Leber und einige Modelle

Literatur• Löffler/Petrides, Biochemie und Pathobiochemie,Springer Verlag, 2002• Moll/Moll, Anatomie,Gustav-Fischer-Verlag, 1997• B. A. Saville, M. R. Gray and Y. K. Tam, Models of hepatic drug elimination,Drug Metabolism Reviews, 24(1), 49-88, 1992.• K. S. Pang and M. Rowland, Hepatic clearance of drugs. I. Theoreticalconsiderations of a „well-stirred“ model and a „parallel tube“ model.Influence of hepatic blood flow, plasma and blood cell binding, and thehepatocellular enzymatic activity on hepatic drug clearance, Journal ofPharmacokinetics and Biopharmaceutics, Vol.5, No. 6, 1977.• M. R. Gray and Y. K. Tam, The series-compartment model for hepaticelimination, Drug Metabolism and Disposition, Vol. 15, 22-27, 1987.