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10:45 –<br />

11:10<br />

11:15 –<br />

12:45<br />

Keynote<br />

11:15<br />

2B.1<br />

11:31<br />

2B.2<br />

11:39<br />

2B.3<br />

11:47<br />

2B.4<br />

11:55<br />

2B.5<br />

12:03<br />

2B.6<br />

12:11<br />

2B.7<br />

12:19<br />

2B.8<br />

12:27<br />

Large Auditorium<br />

Thursday September 27<br />

Presidential Guest Lecture<br />

Translational Research between dentistry & orthopaedics<br />

Jenneke Klein Nulend, ACTA, VU University & University of <strong>Amsterdam</strong>, Netherlands<br />

Lecture Room SESSION 2B: Cells & Molecular 1<br />

Bone cell mechanosensing: On shapes and forces<br />

Rommel Bacabac<br />

San Carlos University, Cebu, Philippines<br />

BMP-­‐2 and BMP-­‐7: Differential Regulation of Chondrogenic Differentiation<br />

Page 17<br />

Chairs: Harrie Weinans<br />

Agata Nyga<br />

Marjolein Caron*, Pieter Emans, Marielle Coolsen, Don Surtel, Andy Cremers, Lodwijk van Rhijn, Tim Welting<br />

*Maastricht University Medical Center, Dept. Orthopaedic Surgery, Maastricht, Netherlands<br />

Macrophages response to wear particles is determined by macrophage polarization<br />

Jukka Pajarinen*, Vesa-­‐Petteri Kouri, Jami Mandelin, Jari Salo, Yrjö Konttinen<br />

*Department of Medicine, Institute of Clinical Medicine, University of Helsinki, Helsinki, Finland<br />

Inhibition of NF-­‐kB activation delays the onset of age-­‐dependent spinal degeneration in a murine model of human<br />

progeria<br />

Luigi Aurelio Nasto*, Enrico Pola, Andria Robinson, Arvydas Usas, Gwendolyn Sowa, Paul Robbins, Laura Niedernhofer,<br />

James Kang, Nam Vo<br />

*Department of Orthopaedic Surgery, Catholic University of Rome, Rome, Italy<br />

Innate immune sensors enhanced macrophagic reaction after phagocytosis of wear debris in so-­‐called “aseptic ”<br />

condition<br />

Yasushi Naganuma*, Tomoyuki Hirayama, Yasunobu Tamaki, Yuya Takakubo, Kan Sasaki, Michiaki Takagi<br />

*Yamagata University, Yamagata, Japan<br />

Modulation of osteoclast formation by cyclically-­‐strained myotubes is mediated by IL-­‐6<br />

Petra Juffer*, Richard Jaspers, Jenneke Klein-­‐Nulend, Astrid Bakker<br />

*Department of Oral Cell Biology, Academic Centre for Dentistry <strong>Amsterdam</strong> (ACTA), University of <strong>Amsterdam</strong> and VU University<br />

<strong>Amsterdam</strong>, MOVE Research Institute <strong>Amsterdam</strong>, Netherlands<br />

Eicosapentanoic acid prolongs survival and attenuates inflammatory response in an experimental model of lethal trauma<br />

Stephanos Koutsostathis*, Christos Paganias, Thomas Tsaganos, Nikitas Schizas, Evangelos Giamarellos-­‐ Bourboulis,<br />

Eleftheria Kontou, George Macheras<br />

*KAT Hospital, Kifissia, Athens, Greece<br />

Elevated Lysyl hydroxylase 2b expression during experimental OA; the potential cause of persistent synovial fibrosis<br />

Dennis Remst*, Esmeralda Blaney Davidson, Elly Vitters, Arjen Blom, Reinout Stoop, Jessica Snabel, Ruud Bank, Wim van<br />

den Berg, Peter van der Kraan<br />

*Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands<br />

Deleterious interaction between BMP2 and TGF-­‐beta signaling in articular chondrocytes: Harmful role for BMP2 in OA?<br />

Esmeralda Blaney Davidson*, Arjan van Caam, Laurie de Kroon, Elly Vitters, Wim van den Berg, Peter van der Kraan<br />

* Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands<br />

2B.9 The bio-­‐mechano-­‐reactor: design and development of a new tool for Osteoarthritis research<br />

12:35–<br />

12:43 Thijs de Jong*, Karen Wiegant, Simon Mastbergen, Floris Lafeber<br />

*University Medical Center Utrecht, Utrecht, Netherlands<br />

12:45 –<br />

14:00<br />

Lunch & Poster Session 1<br />

13:00 –<br />

13:50<br />

Meet-­‐a-­‐Mentor Session<br />

Young Investigators + Experienced Seniors

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