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Best Practice Recommendations for the Prevention and ...

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<strong>the</strong> underlying surgical <strong>and</strong> non-surgical factors that<br />

have led to <strong>the</strong> infection. Fur<strong>the</strong>r surgical intervention<br />

is frequently required, depending upon <strong>the</strong> surgical<br />

problem, usually to remove devitalized tissue or infected<br />

<strong>for</strong>eign material, close a fistula or ulcer space or<br />

drain/remove a sinus tract. Multiresistant microorganisms<br />

such as MRSA, o<strong>the</strong>r Gram-negative bacteria or<br />

even fungi may be involved. Long-term antibiotics are<br />

usually required, based on <strong>the</strong> antimicrobial susceptibility<br />

patterns of <strong>the</strong> isolated microflora. Rehabilitation<br />

is frequently needed as part of <strong>the</strong> recuperation phase.<br />

Recommendation 8: Provide optimal local wound<br />

moisture balance to promote healing by choosing an<br />

appropriate dressing <strong>for</strong> <strong>the</strong> acute <strong>and</strong> chronic phases of<br />

surgical wound healing (NICE level 1+; RNAO level IV).<br />

Moist wound healing is one of <strong>the</strong> cornerstones<br />

of evidence-based wound care in both <strong>the</strong> acute<br />

<strong>and</strong> chronic settings. 44–50<br />

The advantages of moist<br />

wound healing include less intense <strong>and</strong> less prolonged<br />

inflammation; rapid keratinocytosis <strong>and</strong> increased<br />

fibroblast proliferation; an increased rate of collagen<br />

syn<strong>the</strong>sis <strong>and</strong> epi<strong>the</strong>lial cell migration, resulting in<br />

earlier angiogenesis; <strong>and</strong> faster contraction of fullthickness<br />

wounds. 45,46,49<br />

Acute surgical wounds<br />

Acute wounds (including surgical wounds) are caused<br />

by external trauma to <strong>the</strong> human body <strong>and</strong> follow<br />

a systematic process of repair, progressing through<br />

vascular, inflammatory, proliferation <strong>and</strong> maturation<br />

stages of healing. 48,51<br />

Wounds with minimal tissue loss that are closed<br />

surgically heal by primary intention when <strong>the</strong> closure<br />

joins <strong>the</strong> wound edges, eliminating dead space <strong>and</strong><br />

continued on page 26<br />

Volume 8, Number 1, 2010 Wound Care Canada<br />

25

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