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<strong>GIFT</strong>-Report<br />

<strong>MSG</strong> – <strong>Glutamat</strong> – Geschmacksverstärker<br />

Wo findet man <strong>Glutamat</strong> und <strong>MSG</strong> - Geschmacksverstärker<br />

In der Industriefachsprache wird auch von einem fünften Geschmack gesprochen, der nichts anderes<br />

ist als das Ergebnis des Geschmacksverstärkers <strong>MSG</strong>.<br />

Der Name des fünften Geschmacks stammt aus dem Japanischen:<br />

„umami“ bedeutet ungefähr „fleischig“ oder „herzhaft“. Speisen, die „umami“ schmecken,<br />

fallen jedem sofort ein: Parmesankäse, Lasagne, Bouillon, Tomatensaft, Sardinen, Makrelen<br />

und Thunfisch.<br />

Mononatriumglutamat (<strong>MSG</strong>), Dinatriuminosinat (DSI) und Dinatriumguanylat (DSG), wobei<br />

<strong>MSG</strong> die wichtigste Rolle spielt. Im europäischen System der Nahrungsmittel-Zusatzstoffe<br />

(„E-Nummern“) ist <strong>MSG</strong> als E 621 aufgeführt. DSI, dem vorläufig die Nummer E 631 zugeteilt<br />

wurde, ist die zweitwichtigste Umami-Substanz und ist besonders reichlich in Sardinen,<br />

Bonito, Makrelen, Thunfisch und Schweinefleisch enthalten. DSG, die dritte Umami-<br />

Komponente, wurde als solche erst 1960 von Dr. Akira Kuninaka erkannt und kommt vor<br />

allem in Pilzen wie Shiitake, Matsutake, Enokitake und Trüffeln vor.<br />

Man kaufe nichts mit <strong>Glutamat</strong>, Geschmacksverstärker oder E-Nummern der 600er-Serie<br />

(auch "E605" ist ein Nervengift), Kaliumglutamat, Calciumglutamat, oder Glutaminsäure.<br />

Guanylat wirkt noch eine Zehnerpotenz stärker als <strong>Glutamat</strong> - Finger weg!<br />

Man kaufe nichts, was mit "Würz-" beginnt oder so etwas enthält. (Würze, Würzsalz, Würzsoße,<br />

Würzstoff, Würzmittel etc. Auch Sojasoße ist "Würze". "Würze" ist eine beliebige Substanz zum<br />

geschmacklichen Aufpeppen – und normalerweise glutamathaltig. Da "Würze" als Synonym für<br />

Geschmacksverstärker gilt, muss dieser auf Würzsoßen nicht extra ausgewiesen sein.<br />

Man kaufe keine Fertignahrung uneindeutiger Zusammensetzung. Die Inhaltsstoffe von Zutaten<br />

müssen nämlich nicht genannt sein. ("Mit Pizzasoße","mit Salamischeiben","mit Ketchup" usw. – hier<br />

kann alles Mögliche drin sein).<br />

Weil die Vokabel <strong>Glutamat</strong> in der Bio-Sphäre einen schlechten Klang hat, taucht sie dort nicht auf<br />

dem Etikett auf. Das <strong>Glutamat</strong> ist dort getarnt, in den Bio-Suppenwürfeln des Ökoriesen etwa als<br />

"Hefeextrakt". In der "Klaren Suppe", wie die Firma auf Nachfrage mitteilte, seien 2,7 Prozent<br />

<strong>Glutamat</strong> enthalten, im Brühwürfel ("salzarm") 4,9 Prozent. Lustigerweise enthält die Gemüsebrühe<br />

der Firma Rapunzel gar den Hinweis: "Ganz ohne zugesetzte Geschmacksverstärker" - trotz <strong>Glutamat</strong><br />

unterm Tarnkäpplein des Hefeextrakts.<br />

www.giftig.me Seite 1


VERSTECKTES FREIES GLUTAMAT:<br />

DIE GÄNGIGSTEN “CODENAMEN”<br />

Hinter den folgenden E-Nummern verbergen sich <strong>Glutamat</strong>e:<br />

E620 – Glutaminsäure<br />

E621 – Mononatriumglutamat (engl. monosodium glutamate)<br />

E622 – Monokaliumglutamat (engl. monopotassium glutamate)<br />

E623 – Calciumglutamat<br />

E624 – Monoammoniumglutamat<br />

E625 – Magnesiumglutamat<br />

Diese Bezeichnungen gelten allerdings nur für <strong>Glutamat</strong>e in “Reinform” (>99 %). Substanzen,<br />

die weniger als 99 % enthalten, werden unter unzähligen anderen Namen verarbeitet.<br />

Zutaten, die IMMER <strong>Glutamat</strong> enthalten (ca. 30-80 %):<br />

Hefeextrakt<br />

autolysierte Hefe<br />

hydrolysierte (Pflanzen-/Gemüse-) Proteine<br />

hydrolysiertes Hafermehl<br />

Pflanzenproteinextrakt<br />

Natriumkaseinat<br />

Calciumkaseinat<br />

texturierte (Soja-/Gemüse-) Proteine (TVP‘s)<br />

Zutaten, die SEHR OFT <strong>Glutamat</strong> enthalten (ca. 10-40 %):<br />

Malzextrakt<br />

Maltodextrin/Maltodextrose<br />

fermentierter Weizen<br />

(natürliche) Aromen<br />

(pflanzliche/flüssige/Speise-/Fleisch-/Soja-) Würze/Gewürze<br />

gekörnte Brühe<br />

Brühwürfel<br />

Zutaten, die <strong>Glutamat</strong> enthalten KÖNNEN (bis zu 12 %):<br />

Carrageenan<br />

Enzyme<br />

(konzentrierte/isolierte) Weizen-/Sojaproteine<br />

Sojamilch<br />

Pektin<br />

Lecithin<br />

www.giftig.me Seite 2


Unternehmen die freies <strong>Glutamat</strong> <strong>MSG</strong> im großen Stil einsetzen<br />

KFC – ist einer der gefährlichsten, ist auch in den <strong>MSG</strong>-Skandal sehr stark verstrickt.<br />

Burger King – sehr viele Produkte<br />

McDonald‘s – viele Produkte<br />

Nestle – einige Produkte<br />

Pizza Hut – viele Produkte<br />

Umami Burger – viele Produkte<br />

EINIGE DER <strong>MSG</strong> STUDIEN STUDIEN<br />

Latest <strong>MSG</strong> study in rural China shows that <strong>MSG</strong> contributes to obesity in<br />

humans, regardless of caloric intake and activity.<br />

Ahmad, K. and K. Jahan. Studies on the Preventative and Curative Action of Ascorbic Acid<br />

on the Neurological Toxicity of Monosodium <strong>Glutamat</strong>e. Institute of Nutritional and Food<br />

