GIFT-REPORT-Glutamat-MSG.pdf
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<strong>GIFT</strong>-Report<br />
<strong>MSG</strong> – <strong>Glutamat</strong> – Geschmacksverstärker<br />
Wo findet man <strong>Glutamat</strong> und <strong>MSG</strong> - Geschmacksverstärker<br />
In der Industriefachsprache wird auch von einem fünften Geschmack gesprochen, der nichts anderes<br />
ist als das Ergebnis des Geschmacksverstärkers <strong>MSG</strong>.<br />
Der Name des fünften Geschmacks stammt aus dem Japanischen:<br />
„umami“ bedeutet ungefähr „fleischig“ oder „herzhaft“. Speisen, die „umami“ schmecken,<br />
fallen jedem sofort ein: Parmesankäse, Lasagne, Bouillon, Tomatensaft, Sardinen, Makrelen<br />
und Thunfisch.<br />
Mononatriumglutamat (<strong>MSG</strong>), Dinatriuminosinat (DSI) und Dinatriumguanylat (DSG), wobei<br />
<strong>MSG</strong> die wichtigste Rolle spielt. Im europäischen System der Nahrungsmittel-Zusatzstoffe<br />
(„E-Nummern“) ist <strong>MSG</strong> als E 621 aufgeführt. DSI, dem vorläufig die Nummer E 631 zugeteilt<br />
wurde, ist die zweitwichtigste Umami-Substanz und ist besonders reichlich in Sardinen,<br />
Bonito, Makrelen, Thunfisch und Schweinefleisch enthalten. DSG, die dritte Umami-<br />
Komponente, wurde als solche erst 1960 von Dr. Akira Kuninaka erkannt und kommt vor<br />
allem in Pilzen wie Shiitake, Matsutake, Enokitake und Trüffeln vor.<br />
Man kaufe nichts mit <strong>Glutamat</strong>, Geschmacksverstärker oder E-Nummern der 600er-Serie<br />
(auch "E605" ist ein Nervengift), Kaliumglutamat, Calciumglutamat, oder Glutaminsäure.<br />
Guanylat wirkt noch eine Zehnerpotenz stärker als <strong>Glutamat</strong> - Finger weg!<br />
Man kaufe nichts, was mit "Würz-" beginnt oder so etwas enthält. (Würze, Würzsalz, Würzsoße,<br />
Würzstoff, Würzmittel etc. Auch Sojasoße ist "Würze". "Würze" ist eine beliebige Substanz zum<br />
geschmacklichen Aufpeppen – und normalerweise glutamathaltig. Da "Würze" als Synonym für<br />
Geschmacksverstärker gilt, muss dieser auf Würzsoßen nicht extra ausgewiesen sein.<br />
Man kaufe keine Fertignahrung uneindeutiger Zusammensetzung. Die Inhaltsstoffe von Zutaten<br />
müssen nämlich nicht genannt sein. ("Mit Pizzasoße","mit Salamischeiben","mit Ketchup" usw. – hier<br />
kann alles Mögliche drin sein).<br />
Weil die Vokabel <strong>Glutamat</strong> in der Bio-Sphäre einen schlechten Klang hat, taucht sie dort nicht auf<br />
dem Etikett auf. Das <strong>Glutamat</strong> ist dort getarnt, in den Bio-Suppenwürfeln des Ökoriesen etwa als<br />
"Hefeextrakt". In der "Klaren Suppe", wie die Firma auf Nachfrage mitteilte, seien 2,7 Prozent<br />
<strong>Glutamat</strong> enthalten, im Brühwürfel ("salzarm") 4,9 Prozent. Lustigerweise enthält die Gemüsebrühe<br />
der Firma Rapunzel gar den Hinweis: "Ganz ohne zugesetzte Geschmacksverstärker" - trotz <strong>Glutamat</strong><br />
unterm Tarnkäpplein des Hefeextrakts.<br />
www.giftig.me Seite 1
VERSTECKTES FREIES GLUTAMAT:<br />
DIE GÄNGIGSTEN “CODENAMEN”<br />
Hinter den folgenden E-Nummern verbergen sich <strong>Glutamat</strong>e:<br />
E620 – Glutaminsäure<br />
E621 – Mononatriumglutamat (engl. monosodium glutamate)<br />
E622 – Monokaliumglutamat (engl. monopotassium glutamate)<br />
E623 – Calciumglutamat<br />
E624 – Monoammoniumglutamat<br />
E625 – Magnesiumglutamat<br />
Diese Bezeichnungen gelten allerdings nur für <strong>Glutamat</strong>e in “Reinform” (>99 %). Substanzen,<br />
die weniger als 99 % enthalten, werden unter unzähligen anderen Namen verarbeitet.<br />
Zutaten, die IMMER <strong>Glutamat</strong> enthalten (ca. 30-80 %):<br />
Hefeextrakt<br />
autolysierte Hefe<br />
hydrolysierte (Pflanzen-/Gemüse-) Proteine<br />
hydrolysiertes Hafermehl<br />
Pflanzenproteinextrakt<br />
Natriumkaseinat<br />
Calciumkaseinat<br />
texturierte (Soja-/Gemüse-) Proteine (TVP‘s)<br />
Zutaten, die SEHR OFT <strong>Glutamat</strong> enthalten (ca. 10-40 %):<br />
Malzextrakt<br />
Maltodextrin/Maltodextrose<br />
fermentierter Weizen<br />
(natürliche) Aromen<br />
(pflanzliche/flüssige/Speise-/Fleisch-/Soja-) Würze/Gewürze<br />
gekörnte Brühe<br />
Brühwürfel<br />
Zutaten, die <strong>Glutamat</strong> enthalten KÖNNEN (bis zu 12 %):<br />
Carrageenan<br />
Enzyme<br />
(konzentrierte/isolierte) Weizen-/Sojaproteine<br />
Sojamilch<br />
Pektin<br />
Lecithin<br />
www.giftig.me Seite 2
Unternehmen die freies <strong>Glutamat</strong> <strong>MSG</strong> im großen Stil einsetzen<br />
KFC – ist einer der gefährlichsten, ist auch in den <strong>MSG</strong>-Skandal sehr stark verstrickt.<br />
Burger King – sehr viele Produkte<br />
McDonald‘s – viele Produkte<br />
Nestle – einige Produkte<br />
Pizza Hut – viele Produkte<br />
Umami Burger – viele Produkte<br />
EINIGE DER <strong>MSG</strong> STUDIEN STUDIEN<br />
Latest <strong>MSG</strong> study in rural China shows that <strong>MSG</strong> contributes to obesity in<br />
humans, regardless of caloric intake and activity.<br />
Ahmad, K. and K. Jahan. Studies on the Preventative and Curative Action of Ascorbic Acid<br />
on the Neurological Toxicity of Monosodium <strong>Glutamat</strong>e. Institute of Nutritional and Food<br />
Science - University of Dhaka.<br />
Aizenman, E., Frosch, M.P., and Lipton, S.A. 1988. Responses Mediated by Excitatory Amino<br />
Acid Receptors in Solitary Retinal Ganglion Cells from Rat. J. Physiol 395: 75-91.<br />
