Experience with Lipid-based Nutrient ... - The iLiNS Project

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a. Studies that targeted stunted children Study Nature of intervention Report by investigator Maleta et al., 2004 - Malawi Kuusipalo et al., 2006), Malawi. S Adu-Afarwuah, PhD October 2010 • Chn 42-60 mo old • Mean LAZ: -3.2 (0.9) vs -3.0 (0.8) • RUTF Vs. Maize-Soy mix (500 kcal/d) • Folllow-up: 4 wk before supplementation, 12 during and 12 after). • Duration: 28 wk • Chn 6-17 mo old • Mean LAZ: -2.4 (0.9) vs -2.3 (1.0). • Fortified spread (22, 130, 264, 396 kcal/d milk-based or 126, 255, 386 kcal/d soy-based) Vs. No supplementation. • Duration: 12 wk. • No effect on linear growth • Mean length gain higher for FS ≥ 130 kcal/d. • Hb ↑ by 10-17g/L. • Milk-based FS 264 kcal/d had greatest effects 6
a. Studies that targeted stunted children, cont’d Study Nature of intervention Report by investigator Lopriore et al., 2004, Algeria Isanaka et al., 2009, Niger S Adu-Afarwuah, PhD October 2010 • Saharawi refugee children 36-72 mo • Mean LAZ range: -2.73 (0.55) to -3.97 (0.70). • Fortified spread (with/ w’out metronidazole) (~320 kcal/d), Vs Unfortified spread (with/w’out metronidazole), Vs. No supplementation. • Duration: 6 mo • Chn 6-60 mo old in 6 Intervention Vs. 6 Non-intervention Villages • Mean LAZ: -1.9 (1.3) Vs -2.2 (1.0) • RUTF (500 kcal/d) for 3 mo Vs No supplementation. 5 more mo of follow-up with no further supplementation. • Duration: 8 mo • Linear growth 30% faster in FS group at 3 mo than other two groups • At 6 mo, Hb ↑ in FS was ~ 2x those of 2 groups. • 36% ↓ in incidence of wasting - 58% ↓ in incidence of severe wasting 7
Page 1 and 2: Experience with Lipid-based Nutrien
Page 3 and 4: Scope of review • LNS was provide
Page 5: Number of studies included Number o
Page 9 and 10: . Studies that targeted non-stunted
Page 11 and 12: Effect of LNS on linear growth: Stu
Page 13 and 14: Effect of LNS on linear growth: Non
Page 15 and 16: Effect of LNS on severe wasting: St
Page 17 and 18: Effect of LNS on Hb conc. and anemi
Page 19 and 20: Effect size for change in Hb Effect
Page 21 and 22: Summary : Effect on severe wasting
Page 23 and 24: 5.0 4.0 3.0 2.0 1.0 S Adu-Afarwuah,
Page 25 and 26: Overall conclusions � Preventive

Experience with Lipid-based Nutrient ... - The iLiNS Project

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