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Tema 4 - Medic.ula.ve

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Abbas A Immunol Cell Mol 1999; Janeway Immuno Biol 1999<br />

Inmunoglobulinas:<br />

ESTRUCTURA<br />

2 Cadenas<br />

pesadas (55 o<br />

70 kD)<br />

2 livianas (24 kD)<br />

Dominio: 110 aa<br />

5 clases o isotipos<br />

IgM (µ), IgG (γ),<br />

IgA (α), IgE (ε)<br />

e IgD (δ)<br />

Domino C<br />

Domino V<br />

Dominios<br />

Fab: sitio<br />

de unión al<br />

Ag<br />

Bisagra<br />

Fc: función<br />

efectora

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