Arbogast, Lydia A. and James L. Voogt. 1990. Sex-Related Alterations in Hypothalamic<br />
Tyrosine Hydroxylase After Neonatal Monosodium <strong>Glutamat</strong>e<br />
Treatment. Neuroendocrinology 52 (5): 460-7.<br />
Arndt, T. et al. 1993. Reduced, Positive Nitrogen Balance and Elevated Plasma Free Fatty<br />
Acid Concentration in Growing, <strong>Glutamat</strong>e-induced Obese Rats. Journal of Experimental<br />
Animal Science 36(1):12-8.<br />
Aschner, M er al. 1990. Interactions of Methylmercury with Rat Primary Astrocyte<br />
Cultures: Inhibition of Rubidium and <strong>Glutamat</strong>e Uptake and Induction of Swelling. Brain<br />
Research 530 (2): 245-50.<br />
Aust, L. et al. 1993. Postprandial Thermogenesis of Rats With <strong>Glutamat</strong>e Induced Obesity<br />
in Relation to Energy Intake. Zeitschrift fur Ernahrungswissenschaft 32(1):71-3.<br />
Banister, E. W. et al. 1978. Effect of High-Pressure Oxygen on Cellular Fine Structure,<br />
Ammonia and <strong>Glutamat</strong>e Metabolism. Underwater Physiology: 215-232.<br />
Barbour, B. et al. 1991. Electrogenic Uptake in <strong>Glutamat</strong>e and Aspartate into Glial Cells<br />
Isolated from the Salamander (Ambystoma) Retina. J Physiol 436: 169-183.<br />
www.giftig.me Seite 3
Bennett, Gary J. 1998. The Role of <strong>Glutamat</strong>e in Chronic Inflammatory Pain and Painful<br />
Peripheral Neuropathies. Speaker, NIH National Meeting. The <strong>Glutamat</strong>e Cascade: Common<br />
Pathways of Central Nervous System Disease States. May3-5, 1998.<br />
Betraan, M.A. et al. 1992. Nitrogen Metabolism in Obesity Induced by Monosodium-L-<br />
<strong>Glutamat</strong>e in Rats. International Journal of Obesity and Related Metabolic<br />
Disorders 16(8):555-64.<br />
Botey, J. et al. 1988. Monosodium <strong>Glutamat</strong>e and Skin Pathology in Pediatric<br />
Allergology. Allergology and Immunopathology 16 (6) 425-428.<br />
Broadwell, R.D. and Sofroniew. 1993. Serum Proteins Bypass the Blood-Brain Fluid Barriers<br />
For Extracellular Entry to the Central Nervous System. Experimental Neurology 120:245-<br />
263.<br />
Bruno, V. et al. 1994. Protective Action of Idebenone Again Excitotoxic Degeneration in<br />
Cultured Cortical Neurons. Neurosci Lett 178: 193-196.<br />
Cammer, W et al. 1990. Reactive Gliosis in the Brains of Lewis Rats with Experimental<br />
Allergic Encephalomyelitis. Journal of Neuroimmunology 27 (2-3): 111-120.<br />
Canfield, P.R. et al. 1992. Aspartame Exacerbates EEG Spike-wave Discharge in Children<br />
with Generalized Absence Epilepsy: A Double-blind Controlled Study. Neurology 42: 1000-<br />
1003.<br />
Cangro, Charles Benjamin. 1986. Immunocytochemical and Biochemical Investigation into<br />
the Distribution and Metabolism of <strong>Glutamat</strong>e and N-acetylaspartylglutamate Along the<br />
Spinal Sensory Axis. Ph.D. dissertation, Georgetown University. Dissertation Abstracts<br />
Online. 47(2B): 4781.<br />
Chan, P.H. et al. 1990. Attenuation of <strong>Glutamat</strong>e-Induced Neuronal Swelling and Toxicity in<br />
Transgenic Mice Overexpressing Human CuZn-Superoxide Dismutase. Acta Neurochir<br />
Suppl 51: 245-7.<br />
Cheung, W. T. et al. 1988. Neonatal Monosodium -L-<strong>Glutamat</strong>e Treatment Reduced<br />
Lipolytic Response of Rat Epididymal Adipose Tissue. General Pharmacology 19 (4): 507-<br />
512.<br />
Cho, Y. and S. Bannai. 1990. Uptake of <strong>Glutamat</strong>e and Cysteine in C-6 Glioma Cells and in<br />
Cultured Astrocytes. Journal of Neurochemistry 55 (6): 2091-7.<br />
Choi, D.W. 1988. <strong>Glutamat</strong>e Neurotoxicity and Diseases of the Nervous System. Neuron 1:<br />
623-634.<br />
Choi, D.W. 1994. <strong>Glutamat</strong>e Receptors and the Induction of Excitotoxic Neuronal<br />
Death. Prog. Brain. Res. 100: 47-51.<br />
www.giftig.me Seite 4
Choi, D. W. 1990. The Role of <strong>Glutamat</strong>e Neurotoxicity in Hypoxic-Ischemic Neuronal<br />
Death. Annual Review of Neuroscience 13:171-182.<br />
Choi, Dennis W. 1998. Manipulating <strong>Glutamat</strong>ergic Neurotransmission for Therapeutic<br />
Gains: The Example of Brain Ischemia. Speaker, NIH National Meeting. The <strong>Glutamat</strong>e<br />
Cascade: Common Pathways of Central Nervous System Disease States. May3-5, 1998.<br />
Conner-Kerr, Teresa Ann. 1992. A Possible Mechanism of Excitotoxicity: Autoregulation of<br />
<strong>Glutamat</strong>e Release from Hippocampal Mossy Fiber Terminals. Ph.D. dissertation, East<br />
Carolina University. Dissertation Abstracts Online. 53(11B): 5571.<br />
Coyle, J.T. and P. Puttfarcken. 1993. Oxidative Stress, <strong>Glutamat</strong>e, and Neurodegenerative<br />
Disorders. Science 262: 689-695.<br />
Danbolt, N.C. 2001. <strong>Glutamat</strong>e Uptake. Progressive Neurobiology 65(1):1-105.<br />
Dawson, R., Jr. and Z. Annau. 1983. A Behavioral Assessment of Arcuate Nucleus Damage<br />
After a Single Injection of Monosodium <strong>Glutamat</strong>e. Neurobehavioral Toxicology and<br />
Teratology 5 (4): 399-406.<br />
Dawson, R., Jr. et al. 1989. Age and Dose Dependent Effects of Neonatal Monosodium<br />
<strong>Glutamat</strong>e (<strong>MSG</strong>) Administration To Female Rats. Neurotoxicol. Teratol. 11 (4) 331-337.<br />
Dawson, R., Jr. et al. 1989. A Pharmacological Anaysis of Food Intake Regulation in Rats<br />
