, as the muscles get tense and shorten due to small electrical impulses. This can be reduced with insulating the muscles from electrical forces by dielectrics. Fiflow® BTX is a dielectric, and when used as a topical application, it will allow the glabellar muscles to relax and let them to find the natural position. This will immediately improve the skin appearance and reduce the wrinkles, which can be easily demonstrated by half-face tests. Number and depth of wrinkles decreases dramatically after 28-day Fiflow® BTX treatment.
Fourth mechanism: cell cleaning from Carbon Dioxide refreshing the cellular metabolism. Skin’s uptake of Oxygen starts to decline at age of 20 and is reduced by 50 % by age of 50. Oxygen is compulsory to the skin. Urban pollutions have lowered the overall level of oxygen in the environment to ca. 21%. This level is about half of what the air use to contain. Further, the skin is the last organ where inhaled oxygen travels, because oxygen depletion of the skin is not as detrimental as to other organs. Oxygen depletion and Carbon Dioxide accumulation lead to poor cell respiration which causes dehydration, uneven skin tone and dull skin. It is probably the largest contributor to the pre-mature aging of the skin, as Carbon Dioxide hinders or stops bio-pathways for cell metabolism. PFCs are the best gas carriers known to science. Fiflow® BTX can solubilise Oxygen and Carbon Dioxide, mimicking the function of hemoglobin. Fiflow® BTX carries Oxygen into the dermis, where it will diffuse from a region of higher partial O2 pressure to a region of lower partial O2 pressure. As Carbon Dioxide is more soluble in Fiflow® BTX than Oxygen, it will immediately replace Oxygen in Fiflow® BTX and will be carried out by it. This will allow cells to breathe normally and refresh their biological functions, leading to much better skin appearance. In medical world, pre-matured babies are saved thanks to PFCs, as in liquid breathing Oxygen is carried by PFCs to their brains and permanent damages are avoided. Efficacy Testing The Oxygen carrying capacity is directly comparable to the concentration of PFC used. The more PFCs are used in the cosmetic formula, the more Oxygen can be found in the skin. The Oxygen content of the skin can be measured transcutaneously by the means of polarizable probe by an Oxymonitor, results presented in the graph. Images of skin topography analyses before and after Fiflow® BTX treatment. Skin volumising effect 10-15% after 7 days treatment. A 14 day panel test was made with 30 women, aged 35-40 years with visible wrinkles around eyes. An emulsion with 10% Fiflow® BTX was applied twice a day for one week. After seven days the treatment was finished and the moisture of the skin was measured, as well as the skin profile was analysed. The moisture content was increased gradually during the period, reaching 52% increase. The moisture content remains at high level for eleven days, which is the half-life of Fiflow® BTX. The skin topography analyses were made to analyse the efficiency of Fiflow® BTX. The evolution of the skin surface during anti-aging treatment is determined by comparition relief parameters obtained by the shadow casting method. The number of wrinkles, depth of the wrinkles and the length of the wrinkles were analysed and as a results a 10-50% increase in volume was found after seven days topical treatment of 10% Fiflow® BTX. 3D structure of Fiflow® BTX Oxygen contents found in the dermis as a function of quantity of PFC
Page 1: Fiflow® BTX Liquid Surgery Without
Page 5 and 6: Fiflow® BTX Cream at 10%(N° 1904-

Liquid Surgery Without Scars

Create successful ePaper yourself

Delete template?

Save as template?