Science - University of Dhaka.<br />

Aizenman, E., Frosch, M.P., and Lipton, S.A. 1988. Responses Mediated by Excitatory Amino<br />

Acid Receptors in Solitary Retinal Ganglion Cells from Rat. J. Physiol 395: 75-91.<br />

Arbogast, Lydia A. and James L. Voogt. 1990. Sex-Related Alterations in Hypothalamic<br />

Tyrosine Hydroxylase After Neonatal Monosodium <strong>Glutamat</strong>e<br />

Treatment. Neuroendocrinology 52 (5): 460-7.<br />

Arndt, T. et al. 1993. Reduced, Positive Nitrogen Balance and Elevated Plasma Free Fatty<br />

Acid Concentration in Growing, <strong>Glutamat</strong>e-induced Obese Rats. Journal of Experimental<br />

Animal Science 36(1):12-8.<br />

Aschner, M er al. 1990. Interactions of Methylmercury with Rat Primary Astrocyte<br />

Cultures: Inhibition of Rubidium and <strong>Glutamat</strong>e Uptake and Induction of Swelling. Brain<br />

Research 530 (2): 245-50.<br />

Aust, L. et al. 1993. Postprandial Thermogenesis of Rats With <strong>Glutamat</strong>e Induced Obesity<br />

in Relation to Energy Intake. Zeitschrift fur Ernahrungswissenschaft 32(1):71-3.<br />

Banister, E. W. et al. 1978. Effect of High-Pressure Oxygen on Cellular Fine Structure,<br />

Ammonia and <strong>Glutamat</strong>e Metabolism. Underwater Physiology: 215-232.<br />

Barbour, B. et al. 1991. Electrogenic Uptake in <strong>Glutamat</strong>e and Aspartate into Glial Cells<br />

Isolated from the Salamander (Ambystoma) Retina. J Physiol 436: 169-183.<br />

www.giftig.me Seite 3


Bennett, Gary J. 1998. The Role of <strong>Glutamat</strong>e in Chronic Inflammatory Pain and Painful<br />

Peripheral Neuropathies. Speaker, NIH National Meeting. The <strong>Glutamat</strong>e Cascade: Common<br />

Pathways of Central Nervous System Disease States. May3-5, 1998.<br />

Betraan, M.A. et al. 1992. Nitrogen Metabolism in Obesity Induced by Monosodium-L-<br />

<strong>Glutamat</strong>e in Rats. International Journal of Obesity and Related Metabolic<br />

Disorders 16(8):555-64.<br />

Botey, J. et al. 1988. Monosodium <strong>Glutamat</strong>e and Skin Pathology in Pediatric<br />

Allergology. Allergology and Immunopathology 16 (6) 425-428.<br />

Broadwell, R.D. and Sofroniew. 1993. Serum Proteins Bypass the Blood-Brain Fluid Barriers<br />

For Extracellular Entry to the Central Nervous System. Experimental Neurology 120:245-<br />

263.<br />

Bruno, V. et al. 1994. Protective Action of Idebenone Again Excitotoxic Degeneration in<br />

Cultured Cortical Neurons. Neurosci Lett 178: 193-196.<br />

Cammer, W et al. 1990. Reactive Gliosis in the Brains of Lewis Rats with Experimental<br />

Allergic Encephalomyelitis. Journal of Neuroimmunology 27 (2-3): 111-120.<br />

Canfield, P.R. et al. 1992. Aspartame Exacerbates EEG Spike-wave Discharge in Children<br />

with Generalized Absence Epilepsy: A Double-blind Controlled Study. Neurology 42: 1000-<br />

1003.<br />

Cangro, Charles Benjamin. 1986. Immunocytochemical and Biochemical Investigation into<br />

the Distribution and Metabolism of <strong>Glutamat</strong>e and N-acetylaspartylglutamate Along the<br />

Spinal Sensory Axis. Ph.D. dissertation, Georgetown University. Dissertation Abstracts<br />

Online. 47(2B): 4781.<br />

Chan, P.H. et al. 1990. Attenuation of <strong>Glutamat</strong>e-Induced Neuronal Swelling and Toxicity in<br />

Transgenic Mice Overexpressing Human CuZn-Superoxide Dismutase. Acta Neurochir<br />

Suppl 51: 245-7.<br />

Cheung, W. T. et al. 1988. Neonatal Monosodium -L-<strong>Glutamat</strong>e Treatment Reduced<br />

Lipolytic Response of Rat Epididymal Adipose Tissue. General Pharmacology 19 (4): 507-<br />

512.<br />

Cho, Y. and S. Bannai. 1990. Uptake of <strong>Glutamat</strong>e and Cysteine in C-6 Glioma Cells and in<br />

Cultured Astrocytes. Journal of Neurochemistry 55 (6): 2091-7.<br />

Choi, D.W. 1988. <strong>Glutamat</strong>e Neurotoxicity and Diseases of the Nervous System. Neuron 1:<br />

623-634.<br />

Choi, D.W. 1994. <strong>Glutamat</strong>e Receptors and the Induction of Excitotoxic Neuronal<br />

Death. Prog. Brain. Res. 100: 47-51.<br />

www.giftig.me Seite 4


Choi, D. W. 1990. The Role of <strong>Glutamat</strong>e Neurotoxicity in Hypoxic-Ischemic Neuronal<br />

Death. Annual Review of Neuroscience 13:171-182.<br />

Choi, Dennis W. 1998. Manipulating <strong>Glutamat</strong>ergic Neurotransmission for Therapeutic<br />

Gains: The Example of Brain Ischemia. Speaker, NIH National Meeting. The <strong>Glutamat</strong>e<br />

Cascade: Common Pathways of Central Nervous System Disease States. May3-5, 1998.<br />

Conner-Kerr, Teresa Ann. 1992. A Possible Mechanism of Excitotoxicity: Autoregulation of<br />

<strong>Glutamat</strong>e Release from Hippocampal Mossy Fiber Terminals. Ph.D. dissertation, East<br />

Carolina University. Dissertation Abstracts Online. 53(11B): 5571.<br />

Coyle, J.T. and P. Puttfarcken. 1993. Oxidative Stress, <strong>Glutamat</strong>e, and Neurodegenerative<br />

Disorders. Science 262: 689-695.<br />

Danbolt, N.C. 2001. <strong>Glutamat</strong>e Uptake. Progressive Neurobiology 65(1):1-105.<br />

Dawson, R., Jr. and Z. Annau. 1983. A Behavioral Assessment of Arcuate Nucleus Damage<br />

After a Single Injection of Monosodium <strong>Glutamat</strong>e. Neurobehavioral Toxicology and<br />

Teratology 5 (4): 399-406.<br />

Dawson, R., Jr. et al. 1989. Age and Dose Dependent Effects of Neonatal Monosodium<br />

<strong>Glutamat</strong>e (<strong>MSG</strong>) Administration To Female Rats. Neurotoxicol. Teratol. 11 (4) 331-337.<br />

