ﭘﯿﮏ ﻫﺎی ﺩﻧﺒﺎﻟﻪ ﺩﺍﺭ - Behan chemical co.
ﭘﯿﮏ ﻫﺎی ﺩﻧﺒﺎﻟﻪ ﺩﺍﺭ - Behan chemical co.
ﭘﯿﮏ ﻫﺎی ﺩﻧﺒﺎﻟﻪ ﺩﺍﺭ - Behan chemical co.
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
. ﺩﺭﺍﺩ ﺩﻮﺟ و ﻩﺪﻨﯾﺁ<br />
C30 ﻞﯿﮑﻟﺁ یﺎﻫﺯﺎﻓ<br />
(Monomeric) یﺍ ﻩﺭﺎﭙﮑﺗ یﺎﻫ ﻩﺮﯿﺠﻧﺯ ﻦﯾﺮﺗ ﺪﻨﻠﺑ C30 یﺎﻫﺯﺎﻓ<br />
یﺯﺎﺳﺍﺪﺟ ﺖﻬﺟ ﺎﻫﺯﺎﻓ ﻦﯾﺍ . ﺪﻧﺍ ﻪﺘﻓﺮﮔ ﺭﺍﺮﻗ ﺱﺮﺘﺳﺩ ﺭﺩ " ﺍﺮﯿﺧﺍ ﻪﮐ ﺪﻨﺷﺎﺒﯿﻣ<br />
ﺩﺭﻮﻣ ﻥوﺭﺍو ﺯﺎﻓ HPLCﺭﺩ<br />
Carotenoid ﺲﻧﺍﺮﺗ<br />
و ﺲﯿﺳ یﺎﻫﺮﻣوﺰﯾﺍ<br />
ﻩﺪﺷ ﻩﺩﺭوﺁ 4 ﻞﮑﺷ ﺭﺩ ﻥﺁ ﻡﺍﺮﮔﻮﺗﺎﻣوﺮﮐ ﻪﮐ ﺖﺳﺍ ﻪﺘﻓﺮﮔ ﺭﺍﺮﻗ ﻩﺩﺎﻔﺘﺳﺍ<br />
ﺖﺒﺴﻧ C30 ﺯﺎﻓ ﯽﯾﺎﻨﺜﺘﺳﺍ ﺭﺎﺘﺧﺎﺳ ﻪﺑ ﺩﺮﻔﺑ ﺮﺼﺤﻨﻣ یﺯﺎﺳﺍﺪﺟ ﻦﯾﺍ . ﺖﺳﺍ<br />
ﻩﺪﻨﻫﺩ ﻥﺎﺸﻧ Solid State NMR ﻂﺳﻮﺗ C30 ﺯﺎﻓ ﻪﻌﻟﺎﻄﻣ . ﺩﻮﺸﯿﻣ ﻩﺩﺍﺩ<br />
ﺭﺎﯿﺴﺑ ﻥﺩﻮﺑ ﺐﺗﺮﻣ ﻪﺑ ﺎﻫﺯﺎﻓ<br />
ﻦﯾﺍ ﺩﺮﻔﺑ ﺮﺼﺤﻨﻣ یﺮﯾﺬﭘ ﺶﻨﯾﺰﮔ ﻪﮐ ﺖﺳﺍ ﻥﺁ<br />
یﺎﻫﺯﺎﻓ ﻂﺳﻮﺗ یﺯﺎﺳﺍﺪﺟ ﺖﻬﺟ ﺰﯿﻧ C30 ﺯﺎﻓ . ﺩﺭﺍﺩ ﻁﺎﺒﺗﺭﺍ ﺎﻬﻧﺁ یﻻﺎﺑ<br />
. ﺩﻮﺷ ﯽﻣ ﻩﺩﺎﻔﺘﺳﺍ ﯽﺑﺁ " ﺍﺪﯾﺪﺷ کﺮﺤﺘﻣ<br />
ﯽﻄﯾﺍﺮﺷ ﺮﻫ ﺭﺩ<br />
(Collapse)<br />
ﺵﺰﯾﺭوﺮﻓ ﺮﺑﺍﺮﺑ ﺭﺩ ﺩﻮﺧ ﺯﺍ ﺎﻫﺯﺎﻓ ﻦﯾﺍ<br />
