2010年第04期 - 中国科学院生物物理研究所

走 进 科 学 家2964-71,2006.10. Lee Y, Chin RK, ChristiansenP, Sun Y, Tumanov AV, Wang J,Chervonsky A, and Fu YX*. Recruitmentand activation of na 觙 ve Tcells inthe isletsbylymphotoxin beta receptordependent tertiary lymphoid structure.Immunity,25:399-409,2006.11. Lo JC, Wang Y, TumanovAV, Bamji M, Yao Z, Reardon, CA,Getz GS, and Fu YX*. Lymphotoxinbeta receptor-dependent control oflipid homeostasis. (see“LIGHT Hitsthe Liver”in Perspectives at the sameissue of Science, highlight in NatureReview Immunology). Science. 316:285-288,2007.12. Krieg, C, Boyman, O, Fu, Y.X.,Kaye, J.Band Tlymphocyte attenuatorregulates CD8+ Tcell-intrinsichomeostasis and memory cell generation.NatureImmunol.8:162-71,2007.13. Zhang, B, Bowerman, N. A,Salama, J. K, Schmidt, H, Spiotto, M.T. Schietinger, A. Yu, P. Fu, YX*.Weichselbaum, R. R. Rowley, D. A.Kranz, D. M. Schreiber, H. Inducedsensitization of tumor stroma leads toeradication of established cancer by Tcells. J. Exp.Med. 204:49-55,2007.14.KimD.,ZhaoJ,AuhS,DuP,Su.L.Tang H,and Fu YX*. Adaptive immunecellstemperinitialinnateresponses.NatureMed.13:1248-1252,2007.15. Zhu M, and FuYX, CoordinatingDevelopment of MedullaryThymic Epithelial Cells. Immunity29:388,2008.16. Wang Y, Koroleva EP,Kruglov AA, Kuprash DV, NedospasovSA,FuYX*, Tumanov AV*(*Shared Corresponding author). LTbRsignalingin intestinal epithelialcells orchestrates innate immune responsesagainst mucosal bacterial infection.Immunity. 2010 Mar 26;32(3):403-13.与 中 科 院 生 物 物 理 研 究 所 研 究员 合 作 的 代 表 性 论 文Xu D, Fu J, Jin L, Zhang H,Zhou C, Zou Z, Zhao JM, Zhang B,ShiM,DingX,TangZ,FuY.-X*,andWang F-S* (*Shared correspondentauthors) Circulating and Liver ResidentCD4CD25 RegulatoryTCellsActively Influence the Antiviral ImmuneResponse and Disease Progressionin Patients with Hepatitis B. J.Immunol,177:739-747,2006.Fu, J, Xu, D, Liu, Z, Shi, M,Zhao, P, Fu, B, Zhang, Z, Yang, H,Zhang, H, Zhou, C, Yao, J, Jin, L,Wang,H,Yang,Y,Fu,YX,Wang,FS.Increased regulatory Tcells correlatewith CD8 T-cell impairment and poorsurvival in hepatocellular carcinomapatients. Gastroenterology132:23282339,2007.Zhang Z, Ji-Yuan Zhang J-Y,WherryJ,JinB,XuB,ZouZ-S,ZhangS-Y,LiB-S,WangH-H,WuH,FuXY,Wang F-S. Dynamic programmeddeath 1 expression by virus-specificCD8 Tcells correlates with the outcomeof acute hepatitis B. Gastroenterology134(7):1938-49,2008.Kim KD, Zhao J, Auh S, Du P,Su. L. Tang H, and Fu YX. Adaptiveimmune cells temper initial innate responses.Nature Med 13:1248-1252,2007 (see commentary entitled“Notso fast: adaptive suppression of innateimmunity”in Nature Medicine (13:1142-1144, 2007) and highlight entitled“T cells calm the storm”by NatureReviewImmunogy.ZhaoJ,KimKD,Yang,XAuhS,Du P, Fu YX and Tang H. Hyper innateresponses in neonates lead to increasedmorbidity and mortality afterinfection. PNAS, USA. 105: 75287533,2008.ZhaoJ.YangX,AuhS.KimKD,Tang H, and Fu YX. Do adaptive immunecells suppress or activate innateimmunity? Trend in Immuno. 30:8-12,2009.ParkSG,JiangZ,MortensonED,Deng Liufu, Radkevich-Brown, O,Yang X, Sattar1, Yang Wang H,Brown NK, Greene M, Liu Y, Tang J,WangS, and Fu YX. The TherapeuticEffect of Anti-HER2/neu AntibodyDepends on Both Innate and AdaptiveImmunity.CancerCell(Inpress).LiJ,LiY,JinR,YaoJ-Y,ZhouH,Zhu MZ, Fu WX, Qian XP, Zhang J,ZhangY,FuYX,WuL,ChenWFDevelopmentalpathway of CD4+CD8-medullary thymocytes during mouseontogeny and its developmental defectinAire-/-mice.PNAS,USA.104:1817518180,2007.Fan Z, Yu P, Wang Y, Lee Y,WangY,FuM,LiuW,SunY,FuYX.Natural killer activation by LIGHTtriggers tumor specific CD8+ T cellimmunityatthe tumor site to reject establishedtumors. ?Blood,USA. 107:1342-1351,2006.38PDF 文 件 使 用 "pdfFactory Pro" 试 用 版 本 创 建 www.fineprint.cn