Tema 15 - Medic.ula.ve
Tema 15 - Medic.ula.ve
Tema 15 - Medic.ula.ve
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INDUCCION DE CANCER:Cromosoma 5q 12p 18q 17pAlteracionPerdida Activación Perdida PerdidaGen APC K-ras DCC p53Hipometilacióndel DNANORMAL HIPERPROLIFERAADENO-I ADENO-T CARCINMETASTASISVogelstein B et al. N Eng J Med. 1988;319:525-532.Fearon ER et al. Cell. 1990;61:759-767.OTRAS ALTERACONES