ﻪﻄﻘﻧ ﻪﺑ ﺰﯿﻧ ﺍﺭ ﺩﺮﻔﺑ ﺮﺼﺤﻨﻣ ﺭﺎﺘﻓﺭ ﻦﯾﺍ ﻥﺍﻮﺗ ﯽﻣ ﻪﮐ ﺪﻨﻫﺩ ﯽﻣ ﻥﺎﺸﻧ ﺖﻣوﺎﻘﻣ<br />
C30 ﻞﯿﮑﻟﺁ ﺏوﺫ ﻪﻄﻘﻧ . ﺩﺍﺩ ﺖﺒﺴﻧ C30 یﺎﻫ ﻩﺮﯿﺠﻧﺯ یﻻﺎﺑ ﺏوﺫ<br />
ﺯﺍ ﻩﺩﺎﻔﺘﺳﺍ ﺩﺭﻮﻣ یﺩﺎﻋ ﯽﯾﺎﻣﺩ ﻂﯾﺍﺮﺷ ﺯﺍ ﺮﺗﻻﺎﺑ<br />
ﻪﮐ ﺖﺳﺍ 68-69°C یﺎﻣﺩ<br />
ﺭﺩﺎﻗ C30 ﺪﻣﺎﺟ ﻩﺮﯿﺠﻧﺯ ﺎﻣﺩ ﻦﯾﺍ ﺭﺩ . ﺪﺷﺎﺑ ﯽﻣ (30-40°C) ﺎﻬﻧﻮﺘﺳ ﻦﯾﺍ<br />
12<br />
ﯽﻠﯿﮑﻟﺁ یﺎﻫ ﻩﺮﯿﺠﻧﺯ و<br />
ﻦﯾﺍ ﻂﺳﻮﺗ PFP<br />
(PFP) ﻞﯿﻨﻓ وﺭﻮﻠﻓﺎﺘﻨﭘ یوﺎﺣ<br />
" ﻻﻮﻤﻌﻣ . ﺪﻨﺘﺴﻫ<br />
" ﻻﻮﻤﻌﻣ ﺎﻫﺯﺎﻓ ﻦﯾﺍ<br />
(Spacer) ﻂﺳﺍو ﺪﺣ ﻥﺍﻮﻨﻌﺑ ﺭﻮﻠﻓ ﺮﯿﻏ<br />
ﻪﺑ ،ﺪﻨﺘﺴﻫ ﯽﻠﯿﭘوﺮﭘ یﺎﻬﻫوﺮﮔ ﺩﺭﺍﻮﻣ ﺯﺍ یﺭﺎﯿﺴﺑ ﺭﺩ ﻪﮐ ﯽﻠﯿﮑﻟﺁ یﺎﻫ ﻩﺮﯿﺠﻧﺯ<br />
. ﺪﻧﻮﺷ ﯽﻣ ﺭﺎﺘﺧﺎﺳ ﻦﯾﺍ یﺭﺍﺪﯾﺎﭘ ﺚﻋﺎﺑ و ﻩﺪﺷ ﻩﺩﺍﺩ ﺪﻧﻮﯿﭘ ﺎﮑﯿﻠﯿﺳ ﺢﻄﺳ<br />
ﻞﻣﺎﺷ ﻩﺪﭽﯿﭘ یﺎﻫ ﻁﻮﻠﺨﻣ یﺯﺎﺳﺍﺪﺟ ﺖﻬﺟ ﻞﯿﻨﻓوﺭﻮﻠﻓﺎﺘﻨﭘ یﺎﻬﻧﻮﺘﺳ<br />
ﺎﺑ ﻩﺪﺷ ﻑﻼﺨﺘﺳﺍ ﮏﯿﺗﺎﻣوﺭﺁ<br />
ﺕﺎﺒﯿﮐﺮﺗ ،(To<strong>co</strong>pherols)<br />
ﻝوﺮﻓﻮﮐﻮﺗ<br />
ﺹﺍﻮﺧ ﻪﻌﻟﺎﻄﻣ ﺎﺑ<br />
. ﺪﻧﻮﺸﯿﻣ ﻩﺩﺎﻔﺘﺳﺍ ﺎﻫ<br />
Taxane<br />
و ﻞﯿﮑﻟﺁ یﺎﻬﻣوﺮﮔ<br />
یﺯﺎﺳﺍﺪﺟ ﺖﻬﺟ ﺎﻫﺯﺎﻓ ﻦﯾﺍ ﻪﮐ ﺪﻧﺍ ﻩﺪﯿﺳﺭ ﻪﺠﯿﺘﻧ ﻦﯾﺍ ﻪﺑ PFP یﺭﺍﺩﺯﺎﺑ<br />
ﺎﻣﺍ . ﺪﻨﺷﺎﺒﻣ ﺐﺳﺎﻨﻣ ،ﺪﻨﺘﺴﻫ ﮏﯿﺗﺎﻣوﺭﺁ یﺎﻬﻫوﺮﮔ یﺍﺭﺍﺩ ﻪﮐ ﯽﯾﺎﻬﻟﻮﮑﻟﻮﻣ<br />
