Diagnostica di laboratorio
Diagnostica di laboratorio
Diagnostica di laboratorio
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Diagnosi <strong>di</strong> infezione latenteAntigeniESAT 6Early Secretion Antigen Target 6CFP 10Colture Filtrate Protein 10All stimulated T-lymphocytes secreteinterferon-, but the ESAT-6- and CFP-10-specific assays can only detectinterferon secreted fromT-lymphocytes produced as a result ofexposure to ESAT-6 and CFP-10antigen.In vivo and in vitro experiments haveshown that the combination ofESAT-6 and CFP-10 has a highersensitivity and specificity than PPD in<strong>di</strong>agnosis of TBA systematic review of rapid <strong>di</strong>agnostic tests for thedetection of tuberculosis infectionJ Dinnes, J Deeks, H Kunst, A Gibson, E Cummins, N Waugh, FDrobniewskiand A Lalvani•Health Technology Assessment; NHS R&D HTAProgramme; www.hta.ac.uk
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