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References<br />
1. Hening W, Allen R, Earley C, Kushida C, Picchietti D, Silber M. The treatment of restless<br />
<strong>legs</strong> <strong>syndrome</strong> and periodic limb movement disorder: an American Academy of<br />
Sleep Medicine review. Sleep. 1999;22:970-999.<br />
2. Chesson AL Jr, Wise M, Davila D, et al. Practice parameters for the treatment of<br />
restless <strong>legs</strong> <strong>syndrome</strong> and periodic limb movement disorder: an American<br />
Academy of Sleep Medicine report. Sleep. 1999;22:961-968.<br />
3. National Heart, Lung, and Blood Institute. <strong>Restless</strong> Legs Syndrome: Detection and<br />
Management in Primary Care. Washington DC: National Institutes of Health; March<br />
2000. NIH Publication No. 00-3788.<br />
4. Allen RP, Picchietti D, Hening WA, et al. <strong>Restless</strong> <strong>legs</strong> <strong>syndrome</strong>: diagnostic criteria,<br />
special considerations, and epidemiology. A report from the <strong>Restless</strong> Legs<br />
Syndrome Diagnosis and Epidemiology Workshop at the National Institutes of<br />
Health. Sleep Med. 2003;4:101-119.<br />
5. Phillips B, Young T, Finn L, Asher K, Hening WA, Purvis C. Epidemiology of restless<br />
<strong>legs</strong> symptoms in adults. Arch Intern Med. 2000;160:2137-2141.<br />
6. Lavigne GJ, Montplaisir JY. <strong>Restless</strong> <strong>legs</strong> <strong>syndrome</strong> and sleep bruxism: prevalence<br />
and association among Canadians. Sleep. 1994;17:739-743.<br />
7. Ulfberg J, Nystrom B, Carter N, Edling C. Prevalence of restless <strong>legs</strong> <strong>syndrome</strong> among<br />
men aged 18 to 64 years: an association with somatic disease and neuropsychiatric<br />
symptoms. Mov Disord. 2001;16:1159-1163.<br />
8. Ulfberg J, Nystrom B, Carter N, Edling C. <strong>Restless</strong> <strong>legs</strong> <strong>syndrome</strong> among workingaged<br />
women. Eur Neurol. 2001;46:17-19.<br />
9. Rothdach AJ, Trenkwalder C, Haberstock J, Keil U, Berger K. Prevalence and risk<br />
factors of RLS in an elderly population: the MEMO Study. Memory and morbidity in<br />
Augsburg elderly. Neurology. 2000;54:1064-1068.<br />
10. Allen RP, Earley CJ. Defining the phenotype of the restless <strong>legs</strong> <strong>syndrome</strong> (RLS)<br />
using age-of-symptom-onset. Sleep Med. 2000;1:11-19.<br />
11. Allen RP, La Buda MC, Becker P, Earley CJ. Family history study of the restless <strong>legs</strong><br />
<strong>syndrome</strong>. Sleep Med. 2002;3(suppl):S3-S7.<br />
12. Winkelmann J, Muller-Myhsok B, Wittchen HU, et al. Complex segregation analysis<br />
of restless <strong>legs</strong> <strong>syndrome</strong> provides evidence for an autosomal dominant mode of<br />
inheritance in early age at onset families. Ann Neurol. 2002;52:297-302.<br />
13. Bonati MT, Ferini-Strambi L, Aridon P, Oldani A, Zucconi M, Casari G. Autosomal dominant<br />
restless <strong>legs</strong> <strong>syndrome</strong> maps on chromosome 14q. Brain. 2003;126(pt 6):1485-1492.<br />
14. Desautels A, Turecki G, Montplaisir J, Sequeria A, Verner A, Rouleau GA.<br />
Identification of a major susceptibility locus for restless <strong>legs</strong> <strong>syndrome</strong> on chromosome<br />
12q. Am J Hum Genet. 2001;69:1266-1270.<br />
15. Berger K. Non-opioid analgesics and the risk of restless leg <strong>syndrome</strong>—a spurious<br />
association? Sleep Med. 2003;4:351-352.<br />
16. Earley CJ, Allen RP, Beard JL, Connor JR. Insight into the pathophysiology of restless<br />
<strong>legs</strong> <strong>syndrome</strong>. J Neurosci Res. 2000;62:623-628.<br />
17. Earley CJ, Conner JR, Beard JL, Malecki EA, Epstein DK, Allen RP. Abnormalities in<br />
CSF concentrations of ferritin and transferrin in restless <strong>legs</strong> <strong>syndrome</strong>. Neurology.<br />
2000;54:1698-1700.<br />
18. Lee KA, Zaffke ME, Baratte-Beebe K. <strong>Restless</strong> <strong>legs</strong> <strong>syndrome</strong> and sleep disturbance<br />
during pregnancy: the role of folate and iron. J Womens Health Gend Based Med.<br />