Treated Neonatally with Monosodium L-<strong>Glutamat</strong>e (<strong>MSG</strong>). Pharmacol. Biochem. Behav. 32<br />
(2): 391-398.<br />
Dawson, R., Jr. et al. 1997. Attenuation of Leptin-Mediated Effects by Monosodium<br />
<strong>Glutamat</strong>e (<strong>MSG</strong>)-Induced Arcuate Nucleus Damage. American Journal of Physiology.<br />
De Erausquin, G. A. et al. 1990. Gangliosides Normalize Distorted Single-Cell Intracellular<br />
Free CA Super (2+) Dynamics After Toxic Doses of <strong>Glutamat</strong>e in Cerebellar Granule<br />
Cells.Proceedings of the National Academy of Sciences, USA 87 (20): 8017-8021.<br />
De Groot, A. P. et al. 1988. Induction of Hyperplasia in the Bladder Epithelium of Rats by a<br />
Dietary Excess of Acid or Base: Implications for Toxicity/Carcinogenicity Testing. Food and<br />
Chemical Toxicology 26 (5): 425-434.<br />
De Schutter, Erik, 1997. A New Functional Role for Cerebellar Long Term<br />
Depression. Progress in Brain Research 114:529-542.<br />
Dolnikoff, M. S. et al. 1988. Neonatal Treatment with Monosodium <strong>Glutamat</strong>e Increases<br />
Plasma Corticosterone in Rat. Neuroendocrinology 48 (6): 645-649.<br />
Dolnikoff, M. S. et al. 2001. Decreased Lipolysis and Enhanced Glycerol and Glucose<br />
Utilization by Adipose Tissue Prior to Development of Obesity in Monosodium <strong>Glutamat</strong>e<br />
(<strong>MSG</strong>) treated Rats. Int. Journal of Obesity-Related Metabolic Disorders.<br />
www.giftig.me Seite 5
During, M.J. and Spencer, D.D. 1993. Extracellular Hippocampal <strong>Glutamat</strong>e and<br />
Spontaneous Seizure in the Conscious Human Brain. Lancet 341:1607-0610.<br />
Dzogas, Zoran. 1996. In Vivo Activity of Canine Expiratory Bulbospinal Neurons is<br />
Differentially Affected by two Non-N-Methyl-D-Aspartate Receptor Antagonists. Croatian<br />
Medical Journal 37(1).<br />
Eck, H. P. et al. 1990. Partial Recovery of Lymphocyte Activity in Patients with Colorectal<br />
Carcinoma After Curative Surgical Treatment and Return of Plasma <strong>Glutamat</strong>e<br />
Concentrations to Normal Levels. Journal of Cancer Research and Clinical Oncology 116(6):<br />
648-50.<br />
Erdo, S. L. and M. Schaefer. 1991. Memantine is Highly Potent in Protecting Cortical<br />
Cultures Against Excitotoxic Cell Death Evoked by <strong>Glutamat</strong>e and N Methyl-D-<br />
Aspartate. Eur. Journal of Pharmacology 198 (2-3): 215-218.<br />
Favaron, M. et al. 1990. Down-regulation of Protein Kinase C Protects Cerebellar Granule<br />
Neurons in Primary Culture from <strong>Glutamat</strong>e-Induced Neuronal Death. Proceedings of the<br />
National Academy of Sciences of the United States of America 87 (5): 1983-1987.<br />
Fernandez-Aguado, C. et al. 1989. Liver <strong>Glutamat</strong>e and Glutamine Concentration in<br />
Experimental Hepatocarcinogenesis: Effect of Glutathione. Biochem. Chem. Carcinog.,<br />
(Proc. Satell. Symp. 14th Int. Congr. Biochem. ) pp 203-9<br />
Fernstrom, J.D. 2000. Pituitary Hormone Secretion in Normal Male Humans: Acute<br />
Responses to a Large, Oral Dose of Monosodium <strong>Glutamat</strong>e. Journal of Nutrition 130 (Suppl<br />
4s):1053-7.<br />
Fisher, R. S. 1991. <strong>Glutamat</strong>e and Epilepsy. Frontiers of Clinical Neuroscience 11: 131-146.<br />
Frandsen, A. et al. 1990. Novel <strong>Glutamat</strong>e Antagonists Selectively Protect Against Kainic<br />
Acid Neurotoxicity in Cultured Cerebral Cortex Neurons. Journal of Neurochemistry 55 (5):<br />
1821-1823.<br />
Frandsen, A. and Arne Schousboe. 1991. Dantrolene Prevents <strong>Glutamat</strong>e Cytotoxicity and<br />
Calcium Release From Intracellular Stores in Cultured Cerebral Corical Neurons. Journal of<br />
Neurochemistry 56 (3): 1075-8.<br />
Frankel, Arthur et al. 1990. Role of Arginine 180 and Glutamic Acid 177 of Ricin Toxin A<br />
Chain in Enzymic Inactivation of Ribosomes. Molecular Cell Biology 10 (12) 6257-63.<br />
Freese, A. et al. 1990. Characterization and Mechanism of <strong>Glutamat</strong>e Neurotoxicity in<br />
Primary Striatal Cultures. Brain Research 521 (1-2): 254-264.<br />
Fundytus, M.E., 2001. <strong>Glutamat</strong>e Receptors and Nociception: Implications for the Drug<br />
Treatment of Pain. CNS Drugs 2001 Jan: 15(1): 29-58.<br />
www.giftig.me Seite 6
Furkawa, K. et al. 1997. The Actin-severing Protein Gelsolin Modulates Calcium Channel<br />
and NMDA Receptor Activities and Vulnerability to Excitotoxicity in Hippocampal<br />
Neurons. J. Neurosci17: 8178-8186.<br />
Gao, J. et al. 1994. Transplacental Neurotoxic Effects of Monosodium <strong>Glutamat</strong>e on<br />
Structures and Functions of Specific Brain Areas of Filial Mice. Sheng Li Hsueh Pao Acta<br />
Physiologica Sinica46(1):44-51.<br />
Gray, A.M., Rawls, S.M. Shippenberg, T.S., and McGinty, J.F. 1999. Kappa Opioid Agonist, U-<br />
69593, Decreases Acute Amphetamine-evoked Bahaviors andCalcium-dependent Dialysate<br />
Levels of Dopamine and <strong>Glutamat</strong>e in the Ventral Striatum. J Neurochem 73: 1066-1074.<br />
Greene, James G. 1998. Bioenergeetics and Excitotoxicity: An Examination of Neurotoxicity<br />
Secondary to Succinate Dehydrogenase Inhibition. Ph.D. dissertation. The University of<br />
Rochester. Dissertation Abstracts Online. 59(03B): 0933.<br />
