Decreased Circulating Level of Soluble Glycoprotein ... - EuroJournals
Decreased Circulating Level of Soluble Glycoprotein ... - EuroJournals
Decreased Circulating Level of Soluble Glycoprotein ... - EuroJournals
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<strong>Decreased</strong> <strong>Circulating</strong> <strong>Level</strong> <strong>of</strong> <strong>Soluble</strong> <strong>Glycoprotein</strong>-130 in Recurrent Miscarriage Patients 70<br />
Thus, all these evidences could confirm which lower sgp130 in patients may be a probable<br />
consequence <strong>of</strong> their higher depression.<br />
5. Summary and Concluding Remarks<br />
Taken together, indeed, as a new result, we found that the changes <strong>of</strong> some blood parameters like the<br />
lower post-abortion level <strong>of</strong> sgp130 or higher level <strong>of</strong> some autoimmune markers along with a higher<br />
depression score may be associated with recurrent spontaneous abortion. To our knowledge, this study<br />
is also relatively novel in that it simultaneously examines the relationship between serum sgp130 levels<br />
in recurrent miscarriage patients and their autoantibody titers, some coagulation parameters, the level<br />
<strong>of</strong> Hcy, GCT, FBS, CRP and RF as well as the socio-demographic, psychological, environmental,<br />
dietary, laboratory, smoking and lifestyle parameters all <strong>of</strong> which were intelligently defined as<br />
quantitative values.<br />
Further studies are needed to determine whether the discussed changes in our parameters are a<br />
cause <strong>of</strong>, or merely a consequence <strong>of</strong> their abortion event or even abortion-related depression. Further<br />
studies are also required to justify the role <strong>of</strong> sgp130 in recurrent miscarriage.<br />
Thus we can summarize by saying that psychological problems, inflammation and autoimmune<br />
processes may be associated with each other and with recurrent abortion.<br />
Hopefully, these additional information and knowledge provided will, before long, lead to more<br />
successful treatment and improved outcome in miscarriage women.<br />
Acknowledgments<br />
The authors would like to thank Islamic Azad University, Kazerun Branch for their financial and other<br />
support as well as Dr. Parvin Javad Baghdasar (from Molavi clinical Laboratory, Shiraz, Iran), for her<br />
assistance with data collection and patient referrals.<br />
Conflict <strong>of</strong> interest: None declared.<br />
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