2001;10:335-341.<br />
19. Winkelman JW, Chertow GM, Lazarus JM. <strong>Restless</strong> <strong>legs</strong> <strong>syndrome</strong> in end-stage<br />
renal disease. Am J Kidney Dis. 1996;28:372-378.<br />
20. Ondo W, Jankovic J. <strong>Restless</strong> <strong>legs</strong> <strong>syndrome</strong>: clinicoetiologic correlates. Neurology.<br />
1996;47:1435-1441.<br />
21. Winkelmann J, Stautner A, Samtleben W, Trenkwalder C. Long-term course of restless<br />
<strong>legs</strong> <strong>syndrome</strong> in dialysis patients after kidney transplantation. Mov Disord.<br />
2002;17:1072-1076.<br />
22. Michaud M, Chabli A, Lavigne G, Montplaisir J. Arm restlessness in patients with<br />
restless <strong>legs</strong> <strong>syndrome</strong>. Mov Disord. 2000;15:289-293.<br />
23. Montplaisir J, Lapierre O, Lavigne G. The restless leg <strong>syndrome</strong>: a condition associated<br />
with periodic or aperiodic slowing of the EEG [in French]. Neurophysiol Clin.<br />
1994;24:131-140.<br />
24. Trenkwalder C, Hening WA, Walters AS, Campbell SS, Rahman K, Chokroverty S.<br />
Circadian rhythm of periodic limb movements and sensory symptoms of restless<br />
<strong>legs</strong> <strong>syndrome</strong>. Mov Disord. 1999;14:102-110.<br />
25. Hening WA, Walters AS, Wagner M, et al. Circadian rhythm of motor restlessness<br />
and sensory symptoms in the idiopathic restless <strong>legs</strong> <strong>syndrome</strong>. Sleep. 1999;22:901-<br />
912.<br />
26. Walters AS, LeBrocq C, Dhar A, et al. Validation of the International <strong>Restless</strong> Legs<br />
Syndrome Study Group rating scale for restless <strong>legs</strong> <strong>syndrome</strong>. Sleep Med.<br />
2003;4:121-132.<br />
27. Trenkwalder C, Garcia-Borreguero D, Montagna P, et al. Ropinirole in the treatment<br />
of restless <strong>legs</strong> <strong>syndrome</strong>: results from the TREAT RLS 1 study, a 12-week, randomised,<br />
placebo controlled study in 10 European countries. J Neurol Neurosurg<br />
Psychiatry. 2004;75:92-97.<br />
28. Earley CJ. Clinical practice: restless <strong>legs</strong> <strong>syndrome</strong>. N Engl J Med. 2003;348:2103-<br />
2109.<br />
29. Wetter TC, Stiasny K, Winkelmann J, et al. A randomized controlled study of pergolide<br />
in patients with restless <strong>legs</strong> <strong>syndrome</strong>. Neurology. 1999;52:944-950.<br />
30. Montplaisir J, Nicolas A, Denesle R, Gomez-Mancilla B. <strong>Restless</strong> <strong>legs</strong> <strong>syndrome</strong><br />
improved by pramipexole: a double-blind randomized trial. Neurology. 1999;52:938-<br />
943.<br />
31. Allen RP, Earley CJ. Augmentation of the restless <strong>legs</strong> <strong>syndrome</strong> with carbidopa/levodopa.<br />
Sleep. 1996;19:205-213.<br />
32. Ferini-Strambi L, Oldani A, Castronovo V, Zucconi M. RLS augmentation and<br />
pramipexole long-term treatment. Neurology. 2001;56(suppl 3):A20-A21.<br />
33. Becker PM, Ondo W, Sharon D. Encouraging initial response of restless <strong>legs</strong> <strong>syndrome</strong><br />
to pramipexole. Neurology. 1998;51:1221-1223.<br />
34. Silber MH, Shepard JW Jr, Wisbey JA. Pergolide in the management of restless <strong>legs</strong><br />
<strong>syndrome</strong>: an extended study. Sleep. 1997;20:878-882.<br />
35. Telstad W, Sorensen O, Larsen S, Lillevold PE, Stensrud P, Nyberg-Hansen R.<br />
Treatment of the restless <strong>legs</strong> <strong>syndrome</strong> with carbamazepine: a double blind study.<br />
Br Med J (Clin Res Ed). 1984;288:444-446.<br />
36. Garcia-Borreguero D, Larrosa O, de la Llave Y, Verger K, Masramon X, Hernandez G.<br />
Treatment of restless <strong>legs</strong> <strong>syndrome</strong> with gabapentin: a double-blind, cross-over<br />
study. Neurology. 2002;59:1573-1579.<br />
37. National Heart, Lung, and Blood Institute Working Group on <strong>Restless</strong> Legs<br />
Syndrome. <strong>Restless</strong> <strong>legs</strong> <strong>syndrome</strong>; detection and management in primary care. Am<br />
Fam Physician. 2002;62:108-114.<br />
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