Greenmayre, J. and Porter, R. 1994. Anatomy and Physiology of glutamate in the<br />
CNS. Neurol 44: s7-sl3.<br />
Greenmayre, J. Timothy. 1998. <strong>Glutamat</strong>ergic Mechanisms in the Cause and Treatment of<br />
Parkinson’s Disease. Speaker, NIH National Meeting. The <strong>Glutamat</strong>e Cascade: Common<br />
Pathways of Central Nervous System Disease States. May3-5, 1998.<br />
Hahn, J. S. et al. 1988. Central Mammalian Neurons Normally Resistant to <strong>Glutamat</strong>e<br />
Toxicity Are Made Sensitive by Extracellular Ca Super (2+): Toxicity is blocked by the N-<br />
Methyl-D-Aspartate Antagonist. Proceedings of the National Academy of Sciences USA 85<br />
(17) 6556-6560.<br />
Halpain, S., Hipolito, A. and Saffer, L. 1998. Regulation of F-actin Stability in Dendritic Spines<br />
by <strong>Glutamat</strong>e Receptors and Calcineurin. J Neurosci 18: 9835-9844.<br />
Helton, D.R. et al. 1998. Anxiolytic and Side-Effect Profile of LY354740: A Potent, Highly<br />
Selective, Orally Active Agonist for Group II Metabotropic <strong>Glutamat</strong>e Receptors. Journal of<br />
Pharmacology and Experimental Therapeutics 284(2):651-60.<br />
Himi, T. et al. 1990. Spider Toxin (JSTX-3) Inhibits the Convulsions Induced by <strong>Glutamat</strong>e<br />
Agonists. J. Neural Transm. 80 (2): 95-104.<br />
Hussain, M.M. et al. 1989. Characterization of <strong>Glutamat</strong>e Dehydrogenase Isoproteins<br />
Purified From the Cerebellum of Normal Subjects and Patients with Degenerative<br />
Neurological Disorders, and From Human Neoplastic Cell Lines. Journal of Biol.<br />
Chemistry 264 (34): 20730-735.<br />
Ishikawa, K et al. 1997. Hippocampal Degeneration Inducing Impairment of Learning in<br />
Rats: Model of Dementia? Behavioural Brain Research 83(1-2):39-44.<br />
Janssen, Raelyn et al. 1991. <strong>Glutamat</strong>e Neurotoxicity in the Developing Rat Cochlea:<br />
Physiological and Morphological Approaches. Brain Research 552 (2): 255-64.<br />
www.giftig.me Seite 7
Jensen, Frances E. 1998. Role of <strong>Glutamat</strong>e Receptor Maturation in Perinatal Brain<br />
Injury. Speaker, NIH National Meeting. The <strong>Glutamat</strong>e Cascade: Common Pathways of<br />
Central Nervous System Disease States. May3-5, 1998.<br />
Kato, S. et al. 1990. Gliotoxic Effects of Alpha- Aminodipic Acid Isomers on the Carp Retina:<br />
A Long Term Observation. Neuroscience 36 (1): 145-153.<br />
Kayastha, Arvind M. et al. 1991. Site-Directed Mutagenesis of the Beta Subunit of<br />
Tryptophan Synthase From Salmonella Typhimurium. Role of Active Site Glutamic Acid. J.<br />
Biol. Chem. 266 (12): 7618-25.<br />
Kirchgessner, A. L. et al. 1997. Excitotoxicity in the enteric nervous system. Journal of<br />
Neuroscience 17:8807-8816.<br />
Kiskin, N. I. et al. 1989. Blocking Action of Nephalia Clavata Spider Toxin on Ionic Currents<br />
Activated by <strong>Glutamat</strong>e and its Agonists in Isolated Hippocampal<br />
Neurons. Neurophysiology 21 (2): 110-116.<br />
Klunk, W. E. et al. 1991. L Phosphoserine A Metabolite Elevated in Alzheimer's Disease<br />
Interacts with Specific L <strong>Glutamat</strong>e Receptor Subtypes. Journal of Neurochem 56 (6): 1997-<br />
2003.<br />
Koh, B.K., et al. 1996. Effects of Cysteine on Free Radical Production and Protein<br />
Modification in Extruded Wheat Flour. Cereal Chem 73(1): 115-122.<br />
Koh, Jaeyoung. 1989. <strong>Glutamat</strong>e Receptor-Mediated Neurotoxicity in Murine Neuronal<br />
Cultures. Ph.D. dissertation, Stanford University. Dissertation Abstracts Online 50(12B):<br />
5486.<br />
Kristova, V. et al. 1998. Early Postnatal <strong>Glutamat</strong>e treatment Results in Altered Vascular<br />
Responsiveness to Seratonin and Noradrenaline in Adult Rats. Endocrine<br />
Regulations 32:133-139.<br />
Kubo, T. et al. 1993. Neonatal <strong>Glutamat</strong>e Can Destroy the Hippocampal CA1 Structure and<br />
Impair Discrimination Learning in Rats. Brain Research 616:311-314.<br />
Kurozumi, K. et al. 1990. Generation of Inositol Phosphates, Cytosolic Ca2+, and Secretion<br />
of Noradrenaline in PC12 Cells Treated with <strong>Glutamat</strong>e. FEBS Lett. 270 (1-2): 225-8.<br />
Lipton, S. and Rosenberg, P. 1994. Excitatory Amino Acids as a Final Common Pathway for<br />
Neurologic Disorders. New England Journal of Medicine. 330: 613-622.<br />
Lipton, Stuart A. 1998. Excitotoxic Apoptosis and Necrosis in AIDS Dementia and Stroke:<br />
Potential Treatment with NMDA Open-channel Blockers and Nitric Oxide Related<br />
Species. Speaker, NIDA meeting, The <strong>Glutamat</strong>e Cascade. Brigham and Women’s Hospital<br />
and Harvard Medical School.<br />
www.giftig.me Seite 8
Liu, W. K. et al. 1989. Effects of Neonatal Monosodium-L-<strong>Glutamat</strong>e Treatment on Rat<br />
Alveolar Macrophages. Chemical Biological Interactions 69 (2-3): 193-201.<br />
Liu, M. T. et al. 1999. Identification and characterization of Glucoresponsive Neurons in the<br />
Enteric Nervous System. Journal of Neuroscience 19:10305-10317.<br />
Lovinger, David M. et al. 1990. Ethanol Inhibition of Neuronal <strong>Glutamat</strong>e Receptor<br />
Function. Ann. Med. 22 (4): 247-52.<br />
Lundberg A/S, H. 2002. Data on Ebixa for Treatment of Alzheimer's Disease. H.Lundberg<br />
A/S Press Release #73 Date 22-07-2002<br />