Dawson, R., Jr. et al. 1989. A Pharmacological Anaysis of Food Intake Regulation in Rats<br />

Treated Neonatally with Monosodium L-<strong>Glutamat</strong>e (<strong>MSG</strong>). Pharmacol. Biochem. Behav. 32<br />

(2): 391-398.<br />

Dawson, R., Jr. et al. 1997. Attenuation of Leptin-Mediated Effects by Monosodium<br />

<strong>Glutamat</strong>e (<strong>MSG</strong>)-Induced Arcuate Nucleus Damage. American Journal of Physiology.<br />

De Erausquin, G. A. et al. 1990. Gangliosides Normalize Distorted Single-Cell Intracellular<br />

Free CA Super (2+) Dynamics After Toxic Doses of <strong>Glutamat</strong>e in Cerebellar Granule<br />

Cells.Proceedings of the National Academy of Sciences, USA 87 (20): 8017-8021.<br />

De Groot, A. P. et al. 1988. Induction of Hyperplasia in the Bladder Epithelium of Rats by a<br />

Dietary Excess of Acid or Base: Implications for Toxicity/Carcinogenicity Testing. Food and<br />

Chemical Toxicology 26 (5): 425-434.<br />

De Schutter, Erik, 1997. A New Functional Role for Cerebellar Long Term<br />

Depression. Progress in Brain Research 114:529-542.<br />

Dolnikoff, M. S. et al. 1988. Neonatal Treatment with Monosodium <strong>Glutamat</strong>e Increases<br />

Plasma Corticosterone in Rat. Neuroendocrinology 48 (6): 645-649.<br />

Dolnikoff, M. S. et al. 2001. Decreased Lipolysis and Enhanced Glycerol and Glucose<br />

Utilization by Adipose Tissue Prior to Development of Obesity in Monosodium <strong>Glutamat</strong>e<br />

(<strong>MSG</strong>) treated Rats. Int. Journal of Obesity-Related Metabolic Disorders.<br />

www.giftig.me Seite 5


During, M.J. and Spencer, D.D. 1993. Extracellular Hippocampal <strong>Glutamat</strong>e and<br />

Spontaneous Seizure in the Conscious Human Brain. Lancet 341:1607-0610.<br />

Dzogas, Zoran. 1996. In Vivo Activity of Canine Expiratory Bulbospinal Neurons is<br />

Differentially Affected by two Non-N-Methyl-D-Aspartate Receptor Antagonists. Croatian<br />

Medical Journal 37(1).<br />

Eck, H. P. et al. 1990. Partial Recovery of Lymphocyte Activity in Patients with Colorectal<br />

Carcinoma After Curative Surgical Treatment and Return of Plasma <strong>Glutamat</strong>e<br />

Concentrations to Normal Levels. Journal of Cancer Research and Clinical Oncology 116(6):<br />

648-50.<br />

Erdo, S. L. and M. Schaefer. 1991. Memantine is Highly Potent in Protecting Cortical<br />

Cultures Against Excitotoxic Cell Death Evoked by <strong>Glutamat</strong>e and N Methyl-D-<br />

Aspartate. Eur. Journal of Pharmacology 198 (2-3): 215-218.<br />

Favaron, M. et al. 1990. Down-regulation of Protein Kinase C Protects Cerebellar Granule<br />

Neurons in Primary Culture from <strong>Glutamat</strong>e-Induced Neuronal Death. Proceedings of the<br />

National Academy of Sciences of the United States of America 87 (5): 1983-1987.<br />

Fernandez-Aguado, C. et al. 1989. Liver <strong>Glutamat</strong>e and Glutamine Concentration in<br />

Experimental Hepatocarcinogenesis: Effect of Glutathione. Biochem. Chem. Carcinog.,<br />

(Proc. Satell. Symp. 14th Int. Congr. Biochem. ) pp 203-9<br />

Fernstrom, J.D. 2000. Pituitary Hormone Secretion in Normal Male Humans: Acute<br />

Responses to a Large, Oral Dose of Monosodium <strong>Glutamat</strong>e. Journal of Nutrition 130 (Suppl<br />

4s):1053-7.<br />

Fisher, R. S. 1991. <strong>Glutamat</strong>e and Epilepsy. Frontiers of Clinical Neuroscience 11: 131-146.<br />

Frandsen, A. et al. 1990. Novel <strong>Glutamat</strong>e Antagonists Selectively Protect Against Kainic<br />

Acid Neurotoxicity in Cultured Cerebral Cortex Neurons. Journal of Neurochemistry 55 (5):<br />

1821-1823.<br />

Frandsen, A. and Arne Schousboe. 1991. Dantrolene Prevents <strong>Glutamat</strong>e Cytotoxicity and<br />

Calcium Release From Intracellular Stores in Cultured Cerebral Corical Neurons. Journal of<br />

Neurochemistry 56 (3): 1075-8.<br />

Frankel, Arthur et al. 1990. Role of Arginine 180 and Glutamic Acid 177 of Ricin Toxin A<br />

Chain in Enzymic Inactivation of Ribosomes. Molecular Cell Biology 10 (12) 6257-63.<br />

Freese, A. et al. 1990. Characterization and Mechanism of <strong>Glutamat</strong>e Neurotoxicity in<br />

Primary Striatal Cultures. Brain Research 521 (1-2): 254-264.<br />

Fundytus, M.E., 2001. <strong>Glutamat</strong>e Receptors and Nociception: Implications for the Drug<br />

Treatment of Pain. CNS Drugs 2001 Jan: 15(1): 29-58.<br />

www.giftig.me Seite 6


Furkawa, K. et al. 1997. The Actin-severing Protein Gelsolin Modulates Calcium Channel<br />

and NMDA Receptor Activities and Vulnerability to Excitotoxicity in Hippocampal<br />

Neurons. J. Neurosci17: 8178-8186.<br />

Gao, J. et al. 1994. Transplacental Neurotoxic Effects of Monosodium <strong>Glutamat</strong>e on<br />

Structures and Functions of Specific Brain Areas of Filial Mice. Sheng Li Hsueh Pao Acta<br />

Physiologica Sinica46(1):44-51.<br />

Gray, A.M., Rawls, S.M. Shippenberg, T.S., and McGinty, J.F. 1999. Kappa Opioid Agonist, U-<br />

69593, Decreases Acute Amphetamine-evoked Bahaviors andCalcium-dependent Dialysate<br />

Levels of Dopamine and <strong>Glutamat</strong>e in the Ventral Striatum. J Neurochem 73: 1066-1074.<br />

Greene, James G. 1998. Bioenergeetics and Excitotoxicity: An Examination of Neurotoxicity<br />

Secondary to Succinate Dehydrogenase Inhibition. Ph.D. dissertation. The University of<br />

