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Le Nefopam - JLAR

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Association Néfopam - Morphine et<br />

Nausées - Vomissements<br />

Mc<br />

Lintock et<br />

al., 1988<br />

Du<br />

Manoir et<br />

al., 2003<br />

Tramoni<br />

et al.,<br />

2003<br />

Mimoz et<br />

al., 2001<br />

Mode<br />

d’administration<br />

et Dose Totale<br />

IM<br />

100 mg<br />

IV., Discontinue<br />

120 mg<br />

IV., Continue<br />

80mg/j<br />

IV., Discontinue<br />

120 mg<br />

Début de<br />

TT Nausées Vomissements<br />

Préop 30% vs 35% 9% vs 15%<br />

Perop 44% vs 44% 21% vs 20%<br />

Postop 19 % vs 38% -<br />

Perop 17% vs 39%<br />

IV 30 min<br />

IV 60 min<br />

Néfopam<br />

Placebo

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