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Tema 8 - Medic.ula.ve

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Inmunopatogenia del asma:<br />

Respuesta inflamatoria<br />

2 a 4 horas y máxima a las 24 horas:<br />

Acúmulo de Neutrófilos, eosinófilos, basófilos y cél<strong>ula</strong>s T<br />

CD4+ (fundamentalmente Th2)<br />

TNF liberado por los mastocitos incrementa la expresión de<br />

moléc<strong>ula</strong>s de adhesión en cél<strong>ula</strong>s endoteliales:<br />

E-selectin e ICAM

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