Machado, U. F. et al. 1993. Decreaeed Glucose Transporter GLUT 4 Content in Insulin-<br />
Sensitive Tissues of Obese Aurothioglucose- and Monosodium <strong>Glutamat</strong>e-Treated<br />
Mice. Hormone and Metabolic Research 25(9):462-5.<br />
Magalhaes, J. R. 1989. Ammonium Assimilation in Different Plant Species as Affected by<br />
Nitrogen Form and pH Control in Solution Culture. Fertilizer Research 21 (1): 1-6.<br />
Margarinos, A. M. et al. 1988. Regulation of the Central Nervous System-Pituitary-Adrenal<br />
Axis in Rats After Neonatal Treatment With Monosodium<br />
<strong>Glutamat</strong>e. Neuroendocrinology 48 (2): 105-111.<br />
Marc, R. E. and Lam, D.M.K. 1981. Uptake of Aspartic and Glutamic Acid by Photoreceptors<br />
in Goldrish Retina. Proc. Natl. Acad. Sci. 78: 7185-7189.<br />
Marinez, F. et al. 1993. Neuroexcitatory Amino Acid Levels in Plasma and Cerebrospinal<br />
Fluid During Migraine Attacks. Cephalagia 13(2):89-93.<br />
Maulucci-Gedde, M and D. W. Choi. May 1987. Coritical Neurons Exposed to <strong>Glutamat</strong>e<br />
Rapidly Leak Preloaded Chromium. Experimental Neurology 2: 420-429.<br />
Max, Mitchell B. 1998. Effect of <strong>Glutamat</strong>e Blockers on Human Pain. Speaker, NIDA<br />
meeting, The <strong>Glutamat</strong>e Cascade. Institute of Dental Research, National Institutes of Health.<br />
McDonald, J. W. and M.V Johnston. 1993. Excitatory Amino Acid Neurotoxicity in the<br />
Developing Brain. NIDA Research Monograph 133:185-205.<br />
McMahon, Harvey T. et al. 1990. Alpha-Latrotoxin Releases Both Vesicular and Cytoplasmic<br />
<strong>Glutamat</strong>e From Isolated Nerve Terminals. Journal of Neurochemistry 55 (6) 2039-47.<br />
Miaskowiak, B. and M. Partyka. 1993. Effects of Neonatal Treatment with <strong>MSG</strong><br />
Monosodium <strong>Glutamat</strong>e on Hypothalamo-Pituitary-Thyroid Axis in Adult Male<br />
Rats. Histology and Histopathology8(4):731-4.<br />
Miaskowiak, B. and M. Partyka. 1993. Effect of Perinatal Administration of Monosodium<br />
<strong>Glutamat</strong>e <strong>MSG</strong> on the Reproductive System of the Male Rat. Endokrynologia Polska 44<br />
(4):497-505.<br />
www.giftig.me Seite 9
Michaels, R. L. and S. M. Rothman. 1990. <strong>Glutamat</strong>e Neurotoxicity in Vitro: Antagonist<br />
Pharmacology and Intracellular Calcium Concentrations. Journal of Neuroscience 10 (1):<br />
283-292.<br />
Michaelis, E. K. 1990. <strong>Glutamat</strong>e Receptor Changes in Brain Synaptic Membranes From<br />
Human Alcoholics. Neurochem. Research 15 (11): 1055-63.<br />
Milani, D. et al. 1991. Excitatory Amino-Acid Induced Alterations of Cytoplasmic Free<br />
Calcium in Individual Cerebellar Granule Neurons: Role in Neurotoxicity. J. Neurosci. Res.<br />
28 (3): 434-41.<br />
Miller, S. M. and B. Magasanik. 1990. Role of NAD-Linked <strong>Glutamat</strong>e Dehydrogenase in<br />
Nitrogen Metabolism in Saccharomyces Cerevisiae. Journal of Bacteriology 172(9): 4927-35.<br />
Miyamoto, M et al. 1989. Antioxidants Protect Against <strong>Glutamat</strong>e-Induced Cytotoxicity in a<br />
Neuronal Cell Line. Journal of Pharmacology and Experimental Therapy 250 (3) 1132-1140.<br />
Mohammed, A. K. et al. 1990. Behavioural Deficits and Seratonin Depletion in Adult Rats<br />
After Transient Infant Nasal Viral Infection. Neuroscience 35 (2): 355-63.<br />
Morrison, John H. 1998. <strong>Glutamat</strong>e Receptor Plasticity in the Hippocampus: Implications<br />
for Aging. Speaker, NIDA meeting, The <strong>Glutamat</strong>e Cascade Fishberg Research Center for<br />
Neurobiology and Mount Sinai School of Medicine.<br />
Mural, R. J. et al. 1990. Examination of the Intersubunit Interaction Between <strong>Glutamat</strong>e-48<br />
and Lysine-168 of Ribulose-Bisphosphate Carboxylase/Oxygenase by Site-Directed<br />
Mutagenisis. J. Biol. Chemistry 265(11): 6501-6505.<br />
Murphy, T. H. et al. 1990. Immature Cortical Neurons are Uniquely Sensitive To <strong>Glutamat</strong>e<br />
Toxicity by Inhibition of Cystine Uptake. FASEB Journal 4 (6): 1624-1633.<br />
Murphy, T. H. et al. 1991. Enhanced NAD (P) H:Quinone Reductase Activity Prevents<br />
<strong>Glutamat</strong>e Toxicity Produced by Oxidative Stress. Journal of Neurochemistry 56 (3): 990-<br />
995.<br />
Murphy, T. H et al. 1989. <strong>Glutamat</strong>e Toxicity in a Neuronal Cell Line Involves Inhibition of<br />
Cystine Transport Leading to Oxidative Stress. Neuron 2 (6): 1547-58.<br />
Murphy, T.H. and J. M. Baraban. 1990. <strong>Glutamat</strong>e Toxicity In Immature Cortical Neurons<br />
Precedes Development of <strong>Glutamat</strong>e Receptor Currents. Dev. Brain Research 57 (1): 146-<br />
150.<br />
Mytilineou, C et al. 1997. L-(-)Desmethyiselegeline, a Metabolite of Selegeline (L-(-)-<br />
deprenyl, Protects Mesencephalic Dopamine Neurons From Excitotoxicity in Vitro. J<br />
Neurochem 68: 434-436.<br />
Miyamoto, M. and Coyle J. 1990. Idebenone Attenuates Neuronal Degeneration Induced by<br />
Intrastriatal Injection of Excitotoxins. Exp Neurol 108: 38-45.<br />
www.giftig.me Seite 10
Miyamoto, M. et al. 1989. Antioxidants Protect Against <strong>Glutamat</strong>e-induced Cytotoxicity in<br />
a Neuronal Cell Line. J Pharmacol Exp Ther 250: 1132-1140.<br />
Murphy, Timothy H. 1989. <strong>Glutamat</strong>e Toxicity in a Neuronal Cell Line Involves Inhibition of<br />