Rochester. Dissertation Abstracts Online. 59(03B): 0933.<br />

Greenmayre, J. and Porter, R. 1994. Anatomy and Physiology of glutamate in the<br />

CNS. Neurol 44: s7-sl3.<br />

Greenmayre, J. Timothy. 1998. <strong>Glutamat</strong>ergic Mechanisms in the Cause and Treatment of<br />

Parkinson’s Disease. Speaker, NIH National Meeting. The <strong>Glutamat</strong>e Cascade: Common<br />

Pathways of Central Nervous System Disease States. May3-5, 1998.<br />

Hahn, J. S. et al. 1988. Central Mammalian Neurons Normally Resistant to <strong>Glutamat</strong>e<br />

Toxicity Are Made Sensitive by Extracellular Ca Super (2+): Toxicity is blocked by the N-<br />

Methyl-D-Aspartate Antagonist. Proceedings of the National Academy of Sciences USA 85<br />

(17) 6556-6560.<br />

Halpain, S., Hipolito, A. and Saffer, L. 1998. Regulation of F-actin Stability in Dendritic Spines<br />

by <strong>Glutamat</strong>e Receptors and Calcineurin. J Neurosci 18: 9835-9844.<br />

Helton, D.R. et al. 1998. Anxiolytic and Side-Effect Profile of LY354740: A Potent, Highly<br />

Selective, Orally Active Agonist for Group II Metabotropic <strong>Glutamat</strong>e Receptors. Journal of<br />

Pharmacology and Experimental Therapeutics 284(2):651-60.<br />

Himi, T. et al. 1990. Spider Toxin (JSTX-3) Inhibits the Convulsions Induced by <strong>Glutamat</strong>e<br />

Agonists. J. Neural Transm. 80 (2): 95-104.<br />

Hussain, M.M. et al. 1989. Characterization of <strong>Glutamat</strong>e Dehydrogenase Isoproteins<br />

Purified From the Cerebellum of Normal Subjects and Patients with Degenerative<br />

Neurological Disorders, and From Human Neoplastic Cell Lines. Journal of Biol.<br />

Chemistry 264 (34): 20730-735.<br />

Ishikawa, K et al. 1997. Hippocampal Degeneration Inducing Impairment of Learning in<br />

Rats: Model of Dementia? Behavioural Brain Research 83(1-2):39-44.<br />

Janssen, Raelyn et al. 1991. <strong>Glutamat</strong>e Neurotoxicity in the Developing Rat Cochlea:<br />

Physiological and Morphological Approaches. Brain Research 552 (2): 255-64.<br />

www.giftig.me Seite 7


Jensen, Frances E. 1998. Role of <strong>Glutamat</strong>e Receptor Maturation in Perinatal Brain<br />

Injury. Speaker, NIH National Meeting. The <strong>Glutamat</strong>e Cascade: Common Pathways of<br />

Central Nervous System Disease States. May3-5, 1998.<br />

Kato, S. et al. 1990. Gliotoxic Effects of Alpha- Aminodipic Acid Isomers on the Carp Retina:<br />

A Long Term Observation. Neuroscience 36 (1): 145-153.<br />

Kayastha, Arvind M. et al. 1991. Site-Directed Mutagenesis of the Beta Subunit of<br />

Tryptophan Synthase From Salmonella Typhimurium. Role of Active Site Glutamic Acid. J.<br />

Biol. Chem. 266 (12): 7618-25.<br />

Kirchgessner, A. L. et al. 1997. Excitotoxicity in the enteric nervous system. Journal of<br />

Neuroscience 17:8807-8816.<br />

Kiskin, N. I. et al. 1989. Blocking Action of Nephalia Clavata Spider Toxin on Ionic Currents<br />

Activated by <strong>Glutamat</strong>e and its Agonists in Isolated Hippocampal<br />

Neurons. Neurophysiology 21 (2): 110-116.<br />

Klunk, W. E. et al. 1991. L Phosphoserine A Metabolite Elevated in Alzheimer's Disease<br />

Interacts with Specific L <strong>Glutamat</strong>e Receptor Subtypes. Journal of Neurochem 56 (6): 1997-<br />

2003.<br />

Koh, B.K., et al. 1996. Effects of Cysteine on Free Radical Production and Protein<br />

Modification in Extruded Wheat Flour. Cereal Chem 73(1): 115-122.<br />

Koh, Jaeyoung. 1989. <strong>Glutamat</strong>e Receptor-Mediated Neurotoxicity in Murine Neuronal<br />

Cultures. Ph.D. dissertation, Stanford University. Dissertation Abstracts Online 50(12B):<br />

5486.<br />

Kristova, V. et al. 1998. Early Postnatal <strong>Glutamat</strong>e treatment Results in Altered Vascular<br />

Responsiveness to Seratonin and Noradrenaline in Adult Rats. Endocrine<br />

Regulations 32:133-139.<br />

Kubo, T. et al. 1993. Neonatal <strong>Glutamat</strong>e Can Destroy the Hippocampal CA1 Structure and<br />

Impair Discrimination Learning in Rats. Brain Research 616:311-314.<br />

Kurozumi, K. et al. 1990. Generation of Inositol Phosphates, Cytosolic Ca2+, and Secretion<br />

of Noradrenaline in PC12 Cells Treated with <strong>Glutamat</strong>e. FEBS Lett. 270 (1-2): 225-8.<br />

Lipton, S. and Rosenberg, P. 1994. Excitatory Amino Acids as a Final Common Pathway for<br />

Neurologic Disorders. New England Journal of Medicine. 330: 613-622.<br />

Lipton, Stuart A. 1998. Excitotoxic Apoptosis and Necrosis in AIDS Dementia and Stroke:<br />

Potential Treatment with NMDA Open-channel Blockers and Nitric Oxide Related<br />

Species. Speaker, NIDA meeting, The <strong>Glutamat</strong>e Cascade. Brigham and Women’s Hospital<br />

and Harvard Medical School.<br />

www.giftig.me Seite 8


Liu, W. K. et al. 1989. Effects of Neonatal Monosodium-L-<strong>Glutamat</strong>e Treatment on Rat<br />

Alveolar Macrophages. Chemical Biological Interactions 69 (2-3): 193-201.<br />

Liu, M. T. et al. 1999. Identification and characterization of Glucoresponsive Neurons in the<br />

Enteric Nervous System. Journal of Neuroscience 19:10305-10317.<br />

Lovinger, David M. et al. 1990. Ethanol Inhibition of Neuronal <strong>Glutamat</strong>e Receptor<br />

Function. Ann. Med. 22 (4): 247-52.<br />

Lundberg A/S, H. 2002. Data on Ebixa for Treatment of Alzheimer's Disease. H.Lundberg<br />

A/S Press Release #73 Date 22-07-2002<br />

Machado, U. F. et al. 1993. Decreaeed Glucose Transporter GLUT 4 Content in Insulin-<br />

