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immunoglobuline

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STRUTTURA<br />

DUE IDENTICHE CATENE LEGGERE (L,Light) 23KDa<br />

DUE IDENTICHE CATENE PESANTI (H,Heavy) 50-70KDa<br />

DOMINI GLOBULARI (superfamiglia Ig)<br />

Cat.L V L C L<br />

Cat.H V H C H1 C H2 C H3 (o C H4)<br />

PONTI DISOLFURO<br />

(Intercatena/Intracatena)<br />

REGIONE CARDINE<br />

(flessibilità dell’Ig)<br />

OLIGOSACCARIDI<br />

(Soprattutto in C H2)<br />

V L<br />

V H<br />

C L<br />

Disulfide bond interchain(L-H)<br />

Disulfide bond intrachain<br />

C H1<br />

Disulfide bond interchain(H-H)<br />

C H2<br />

Hinge region<br />

C H3<br />

Charbohydrate<br />

Fig.Immunology and microbiology on-line(Modif)

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