Cystine Uptake Leading to Oxidative Stress. Ph.D. dissertation. The Johns Hopkins<br />
University. Dissertation Abstracts Online. 50(07B): 2863.<br />
Nakanishi, Koji, et al. 1990. Philanthotoxin-433 (PHTX-433), A Non-competitive <strong>Glutamat</strong>e<br />
Receptor Inhibitor. Pure Applied Chemistry 62 (7): 1223-30.<br />
Nenoff, P. et al. 1993. In Vivo Assessment of Insulin Binding in Different Organs of Growing<br />
and Adult <strong>Glutamat</strong>e-Induced Obese Rats. Experimental and Clinical<br />
Endocrinology 101(4):215-21.<br />
Nishimura, Atsushi. 1990. Neonatal <strong>Glutamat</strong>e-Induced Cerebral Cortical Degeneration in<br />
Rats. Nichidai Igaku Zasshi 49 (12): 1131-9.<br />
Nowak, L., Bregestovski, P. et al. 1984. Magnesium Gates <strong>Glutamat</strong>e-activated Channels in<br />
Mouse Central Neurones. Nature 307: 462-465.<br />
O' Brien, J. et al. 1984. Toxicity of Maillard Reaction Products of Monosodium <strong>Glutamat</strong>e<br />
and Glucose in Rats. Irish Journal of Food Science and Technology 8 (1): 77.<br />
O' Brien, J. and R. Walker. 1988. Toxicological Effects of Dietary Maillard Reaction Products<br />
in the Rat. Food and Chemical Toxicology 26 (9): 775-784.<br />
O’Hearn, E. and Molliver, M.E. 1999. Neurotoxins and Neuronal Death: An Animal Model of<br />
Excitotoxicity. In V.E. Koliatsos (ed): Cell Death and Diseases of the Nervous System. Totowa,<br />
Humana Press. pp 221-245.<br />
Olney, J. W. and M. T. Price. 1986. Cholinergic Neurotoxicity: Mechanisms and<br />
Prevention. Washington University, St. Louis MO Dept of Psychiatry Annual Report.<br />
Olney, J. et al. 1998. Excitotoxic Neurodegeneration in Alzheimers Disease. Arch Neurol 54:<br />
1234-1240.<br />
Olney, J.W., Wozniak, D.F., Farber, N.B. 1997. Excitotoxic Neurodegeneration in Alzheimer<br />
Disease, New Hypothesis and New Therapeutic Strategies. Arch Neurol Oct: 54(10): 1234-<br />
1240.<br />
Olney, J.W. et al. 1996. Increasing Brain Tumor Rates: Is there a Link to Aspartame? Journal<br />
of Neuropathology and Experimental Neurology 55:1115-23.<br />
Olney, J. W.1994. Excitotoxins in Foods. Neurotoxicology 15:535-44.<br />
Olney, J. W. 1990. Excitotoxin Mediated Neuron Death in Youth and Old Age. Progress in<br />
Brain Research 86:37-51.<br />
www.giftig.me Seite 11
Olney, J. W. 1990. Excitotoxin Amino Acids and Neuropsychiatric Disorders. Annual Review<br />
of Pharmacology and Toxicology 30:47-71.<br />
lney, J. 1989. <strong>Glutamat</strong>e, a Neurotoxic Transmitter. J Child Neurol 4: 218-226.<br />
Olney, J.W. and M.T. Price. 1980. Neuroendocrine Interactions of Excitatory and Inhibitory<br />
Amino Acids. Brain Research Bulletin 5 (Suppl 2): 361-368.<br />
Olney, J. W. et al. 1977. Neurotoxic Effects of <strong>Glutamat</strong>e on Mouse Area Postrema. Brain<br />
Research 120: 151-157.<br />
Olney, J.W. 1974. Toxic Effects of <strong>Glutamat</strong>e and Related Amino Acids on the Developing<br />
Central Nervous System. Inherited Disorders of Amino Acid Metabolism, W. N. Nylan, New<br />
York, Wiley.<br />
Olney, J. W. et al. 1973. Brain-Damaging Potential of Protein Hydrolysates. New England<br />
Journal of Medicine 289: 391-393.<br />
Olney, J. W. et al. 1971. Cytotoxic Effects of Acidic and Sulphur Containing Amino Acids on<br />
the Infant Mouse Central Nervous System. Experimental Brain Research 14:61-76.<br />
Olney, J.W. and O.L. Ho. 1970. Brain Damage in Infant Mice Following Oral Intake of<br />
<strong>Glutamat</strong>e, Aspartate or Cysteine. Nature 227:609-610.<br />
Olney, J.W. 1969. <strong>Glutamat</strong>e-induced retinal degeneration in neonatal mice. Journal of<br />
Neuropathology and Experimental Neurology 28:455-474.<br />
Olney, J.W. 1969. Brain Lesions, Obesity, and Other Disturbances in Mice Treated with<br />
Monosodium <strong>Glutamat</strong>e. Science 164:719-721.<br />
Olney, J. W. and L.G. Sharpe. 1969. Brain Lesions in an Infant Rhesus Monkey Treated With<br />
Monosodium <strong>Glutamat</strong>e. Science 166:386-388.<br />
Orpana, Arto K. 1990. Ethanol-Induced Inhibition of Testosterone Biosynthesis in Rat Leydig<br />
Cells: Role of L-<strong>Glutamat</strong>e and Pyruvate. Journal of Steroid Biochem. 36 (5): 473-8.<br />
Pike, R.N., D. Bagarozzi Jr and J. Travis. 1997. Immunological cross-reactivity of the Major<br />
Allergen from Perennial Ryegrass (Lolium Perenne), L01 pI, and the Cysteine Proteinase,<br />
Bromelain. Int. Arch. Allergy Immunol. 1123: 412-414.<br />
Pol, A. et al (1990). <strong>Glutamat</strong>e, the Dominant Excitatory Transmitter in Neuroendocrine<br />
Regulation. Sci 250: 1276-1278<br />
Portais, J. C. et al. 1991. Magnetic Resonance Spectroscopy and Metabolism. Applications<br />
of Proton and 13C NMR to the Study of <strong>Glutamat</strong>e Metabolism in Cultured Glial Cells and<br />
Human Brain In Vivo. Biochimie 73 (1): 93-7.<br />
www.giftig.me Seite 12
Privat, Alain et al. 1990. Neuronal Protection by Phenycyclidines: In Vitro<br />
Studies. Actual. Chim. Ther. 17: 187-200.<br />
Pulvirenti, Luigi. 1998. <strong>Glutamat</strong>e During the Natural History of Psychostimulant<br />
Dependence: Synaptic Plasticity and Medications Development. Speaker, NIDA meeting,<br />
The <strong>Glutamat</strong>e Cascade. University of Rome – Tor Vergata, Italy.<br />
Rao, G. S. and K. P. Pandya. 1989. Release of 2-Thiobarbituric Acid Reactive Products From<br />