Sensitive Tissues of Obese Aurothioglucose- and Monosodium <strong>Glutamat</strong>e-Treated<br />

Mice. Hormone and Metabolic Research 25(9):462-5.<br />

Magalhaes, J. R. 1989. Ammonium Assimilation in Different Plant Species as Affected by<br />

Nitrogen Form and pH Control in Solution Culture. Fertilizer Research 21 (1): 1-6.<br />

Margarinos, A. M. et al. 1988. Regulation of the Central Nervous System-Pituitary-Adrenal<br />

Axis in Rats After Neonatal Treatment With Monosodium<br />

<strong>Glutamat</strong>e. Neuroendocrinology 48 (2): 105-111.<br />

Marc, R. E. and Lam, D.M.K. 1981. Uptake of Aspartic and Glutamic Acid by Photoreceptors<br />

in Goldrish Retina. Proc. Natl. Acad. Sci. 78: 7185-7189.<br />

Marinez, F. et al. 1993. Neuroexcitatory Amino Acid Levels in Plasma and Cerebrospinal<br />

Fluid During Migraine Attacks. Cephalagia 13(2):89-93.<br />

Maulucci-Gedde, M and D. W. Choi. May 1987. Coritical Neurons Exposed to <strong>Glutamat</strong>e<br />

Rapidly Leak Preloaded Chromium. Experimental Neurology 2: 420-429.<br />

Max, Mitchell B. 1998. Effect of <strong>Glutamat</strong>e Blockers on Human Pain. Speaker, NIDA<br />

meeting, The <strong>Glutamat</strong>e Cascade. Institute of Dental Research, National Institutes of Health.<br />

McDonald, J. W. and M.V Johnston. 1993. Excitatory Amino Acid Neurotoxicity in the<br />

Developing Brain. NIDA Research Monograph 133:185-205.<br />

McMahon, Harvey T. et al. 1990. Alpha-Latrotoxin Releases Both Vesicular and Cytoplasmic<br />

<strong>Glutamat</strong>e From Isolated Nerve Terminals. Journal of Neurochemistry 55 (6) 2039-47.<br />

Miaskowiak, B. and M. Partyka. 1993. Effects of Neonatal Treatment with <strong>MSG</strong><br />

Monosodium <strong>Glutamat</strong>e on Hypothalamo-Pituitary-Thyroid Axis in Adult Male<br />

Rats. Histology and Histopathology8(4):731-4.<br />

Miaskowiak, B. and M. Partyka. 1993. Effect of Perinatal Administration of Monosodium<br />

<strong>Glutamat</strong>e <strong>MSG</strong> on the Reproductive System of the Male Rat. Endokrynologia Polska 44<br />

(4):497-505.<br />

www.giftig.me Seite 9


Michaels, R. L. and S. M. Rothman. 1990. <strong>Glutamat</strong>e Neurotoxicity in Vitro: Antagonist<br />

Pharmacology and Intracellular Calcium Concentrations. Journal of Neuroscience 10 (1):<br />

283-292.<br />

Michaelis, E. K. 1990. <strong>Glutamat</strong>e Receptor Changes in Brain Synaptic Membranes From<br />

Human Alcoholics. Neurochem. Research 15 (11): 1055-63.<br />

Milani, D. et al. 1991. Excitatory Amino-Acid Induced Alterations of Cytoplasmic Free<br />

Calcium in Individual Cerebellar Granule Neurons: Role in Neurotoxicity. J. Neurosci. Res.<br />

28 (3): 434-41.<br />

Miller, S. M. and B. Magasanik. 1990. Role of NAD-Linked <strong>Glutamat</strong>e Dehydrogenase in<br />

Nitrogen Metabolism in Saccharomyces Cerevisiae. Journal of Bacteriology 172(9): 4927-35.<br />

Miyamoto, M et al. 1989. Antioxidants Protect Against <strong>Glutamat</strong>e-Induced Cytotoxicity in a<br />

Neuronal Cell Line. Journal of Pharmacology and Experimental Therapy 250 (3) 1132-1140.<br />

Mohammed, A. K. et al. 1990. Behavioural Deficits and Seratonin Depletion in Adult Rats<br />

After Transient Infant Nasal Viral Infection. Neuroscience 35 (2): 355-63.<br />

Morrison, John H. 1998. <strong>Glutamat</strong>e Receptor Plasticity in the Hippocampus: Implications<br />

for Aging. Speaker, NIDA meeting, The <strong>Glutamat</strong>e Cascade Fishberg Research Center for<br />

Neurobiology and Mount Sinai School of Medicine.<br />

Mural, R. J. et al. 1990. Examination of the Intersubunit Interaction Between <strong>Glutamat</strong>e-48<br />

and Lysine-168 of Ribulose-Bisphosphate Carboxylase/Oxygenase by Site-Directed<br />

Mutagenisis. J. Biol. Chemistry 265(11): 6501-6505.<br />

Murphy, T. H. et al. 1990. Immature Cortical Neurons are Uniquely Sensitive To <strong>Glutamat</strong>e<br />

Toxicity by Inhibition of Cystine Uptake. FASEB Journal 4 (6): 1624-1633.<br />

Murphy, T. H. et al. 1991. Enhanced NAD (P) H:Quinone Reductase Activity Prevents<br />

<strong>Glutamat</strong>e Toxicity Produced by Oxidative Stress. Journal of Neurochemistry 56 (3): 990-<br />

995.<br />

Murphy, T. H et al. 1989. <strong>Glutamat</strong>e Toxicity in a Neuronal Cell Line Involves Inhibition of<br />

Cystine Transport Leading to Oxidative Stress. Neuron 2 (6): 1547-58.<br />

Murphy, T.H. and J. M. Baraban. 1990. <strong>Glutamat</strong>e Toxicity In Immature Cortical Neurons<br />

Precedes Development of <strong>Glutamat</strong>e Receptor Currents. Dev. Brain Research 57 (1): 146-<br />

150.<br />

Mytilineou, C et al. 1997. L-(-)Desmethyiselegeline, a Metabolite of Selegeline (L-(-)-<br />

deprenyl, Protects Mesencephalic Dopamine Neurons From Excitotoxicity in Vitro. J<br />

Neurochem 68: 434-436.<br />

Miyamoto, M. and Coyle J. 1990. Idebenone Attenuates Neuronal Degeneration Induced by<br />

Intrastriatal Injection of Excitotoxins. Exp Neurol 108: 38-45.<br />

www.giftig.me Seite 10


Miyamoto, M. et al. 1989. Antioxidants Protect Against <strong>Glutamat</strong>e-induced Cytotoxicity in<br />

a Neuronal Cell Line. J Pharmacol Exp Ther 250: 1132-1140.<br />

Murphy, Timothy H. 1989. <strong>Glutamat</strong>e Toxicity in a Neuronal Cell Line Involves Inhibition of<br />