ﻝﺎﺣ ﺮﻬﺑ<br />
ﯽﻟو ،ﺖﺳﺍ ﻩﺪﺸﻧ ﻪﺋﺍﺭﺍ ﺭﺎﺘﻓﺭ ﻦﯾﺍ ﺖﻬﺟ ﯽﻤﺴﯿﻧﺎﮑﻣ ﺯﻮﻨﻫ ﻪﻧﺎﻔﺳﺎﺘﻣ<br />
ﺕﺎﺒﯿﮐﺮﺗ یﺭﺍﺩﺯﺎﺑ ﺭﺩ ﻢﻬﻣ ﯽﺸﻘﻧ ﻥﺍﻮﻨﻋ ﻪﺑ ﻪﮐ ﺍﺭ π-π<br />
ﺶﻨﮐ ﻢﻫ ﺮﺑ ﺮﺛﺍ<br />
. ﺪﻧﺭﺎﻤﺷ ﯽﻣ ﻞﻤﺘﺤﻣ ﺰﯿﻧ ،ﺩﻮﺑ ﻩﺪﺷ ﺵﺭﺍﺰﮔ ﺝوﺩﺰﻣ ﮏﯿﺗﺎﻣوﺭﺁ<br />
وﺩ و ﯽﻓﻼﺨﺘﺳﺍ ﮏﺗ ﺕﺎﺒﯿﮐﺮﺗ یﺭﺍﺩﺯﺎﺑ ﻪﻨﯿﻣﺯ ﺭﺩ ﺰﯿﻧ ﯽﺗﺎﻌﻟﺎﻄﻣ ﻦﯿﻨﭽﻤﻫ<br />
ﻦﯾﺍ ﺯﺍ ﯽﺸﺨﺑ ﺭﺩ . ﺖﺳﺍ ﻩﺪﺷ ﻡﺎﺠﻧﺍ PFP ﺯﺎﻓ یوﺭ ﺮﺑ ﻦﯿﻟﺎﺘﻔﻧوﺮﺘﯿﻧ ﯽﻓﻼﺨﺘﺳﺍ<br />
ﺰﯿﻟﺎﻧﺁ یﺍﺮﺑ ﺪﻨﺘﺷﺍﺩ ﯽﻧﺎﺴﮑﯾ ﯽﯾﺎﮑﯿﻠﯿﺳ ﺮﺘﺴﺑ ﻪﮐ ﯽﻠﯿﻨﻓ و C18 ﺯﺎﻓ<br />
ﻪﻌﻟﺎﻄﻣ<br />
ﻞﻣﺎﮐ یﺯﺎﺳﺍﺪﺟ ﻪﺑ ﺭﺩﺎﻗ PFP ﻥﻮﺘﺳ ﻂﻘﻓ ﻪﮐ ﺪﻧﺪﺷ ﻪﺘﻓﺮﮔ ﺭﺎﮐ ﻪﺑ ﻕﻮﻓ ﻩﺩﺎﻣ<br />
.( 3 ﻞﮑﺷ)<br />
ﺕﺎﺒﯿﮐﺮﺗ ﻪﯿﻠﮐ یﺍﺮﺑ یﺮﺘﺸﯿﺑ یﺭﺍﺩﺯﺎﺑ ﺚﻋﺎﺑ<br />
ﺮﺑ ﺕﺎﺒﯿﮐﺮﺗ ﻦﯾﺍ ﺩﺎﯾﺯ<br />
یﺭﺍﺩﺯﺎﺑ . ﺪﻧﻮﺸﯿﻣ ﻞﯿﻨﻓ و<br />
PFP<br />
ﺩﻮﺑ ﻦﯿﻟﺎﺘﻔﻧوﺮﺘﯿﻧ ﻁﻮﻠﺨﻣ<br />
یﺎﻬﻧﻮﺘﺳ ﻉﻮﻤﺠﻣ ﺭﺩ<br />
C18 یﺎﻬﻧﻮﺘﺳ ﻪﺑ ﺖﺒﺴﻧ<br />
ﻢﻫ ﺮﺑ ﻪﺑ ﺖﺒﺴﻧ ﺍﺭ π-π<br />
ﺶﻨﮐ ﻢﻫ ﺮﺑ ﺮﺘﻤﻬﻣ ﺶﻘﻧ ﻝﺎﻤﺘﺣﺍ ﺎﻬﻧﻮﺘﺳ ﻦﯾﺍ یوﺭ<br />
ﺖﻬﺟ . ﺪﻫﺩ ﯽﻣ ﺶﯾﺍﺰﻓﺍ ﮏﯿﺗﺎﺘﺳﺍوﺮﺘﮑﻟﺍ یﺎﻫوﺮﯿﻧ و ﺭﺎﺑ ﻝﺎﻘﺘﻧﺍ ﺶﻨﮐ<br />
ﺭﺩ یﺮﺘﺸﯿﺑ ﺕﺎﻌﻟﺎﻄﻣ ﻪﺑ ﺯﺎﯿﻧ ﺎﻬﻧﻮﺘﺳ ﻦﯾﺍ ﻞﻤﻋ ﻡﺰﯿﻧﺎﮑﻣ ﻞﻣﺎﮐ ﻥﺪﺷ ﻦﺷوﺭ
Change language