<strong>Glutamat</strong>e or Deoxyribonucleic Acid by 1, 2, 4-Benzenetriol or Hrdroquinone in the<br />
Presence of Copper Ions. Toxicology 59 (1): 59-65.<br />
Rawls, S.M., McGinty, J.F., 1998. Presynaptic Kappa Opioid and Muscarinic Receptors<br />
Inhibit the Calcium-dependent Component of Evoked <strong>Glutamat</strong>e Release from Striatal<br />
Synaptosomes. J Neurochem. 73: 1058-1065.<br />
Rawls, S.M., McGinty, J.F. 1998. Kappa Receptor Activation Attenuates L-trans-PDC-evoked<br />
<strong>Glutamat</strong>e Levels in the Striatum. J Neurochem 70: 626-634.<br />
Rigdon, G. C. et al. 1989. Effect of Perinatal Monosodium <strong>Glutamat</strong>e Administration on<br />
Visual Evoked Potentials of Juvenile and Adult Rats. Neuro-Toxicology and Teratology 11<br />
(2): 121-128.<br />
Roberts, H.J. 1988. Reactions Attributed to Aspartame-containing Products: 551 Cases. J<br />
App Nutr 40: 85-94.<br />
Roberts, H.J. 1995. Aspartame and Headache. Neurology 45: 1631-1633.<br />
Roberts, H.J. 1988. Aspartame (NutraSweet®)-associated Epilepsy. Clin Res 36: 349A.<br />
Roberts, H.J. 1988 Complications Associated with Aspartame (NutraSweet®) in<br />
Diabetes. Clin Res 3: 489A.<br />
Roberts, H.J. 1991. Joint Pain Associated with Aspartame Use. Townsend letter for<br />
Doctors. May: 375-376.<br />
Roberts, H.J., 1993 Aspartame-associated Dry Mouth (Xerostomia). Townsend letter for<br />
Doctors. February: 201-202.<br />
Rochelle, Lori G. et al. 1990. Chlordecone Impairs Sodium-Stimulated l-(3h) <strong>Glutamat</strong>e<br />
Transport and Mobility of 16-Doxyl Stearate in Rat Liver Plasma Vesicles. Toxicol. Appl.<br />
Pharacol. 105 (2): 234-42.<br />
Rogawski, Michael E. 1998. <strong>Glutamat</strong>e Neurotransmission in Epilepsy: New Treatment<br />
Strategies. Speaker, NIDA meeting, The <strong>Glutamat</strong>e Cascade. National Institute of<br />
Neurological Disorders and stroke, National Institutes of Health.<br />
www.giftig.me Seite 13
Rosenberg, P.A., and E. Aizenman. 1989. Hundred-fold Increase in Neuronal Vulnerability to<br />
<strong>Glutamat</strong>e Toxicity in Astrocyte-Poor Cultures of Rat Cerebral Cortex. Neuroscience<br />
Letters 103 (2): 162-168. 116 (3) 399.<br />
Rothstein, J.D. et al. 1992. Decreased <strong>Glutamat</strong>e Transport by the Brain and Spinal Cord in<br />
Amyotropic Lateral Sclerosis. New England Journal of Medicine 326:1464-1468.<br />
Ruijter, J. M. and R. E. Baker. 1990. The Effects of Potassium-Induced Depolarization,<br />
<strong>Glutamat</strong>e Receptor Antagonists and N-Methyl-D-Aspartate on Neuronal Survival in<br />
Cultured Neocortex Explants. Int. J. Dev. Neurosci. 8 (4): 361-70.<br />
Sanico, Alvin, et al. 2000. Researchers Present New Theory for Allergic Diseases. American<br />
Journal of Respiratory and Critical Care Medicine.<br />
Schweitzer, L. et al. 1991. <strong>Glutamat</strong>e Neurotoxicity in Rat Auditory System Cochlear<br />
Nuclear Complex. Neurotoxicology Teratol 13 (2): 189-194.<br />
Shapiro, B. H. et al. 1993. Irreversible Suppression of Growth Hormone-Dependent<br />
Cytochrome P450 2C11 in Adult Rats Neonatally Treated with Monosodium<br />
<strong>Glutamat</strong>e. Journal of Pharmacology and Experimental Therapeutics 265(2):979-84.<br />
Shinora, S. et al. 1991. Inhibitory Effect of CCK-8 and Ceruletide on Neuronal Cell Death<br />
Induced by <strong>Glutamat</strong>e and its Possible Mechanism. 64th Annual Meeting of the Japanese<br />
Pharmacological Society 55 (Suppl. 1): 303.<br />
Siegal, T. et al. 1990. Experimental Neoplastic Spinal Cord Compression: Effect of Anti-<br />
Inflammatory Agents and <strong>Glutamat</strong>e Receptor Antagonists on Vascular<br />
Permeability. Neurosurgery 26 (6): 967-70.<br />
Simantov, R. 1989. <strong>Glutamat</strong>e Neurotoxicity in Culture Depends on the Presence of<br />
Glutamine: Implications for the Role of Glial Cells in Normal and Pathological Brain<br />
Development. Journal of Neurochemistry 52 (6): 1694-9.<br />
Singh, J. et al. 1990. Effect of Aspartate and <strong>Glutamat</strong>e on Carbon Tetrachloride Induced<br />
Liver Damage in Rats. Indian Journal of Experimental Biology 28 (12): 1180-3.<br />
Smith, J.D. et al. 2001. Relief of Fibromyalgia Symptoms Following Discontinuation of<br />
Dietary Excitotoxins. Annals of Pharmacotherapy 35(6):702-6.<br />
Solimena, M et al. 1990. Auto-antibodies to GABA-ergic Neurons and Pancreatic Cells in<br />
Stiff-man Syndrome. New England Journal of Medicine 322:1555-1560.<br />
Sorg, O. et al. 1997. Inhibition of Astrocyte <strong>Glutamat</strong>e Uptake by Reactive Oxygen Species:<br />
Role of Antioxidant Enzymes. Mol. Med 7: 431-440.<br />
Sucher, N.J. et al. 1991. Calcium Channel Antagonists Attenuate NMDA Receptor-Mediated<br />
Neurotoxicity of Retinal Ganglion Cells in Culture. Brain Research 551 (1-2): 297-302.<br />
www.giftig.me Seite 14
Summers, M.J. 1995. Administration of <strong>Glutamat</strong>e Following a Reminder Induces Transient<br />
Memory Loss in Day-old Chicks. Brain Research 3(1):1-8.<br />
Tamura, Y. et al. 1991. Ifenprodil-Induced Protection Against <strong>Glutamat</strong>e Cytotoxicity in<br />
Primary Culture of Cortical Neurons. 64th Annual Meeting of the Japanese Pharmacological<br />
Society 55 (Suppl. 1): 297.<br />