Cystine Uptake Leading to Oxidative Stress. Ph.D. dissertation. The Johns Hopkins<br />

University. Dissertation Abstracts Online. 50(07B): 2863.<br />

Nakanishi, Koji, et al. 1990. Philanthotoxin-433 (PHTX-433), A Non-competitive <strong>Glutamat</strong>e<br />

Receptor Inhibitor. Pure Applied Chemistry 62 (7): 1223-30.<br />

Nenoff, P. et al. 1993. In Vivo Assessment of Insulin Binding in Different Organs of Growing<br />

and Adult <strong>Glutamat</strong>e-Induced Obese Rats. Experimental and Clinical<br />

Endocrinology 101(4):215-21.<br />

Nishimura, Atsushi. 1990. Neonatal <strong>Glutamat</strong>e-Induced Cerebral Cortical Degeneration in<br />

Rats. Nichidai Igaku Zasshi 49 (12): 1131-9.<br />

Nowak, L., Bregestovski, P. et al. 1984. Magnesium Gates <strong>Glutamat</strong>e-activated Channels in<br />

Mouse Central Neurones. Nature 307: 462-465.<br />

O' Brien, J. et al. 1984. Toxicity of Maillard Reaction Products of Monosodium <strong>Glutamat</strong>e<br />

and Glucose in Rats. Irish Journal of Food Science and Technology 8 (1): 77.<br />

O' Brien, J. and R. Walker. 1988. Toxicological Effects of Dietary Maillard Reaction Products<br />

in the Rat. Food and Chemical Toxicology 26 (9): 775-784.<br />

O’Hearn, E. and Molliver, M.E. 1999. Neurotoxins and Neuronal Death: An Animal Model of<br />

Excitotoxicity. In V.E. Koliatsos (ed): Cell Death and Diseases of the Nervous System. Totowa,<br />

Humana Press. pp 221-245.<br />

Olney, J. W. and M. T. Price. 1986. Cholinergic Neurotoxicity: Mechanisms and<br />

Prevention. Washington University, St. Louis MO Dept of Psychiatry Annual Report.<br />

Olney, J. et al. 1998. Excitotoxic Neurodegeneration in Alzheimers Disease. Arch Neurol 54:<br />

1234-1240.<br />

Olney, J.W., Wozniak, D.F., Farber, N.B. 1997. Excitotoxic Neurodegeneration in Alzheimer<br />

Disease, New Hypothesis and New Therapeutic Strategies. Arch Neurol Oct: 54(10): 1234-<br />

1240.<br />

Olney, J.W. et al. 1996. Increasing Brain Tumor Rates: Is there a Link to Aspartame? Journal<br />

of Neuropathology and Experimental Neurology 55:1115-23.<br />

Olney, J. W.1994. Excitotoxins in Foods. Neurotoxicology 15:535-44.<br />

Olney, J. W. 1990. Excitotoxin Mediated Neuron Death in Youth and Old Age. Progress in<br />

Brain Research 86:37-51.<br />

www.giftig.me Seite 11


Olney, J. W. 1990. Excitotoxin Amino Acids and Neuropsychiatric Disorders. Annual Review<br />

of Pharmacology and Toxicology 30:47-71.<br />

lney, J. 1989. <strong>Glutamat</strong>e, a Neurotoxic Transmitter. J Child Neurol 4: 218-226.<br />

Olney, J.W. and M.T. Price. 1980. Neuroendocrine Interactions of Excitatory and Inhibitory<br />

Amino Acids. Brain Research Bulletin 5 (Suppl 2): 361-368.<br />

Olney, J. W. et al. 1977. Neurotoxic Effects of <strong>Glutamat</strong>e on Mouse Area Postrema. Brain<br />

Research 120: 151-157.<br />

Olney, J.W. 1974. Toxic Effects of <strong>Glutamat</strong>e and Related Amino Acids on the Developing<br />

Central Nervous System. Inherited Disorders of Amino Acid Metabolism, W. N. Nylan, New<br />

York, Wiley.<br />

Olney, J. W. et al. 1973. Brain-Damaging Potential of Protein Hydrolysates. New England<br />

Journal of Medicine 289: 391-393.<br />

Olney, J. W. et al. 1971. Cytotoxic Effects of Acidic and Sulphur Containing Amino Acids on<br />

the Infant Mouse Central Nervous System. Experimental Brain Research 14:61-76.<br />

Olney, J.W. and O.L. Ho. 1970. Brain Damage in Infant Mice Following Oral Intake of<br />

<strong>Glutamat</strong>e, Aspartate or Cysteine. Nature 227:609-610.<br />

Olney, J.W. 1969. <strong>Glutamat</strong>e-induced retinal degeneration in neonatal mice. Journal of<br />

Neuropathology and Experimental Neurology 28:455-474.<br />

Olney, J.W. 1969. Brain Lesions, Obesity, and Other Disturbances in Mice Treated with<br />

Monosodium <strong>Glutamat</strong>e. Science 164:719-721.<br />

Olney, J. W. and L.G. Sharpe. 1969. Brain Lesions in an Infant Rhesus Monkey Treated With<br />

Monosodium <strong>Glutamat</strong>e. Science 166:386-388.<br />

Orpana, Arto K. 1990. Ethanol-Induced Inhibition of Testosterone Biosynthesis in Rat Leydig<br />

Cells: Role of L-<strong>Glutamat</strong>e and Pyruvate. Journal of Steroid Biochem. 36 (5): 473-8.<br />

Pike, R.N., D. Bagarozzi Jr and J. Travis. 1997. Immunological cross-reactivity of the Major<br />

Allergen from Perennial Ryegrass (Lolium Perenne), L01 pI, and the Cysteine Proteinase,<br />

Bromelain. Int. Arch. Allergy Immunol. 1123: 412-414.<br />

Pol, A. et al (1990). <strong>Glutamat</strong>e, the Dominant Excitatory Transmitter in Neuroendocrine<br />

Regulation. Sci 250: 1276-1278<br />

Portais, J. C. et al. 1991. Magnetic Resonance Spectroscopy and Metabolism. Applications<br />

of Proton and 13C NMR to the Study of <strong>Glutamat</strong>e Metabolism in Cultured Glial Cells and<br />

Human Brain In Vivo. Biochimie 73 (1): 93-7.<br />

www.giftig.me Seite 12


Privat, Alain et al. 1990. Neuronal Protection by Phenycyclidines: In Vitro<br />

Studies. Actual. Chim. Ther. 17: 187-200.<br />

Pulvirenti, Luigi. 1998. <strong>Glutamat</strong>e During the Natural History of Psychostimulant<br />

Dependence: Synaptic Plasticity and Medications Development. Speaker, NIDA meeting,<br />

The <strong>Glutamat</strong>e Cascade. University of Rome – Tor Vergata, Italy.<br />

Rao, G. S. and K. P. Pandya. 1989. Release of 2-Thiobarbituric Acid Reactive Products From<br />

