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14:00 –<br />

15:30<br />

3B.1<br />

14:00<br />

3B.2<br />

14:08<br />

3B.3<br />

14:16<br />

3B.4<br />

14:24<br />

3B.5<br />

14:32<br />

3B.6<br />

14:40<br />

3B.7<br />

14:48<br />

Lecture Room SESSION 3B: Cells & Molecular 2<br />

Thursday September 27<br />

Page 19<br />

Chairs: Sjoerd Bulstra<br />

Francesca Perut<br />

Mechanical stimulation of tendon-­‐derived cells and investigation of its influence on gene expression<br />

Kreja Ludwika*, Anita Ignatius, Matthias Schieker, Denitsa Docheva<br />

*Institute of Orthopaedic Research and Biomechanics, University of Ulm, Ulm, Germany<br />

Human End-­‐Stage Osteoarthritic Cartilage is Responsive to Transforming Growth Factor Beta and Contains a Population<br />

of Cells that Expresses SMAD2/3P and SMAD1/5/8P<br />

Arjan van Caam*, Esmeralda Blaney Davidson, Elly Vitters, Wim van den Berg, Peter van der Kraan<br />

*Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands<br />

Heat Shock proteins 70 and 90 in osteoarthritis progression<br />

Michiel Siebelt*, Harald Groen, Marjan Sandker, Erwin Waarsing, Nicole Kops, Christina Muller, Jan Verhaar, Marion de<br />

Jong, Willem van Eden, Holger Jahr, Harrie Weinans<br />

*Dept. of Orthopaedic Surgery, Erasmus Medical Center, Rotterdam, Netherlands<br />

Fluid flow induced osteoclast differentiation is associated with alterations in genes regulating IL-­‐6 signaling, cell death<br />

and osteoblast differentiation<br />

Anna Fahlgren*, Rune Madsen, Aleksey Dvorzhinskiy, Benjamin McArthur, Göran Andersson, Patrick Ross, Mathias Bostrom<br />

*Hospital for Special Surgery, New York, USA<br />

Utilization of platelet rich plasma (PRP) in orthopeadic practice: clinical and biological analysis of terapeutic effectivenes<br />

Rocco Papalia*, Francesco Franceschi, Gianluca Vadalà, Biagio Zampogna, Sebastiano Vasta, Lorenzo Diaz Balzani, Andrea<br />

Tecame, Erika Albo, Nicola Maffulli, Vincenzo Denaro<br />

*Campus Bio Medico University Hospital -­‐ Department of Orthopaedic and Trauma Surgery, Rome, Italy<br />

Isoprostane levels are altered in rheumatoid arthritis and suppress NF&#954;B activity to inhibit osteoclast formation<br />

Seint Lwin*, Joshua Brooks, Lynett Danks, Karen Lundberg, Jason Morrow, Ginger Milne, James Edwards<br />

*University of Oxford, UK<br />

Synovial Wnt and WISP1 expression leads to OA-­‐like cartilage damage by skewing of TGF-­‐beta signaling<br />

Martijn van den Bosch*, Arjen Blom, Peter van Lent, Henk van Beuningen, Fons van de Loo, Esmeralda Blaney Davidson,<br />

Peter van der Kraan, Wim van den Berg<br />

*Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands<br />

3B.8 Differences in expression profiles of osteolysis-­‐related cytokines in tissues retrieved from aseptically failed hip and knee<br />

arthroplasties<br />

3B.9<br />

14:56<br />

3B.10<br />

14:04<br />

Tereza Tomankova*, Eva Kriegova, Martin Petrek, Jiri Gallo<br />

*Laboratory of Immunogenomics and Immunoproteomics, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech<br />

Republic<br />

Continued cell exposure to parathyroid hormone-­‐related peptide (1-­‐36) decreases osteogenic and angiogenic gene<br />

expression<br />

Timothy Hardwick*, Priya Kalia, Joanna Baawa-­‐Ameyaw, Daniel Lozano, Joydeep Sinha, Lucy Di Silvo<br />

*King's College Health Partnerships, London, UK<br />

The BMP2-­‐eNOS Axis Regulates Bone Development and Anabolic Effects of Statins<br />

Megan Weivoda*, Ross Garrett, Jonathon Lowrey, Gloria Gutierrez, Gregory Mundy, James Edwards<br />

*University of Oxford, UK<br />

3B.11 Nfat5 is involved in in vitro chondrogenic differentiation under normal and increased tonicity<br />

14:12 –<br />

14:20 Marjolein Caron*, Anna van der Windt, Pieter Emans, Lodwijk van Rhijn, Holger Jahr, Tim Welting<br />

*Maastricht University Medical Center, Dept. Orthopaedic Surgery, Maastricht, Netherlands<br />

15:30 –<br />

15:50<br />

Coffee break

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