Tang-Christensen, M. et al. 1998. Glucagon-like Peptide 1 7-36 amide's Central Inhibition of<br />
Feeding and Peripheral Inhibition of Drinking Are Abolished by Neonatal Monosodium<br />
<strong>Glutamat</strong>e Treatment. Diabetes 47(4):530-7<br />
Tarkowski, S. 1974. Activity of <strong>Glutamat</strong>e Decarboxylase in the Brain of Rats Exposed to<br />
Carbon Disulfide. International Archiv Fuer Arbeitsmedizin 33 (1) 79-82.<br />
Teal, G.E. et al. 1998. Increased <strong>Glutamat</strong>ergic Neurotransmission and Oxidative Stress<br />
After Alcohol Withdrawal. Am J Psychiat 155: 726-732.<br />
Terrian, David, M. et al. 1991. Domoic Acid Enhances the Potassium-Evoked Release of<br />
Endogenous <strong>Glutamat</strong>e From Guinea Pig Hippocampal Mossy Fiber Synaptosomes. Brain<br />
Research 551 (1-2): 303-7.<br />
Tomita, M et al. 1990. Ionic Concentration of Shifting Fluid During <strong>Glutamat</strong>e-Induced<br />
Swelling of Cultured Glioma Cells Estimated by the Cytocrit Technique. Adv. Neurology 52:<br />
558.<br />
Tzimagiorgis, G. et al. 1991. Chromosomal Mapping of <strong>Glutamat</strong>e Dehydrogenase Gene<br />
Sequences to Mouse Chromosomes 7 and 14. Genomics 10 (1) 83-8.<br />
Villalobos, Carlos et al. 1996. Functional <strong>Glutamat</strong>e Receptors in a Subpopulation of<br />
Anterior Pituitary Cells. FASEB J. 10: 654-660.<br />
Vornov, J. J. and J. T. Coyle. 1991. <strong>Glutamat</strong>e Neurotoxicity and the Inhibition of Protein<br />
Synthesis in the Hippocampal Slice. Journal of Neurochemistry 56 (3): 996-1006.<br />
Walling, Anne D. Predicting Which Strokes Will Progress: <strong>Glutamat</strong>e Levels. 1997. American<br />
Family Physician: 55(7): 2532(1).<br />
Wang, J.Q., McGinty, J.F. 1999. <strong>Glutamat</strong>e-dopamine Interactions Mediate the Effects of<br />
Psychostimulant Drugs. Addiction Biology. 4: 143-152.<br />
Weeing-Verhoeff, E. J. D. et al. 1990. Involvement of Aspartic and Glutamic Residues in<br />
Kringle-2 of Tissue-Type Plasminogen activator in Lysine Binding, Fibrin Binding and<br />
Stimulation of Activity as Revealed by Chemical Modification and Oligonucleotide-Directed<br />
Mutagenesis. Protein Engineering 4 (2) 191-8.<br />
Whetsell, W. and Shapira, N. 1993. Biology of Disease. Neuroexcitation, Excitotoxicity and<br />
Human Neurological Disease. Lab Invest 68: 372-387.<br />
www.giftig.me Seite 15
Wolf, Marina E. 1998. <strong>Glutamat</strong>e-Mediated Neuroplasticity: Role in Amphetamine<br />
Addiction. Speaker, NIDA meeting, The <strong>Glutamat</strong>e Cascade. The Chicago Medical School.<br />
Wong, C. C. et al. 1988. Effect of Neonatal Monosodium-L-<strong>Glutamat</strong>e Treatment on the<br />
Response of Isolated Uterine Preparation To Various Uterine Contraction Stimulators. Gen.<br />
Pharmacol.19 (5): 673-677.<br />
Wong, P.T. et al. 1997. Deficits in Water Escape Performance and Alterations in<br />
Hippocampal Cholinergic Mechanisms Associated with Neonatal Monosodium <strong>Glutamat</strong>e<br />
Treatment in Mice.Pharmacology, Biochemistry and Behaviour 57(1-2):383-8.<br />
Xu, C. J. et al. 1997. Effect of Phosphomonoesters, Phosphodiesters, and PhosphoCreatine<br />
on <strong>Glutamat</strong>e Uptake by Synaptic Vesicles. Molecular and Chemical Neuropathology 32(1-<br />
3):89-99.<br />
Yamamoto, T, et al. 1993. Plasma Levels of Insulin-like Growth Factor-I are Reduced at one<br />
Week of Age in Monosodium L-<strong>Glutamat</strong>e-Treated Mice. Endocrine Journal 40(4):461-5.<br />
Yanai, A. et al. 1991. 4-0 Methylpyridoxine-Induced Convulsion Accompanied by a<br />
Decreased Cerebral GABA Level in Guinea Pigs. 64th Annual Meeting of the Japanese<br />
Pharmacological Society55 (Suppl. 1): 303.<br />
Yokota, I. et al. 1990. Molecular Basis of Medium Chain Acyl-Coenzyme A Dehydrogenase<br />
Deficiency. An A to G Transition at Position 985 That Causes a Lysine-304 to <strong>Glutamat</strong>e<br />
Substitution in the Mature Protein is the Single Prevalent Mutation. J. Clinical Invest. 86 (3):<br />
1000-1003.<br />
Yu, T. et al. 1997. Effects of Maternal Oral Administration of Monosodium <strong>Glutamat</strong>e at a<br />
Late Stage of Pregnancy on Developing Mouse Fetal Brain. Brain Research 747(2):195-206.<br />
Zeevalk, G. D. and W. J. Nicklas. 1990. Chemically Induced Hypoglycemia and Anoxia:<br />
Relationship To <strong>Glutamat</strong>e Receptor-Mediated Toxicity in Retina. J. Pharmacology and<br />
Experimental Therapy 253 (3): 1285-1292.<br />
Zharikov, S. I. et al. 1990. Effect of Alpha-Latrotoxin on the Processes of <strong>Glutamat</strong>e Uptake<br />
and Release in Rat Brain Synaptosomes. Biol. Membr. 7(10): 101321<br />
Zhao, X. N. et al. 1990. Morphine Enhancement of <strong>Glutamat</strong>e and Kainic Acid<br />
Neurotoxicity. Met. Ions Biol. Med. Proc. Int. Symp. pp 156-8.<br />
Zieglgansberger, Walter and Planck, M. 1998. Acamprosate, a Novel Anti-craving<br />
Compound Acts Via <strong>Glutamat</strong>ergic Pathways. Speaker, NIDA meeting, The <strong>Glutamat</strong>e<br />
Cascade. Institute of Psychiatry, Munich, Germany.<br />
Zukin, Stephen R. 1998. Schizophrenia: A <strong>Glutamat</strong>ergic Perspective. Speaker, NIDA<br />
meeting, The <strong>Glutamat</strong>e Cascade. National Institute on Drug Abuse, National Institutes of<br />
Health.<br />
www.giftig.me Seite 16
www.giftig.me Seite 17