<strong>Glutamat</strong>e or Deoxyribonucleic Acid by 1, 2, 4-Benzenetriol or Hrdroquinone in the<br />

Presence of Copper Ions. Toxicology 59 (1): 59-65.<br />

Rawls, S.M., McGinty, J.F., 1998. Presynaptic Kappa Opioid and Muscarinic Receptors<br />

Inhibit the Calcium-dependent Component of Evoked <strong>Glutamat</strong>e Release from Striatal<br />

Synaptosomes. J Neurochem. 73: 1058-1065.<br />

Rawls, S.M., McGinty, J.F. 1998. Kappa Receptor Activation Attenuates L-trans-PDC-evoked<br />

<strong>Glutamat</strong>e Levels in the Striatum. J Neurochem 70: 626-634.<br />

Rigdon, G. C. et al. 1989. Effect of Perinatal Monosodium <strong>Glutamat</strong>e Administration on<br />

Visual Evoked Potentials of Juvenile and Adult Rats. Neuro-Toxicology and Teratology 11<br />

(2): 121-128.<br />

Roberts, H.J. 1988. Reactions Attributed to Aspartame-containing Products: 551 Cases. J<br />

App Nutr 40: 85-94.<br />

Roberts, H.J. 1995. Aspartame and Headache. Neurology 45: 1631-1633.<br />

Roberts, H.J. 1988. Aspartame (NutraSweet®)-associated Epilepsy. Clin Res 36: 349A.<br />

Roberts, H.J. 1988 Complications Associated with Aspartame (NutraSweet®) in<br />

Diabetes. Clin Res 3: 489A.<br />

Roberts, H.J. 1991. Joint Pain Associated with Aspartame Use. Townsend letter for<br />

Doctors. May: 375-376.<br />

Roberts, H.J., 1993 Aspartame-associated Dry Mouth (Xerostomia). Townsend letter for<br />

Doctors. February: 201-202.<br />

Rochelle, Lori G. et al. 1990. Chlordecone Impairs Sodium-Stimulated l-(3h) <strong>Glutamat</strong>e<br />

Transport and Mobility of 16-Doxyl Stearate in Rat Liver Plasma Vesicles. Toxicol. Appl.<br />

Pharacol. 105 (2): 234-42.<br />

Rogawski, Michael E. 1998. <strong>Glutamat</strong>e Neurotransmission in Epilepsy: New Treatment<br />

Strategies. Speaker, NIDA meeting, The <strong>Glutamat</strong>e Cascade. National Institute of<br />

Neurological Disorders and stroke, National Institutes of Health.<br />

www.giftig.me Seite 13


Rosenberg, P.A., and E. Aizenman. 1989. Hundred-fold Increase in Neuronal Vulnerability to<br />

<strong>Glutamat</strong>e Toxicity in Astrocyte-Poor Cultures of Rat Cerebral Cortex. Neuroscience<br />

Letters 103 (2): 162-168. 116 (3) 399.<br />

Rothstein, J.D. et al. 1992. Decreased <strong>Glutamat</strong>e Transport by the Brain and Spinal Cord in<br />

Amyotropic Lateral Sclerosis. New England Journal of Medicine 326:1464-1468.<br />

Ruijter, J. M. and R. E. Baker. 1990. The Effects of Potassium-Induced Depolarization,<br />

<strong>Glutamat</strong>e Receptor Antagonists and N-Methyl-D-Aspartate on Neuronal Survival in<br />

Cultured Neocortex Explants. Int. J. Dev. Neurosci. 8 (4): 361-70.<br />

Sanico, Alvin, et al. 2000. Researchers Present New Theory for Allergic Diseases. American<br />

Journal of Respiratory and Critical Care Medicine.<br />

Schweitzer, L. et al. 1991. <strong>Glutamat</strong>e Neurotoxicity in Rat Auditory System Cochlear<br />

Nuclear Complex. Neurotoxicology Teratol 13 (2): 189-194.<br />

Shapiro, B. H. et al. 1993. Irreversible Suppression of Growth Hormone-Dependent<br />

Cytochrome P450 2C11 in Adult Rats Neonatally Treated with Monosodium<br />

<strong>Glutamat</strong>e. Journal of Pharmacology and Experimental Therapeutics 265(2):979-84.<br />

Shinora, S. et al. 1991. Inhibitory Effect of CCK-8 and Ceruletide on Neuronal Cell Death<br />

Induced by <strong>Glutamat</strong>e and its Possible Mechanism. 64th Annual Meeting of the Japanese<br />

Pharmacological Society 55 (Suppl. 1): 303.<br />

Siegal, T. et al. 1990. Experimental Neoplastic Spinal Cord Compression: Effect of Anti-<br />

Inflammatory Agents and <strong>Glutamat</strong>e Receptor Antagonists on Vascular<br />

Permeability. Neurosurgery 26 (6): 967-70.<br />

Simantov, R. 1989. <strong>Glutamat</strong>e Neurotoxicity in Culture Depends on the Presence of<br />

Glutamine: Implications for the Role of Glial Cells in Normal and Pathological Brain<br />

Development. Journal of Neurochemistry 52 (6): 1694-9.<br />

Singh, J. et al. 1990. Effect of Aspartate and <strong>Glutamat</strong>e on Carbon Tetrachloride Induced<br />

Liver Damage in Rats. Indian Journal of Experimental Biology 28 (12): 1180-3.<br />

Smith, J.D. et al. 2001. Relief of Fibromyalgia Symptoms Following Discontinuation of<br />

Dietary Excitotoxins. Annals of Pharmacotherapy 35(6):702-6.<br />

Solimena, M et al. 1990. Auto-antibodies to GABA-ergic Neurons and Pancreatic Cells in<br />

Stiff-man Syndrome. New England Journal of Medicine 322:1555-1560.<br />

Sorg, O. et al. 1997. Inhibition of Astrocyte <strong>Glutamat</strong>e Uptake by Reactive Oxygen Species:<br />

Role of Antioxidant Enzymes. Mol. Med 7: 431-440.<br />

Sucher, N.J. et al. 1991. Calcium Channel Antagonists Attenuate NMDA Receptor-Mediated<br />

Neurotoxicity of Retinal Ganglion Cells in Culture. Brain Research 551 (1-2): 297-302.<br />

www.giftig.me Seite 14


Summers, M.J. 1995. Administration of <strong>Glutamat</strong>e Following a Reminder Induces Transient<br />

Memory Loss in Day-old Chicks. Brain Research 3(1):1-8.<br />

Tamura, Y. et al. 1991. Ifenprodil-Induced Protection Against <strong>Glutamat</strong>e Cytotoxicity in<br />

Primary Culture of Cortical Neurons. 64th Annual Meeting of the Japanese Pharmacological<br />

