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Pancreatitis

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Álvarez-Lerma et al; Recomendaciones para la monitorización de antibióticos en pacientes críticos ingresados en<br />

UCI; Enferm Infecc Micro Clin 2008:26 (4);230-9Federico P; Antimicrobial therapy in critically ill patients; Clin<br />

Pharmacokinet 2005 (44):1009-1034<br />

¿Cuál es el indice PK/PD para amikacina?<br />

- AUC/MIC<br />

- Cmax/MIC Concentración dependiente<br />

-Cmax/Cmin<br />

C<br />

Cmax/MIC> 10-12<br />

t<br />

AMPLIACIÓN DEL INTERVALO<br />

-Efecto postantibiótico<br />

- Menor toxicidad

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