The Tandem Grignard- Oppenauer Oxidation

More documents

Recommendations

Info

Si Proposed Tandem Grignard- Grignard Br 1. Mg 2. PhCHO Oppenauer Oxidation Si O 3. PhCHO Mg Br 4. H + , H 2 O The 1st equivalent of benzaldhyde is for the Grignard Addition The 2nd equivalent of benzaldehyde is for the Oppenauer Oxidation Si O + OH
Si Br 1. Mg 2. PhCHO 3. H+, H 2 O Results �� 80% yield of TMS-PVK TMS PVK �� 100% yield of benzyl alcohol �� No alcohol precursor observed in 1H H NMR spectra �� Results demonstrate successful Grignard addition and complete oxidation Si O + OH
Page 1 and 2: The Tandem Grignard- Grignard Oppen
Page 3 and 4: What is Green Chemistry? “The The
Page 5 and 6: Applying Green Chemistry to Undergr
Page 7 and 8: How “Green Green” is the Baylis
Page 9 and 10: Silicon-Mediated Silicon Mediated B
Page 11 and 12: Synthesis of TMS-PVK TMS PVK ��
Page 13 and 14: Getting Started �� Our original
Page 15: How Did This Happen? �� A searc
Page 19 and 20: Improvements on the Reaction ��
Page 21 and 22: Reagents Utilized �� Grignard-O
Page 23 and 24: Reagents Utilized �� Also tried
Page 25 and 26: Paraformaldehyde �� Preliminary
Page 27: Questions?

The Tandem Grignard- Oppenauer Oxidation

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?