Society 55 (Suppl. 1): 297.<br />

Tang-Christensen, M. et al. 1998. Glucagon-like Peptide 1 7-36 amide's Central Inhibition of<br />

Feeding and Peripheral Inhibition of Drinking Are Abolished by Neonatal Monosodium<br />

<strong>Glutamat</strong>e Treatment. Diabetes 47(4):530-7<br />

Tarkowski, S. 1974. Activity of <strong>Glutamat</strong>e Decarboxylase in the Brain of Rats Exposed to<br />

Carbon Disulfide. International Archiv Fuer Arbeitsmedizin 33 (1) 79-82.<br />

Teal, G.E. et al. 1998. Increased <strong>Glutamat</strong>ergic Neurotransmission and Oxidative Stress<br />

After Alcohol Withdrawal. Am J Psychiat 155: 726-732.<br />

Terrian, David, M. et al. 1991. Domoic Acid Enhances the Potassium-Evoked Release of<br />

Endogenous <strong>Glutamat</strong>e From Guinea Pig Hippocampal Mossy Fiber Synaptosomes. Brain<br />

Research 551 (1-2): 303-7.<br />

Tomita, M et al. 1990. Ionic Concentration of Shifting Fluid During <strong>Glutamat</strong>e-Induced<br />

Swelling of Cultured Glioma Cells Estimated by the Cytocrit Technique. Adv. Neurology 52:<br />

558.<br />

Tzimagiorgis, G. et al. 1991. Chromosomal Mapping of <strong>Glutamat</strong>e Dehydrogenase Gene<br />

Sequences to Mouse Chromosomes 7 and 14. Genomics 10 (1) 83-8.<br />

Villalobos, Carlos et al. 1996. Functional <strong>Glutamat</strong>e Receptors in a Subpopulation of<br />

Anterior Pituitary Cells. FASEB J. 10: 654-660.<br />

Vornov, J. J. and J. T. Coyle. 1991. <strong>Glutamat</strong>e Neurotoxicity and the Inhibition of Protein<br />

Synthesis in the Hippocampal Slice. Journal of Neurochemistry 56 (3): 996-1006.<br />

Walling, Anne D. Predicting Which Strokes Will Progress: <strong>Glutamat</strong>e Levels. 1997. American<br />

Family Physician: 55(7): 2532(1).<br />

Wang, J.Q., McGinty, J.F. 1999. <strong>Glutamat</strong>e-dopamine Interactions Mediate the Effects of<br />

Psychostimulant Drugs. Addiction Biology. 4: 143-152.<br />

Weeing-Verhoeff, E. J. D. et al. 1990. Involvement of Aspartic and Glutamic Residues in<br />

Kringle-2 of Tissue-Type Plasminogen activator in Lysine Binding, Fibrin Binding and<br />

Stimulation of Activity as Revealed by Chemical Modification and Oligonucleotide-Directed<br />

Mutagenesis. Protein Engineering 4 (2) 191-8.<br />

Whetsell, W. and Shapira, N. 1993. Biology of Disease. Neuroexcitation, Excitotoxicity and<br />

Human Neurological Disease. Lab Invest 68: 372-387.<br />

www.giftig.me Seite 15


Wolf, Marina E. 1998. <strong>Glutamat</strong>e-Mediated Neuroplasticity: Role in Amphetamine<br />

Addiction. Speaker, NIDA meeting, The <strong>Glutamat</strong>e Cascade. The Chicago Medical School.<br />

Wong, C. C. et al. 1988. Effect of Neonatal Monosodium-L-<strong>Glutamat</strong>e Treatment on the<br />

Response of Isolated Uterine Preparation To Various Uterine Contraction Stimulators. Gen.<br />

Pharmacol.19 (5): 673-677.<br />

Wong, P.T. et al. 1997. Deficits in Water Escape Performance and Alterations in<br />

Hippocampal Cholinergic Mechanisms Associated with Neonatal Monosodium <strong>Glutamat</strong>e<br />

Treatment in Mice.Pharmacology, Biochemistry and Behaviour 57(1-2):383-8.<br />

Xu, C. J. et al. 1997. Effect of Phosphomonoesters, Phosphodiesters, and PhosphoCreatine<br />

on <strong>Glutamat</strong>e Uptake by Synaptic Vesicles. Molecular and Chemical Neuropathology 32(1-<br />

3):89-99.<br />

Yamamoto, T, et al. 1993. Plasma Levels of Insulin-like Growth Factor-I are Reduced at one<br />

Week of Age in Monosodium L-<strong>Glutamat</strong>e-Treated Mice. Endocrine Journal 40(4):461-5.<br />

Yanai, A. et al. 1991. 4-0 Methylpyridoxine-Induced Convulsion Accompanied by a<br />

Decreased Cerebral GABA Level in Guinea Pigs. 64th Annual Meeting of the Japanese<br />

Pharmacological Society55 (Suppl. 1): 303.<br />

Yokota, I. et al. 1990. Molecular Basis of Medium Chain Acyl-Coenzyme A Dehydrogenase<br />

Deficiency. An A to G Transition at Position 985 That Causes a Lysine-304 to <strong>Glutamat</strong>e<br />

Substitution in the Mature Protein is the Single Prevalent Mutation. J. Clinical Invest. 86 (3):<br />

1000-1003.<br />

Yu, T. et al. 1997. Effects of Maternal Oral Administration of Monosodium <strong>Glutamat</strong>e at a<br />

Late Stage of Pregnancy on Developing Mouse Fetal Brain. Brain Research 747(2):195-206.<br />

Zeevalk, G. D. and W. J. Nicklas. 1990. Chemically Induced Hypoglycemia and Anoxia:<br />

Relationship To <strong>Glutamat</strong>e Receptor-Mediated Toxicity in Retina. J. Pharmacology and<br />

Experimental Therapy 253 (3): 1285-1292.<br />

Zharikov, S. I. et al. 1990. Effect of Alpha-Latrotoxin on the Processes of <strong>Glutamat</strong>e Uptake<br />

and Release in Rat Brain Synaptosomes. Biol. Membr. 7(10): 101321<br />

Zhao, X. N. et al. 1990. Morphine Enhancement of <strong>Glutamat</strong>e and Kainic Acid<br />

Neurotoxicity. Met. Ions Biol. Med. Proc. Int. Symp. pp 156-8.<br />

Zieglgansberger, Walter and Planck, M. 1998. Acamprosate, a Novel Anti-craving<br />

Compound Acts Via <strong>Glutamat</strong>ergic Pathways. Speaker, NIDA meeting, The <strong>Glutamat</strong>e<br />

Cascade. Institute of Psychiatry, Munich, Germany.<br />

Zukin, Stephen R. 1998. Schizophrenia: A <strong>Glutamat</strong>ergic Perspective. Speaker, NIDA<br />

meeting, The <strong>Glutamat</strong>e Cascade. National Institute on Drug Abuse, National Institutes of<br />

Health.<br />

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