CURRICULUM VITAE Personal details Name: Bruno Markus ...

Personal details 

PD Dr. med. Bruno M. Balsiger | Facharzt FMH für Gastroenterologie 

Name: Bruno Markus Balsiger 

CURRICULUM VITAE 

Business Address: Hochhaus Lindenhofspital 

Bremgartenstrasse 119 

CH-3001 Bern 

Phone +41 31 302 32 34 

Fax +41 31 302 32 35 

E-Mail: bruno.balsiger@hin.ch 

balsiger.bruno@smile.ch 

Private Address: Jetzikofenstrasse 16, CH-3038 Kirchlindach, Switzerland 

Date of birth: 5/3/1963 

Citizen of: Switzerland 

Marital status: Married with Dorothea Anna Kuratle 

Children: 4; 

Lukas Michaja 9/16/1991, 

Annina Lena 9/20/1993, 

Laura Tabea 6/28/1995, 

Kayla Rebecca 6/5/1998 

Languages: German (Native language), English and French 

Army: Special officer in the rank of a captain in the psychological support 

service. 

1

School education 


All schools absolved in Berne (4 years Primary School, 4 years Secondary School, 4 

1/2 Years Grammar School with finals in 1982) 

Studies 

Studies of medicine at the Medical Faculty of the University of Berne 1983-1990 

Final exams in 1989 and 1990 

Promotion 

Promotion as Dr. med. July 26 1993, Prof. Dr. med. U. Boschung, Institute of medical 

History, Universitiy of Berne 

Venia Docendi 

Habiltiation in experimental Gastroenterology, venia docendi University of Bern, Nov. 

2005 

Work as a medical doctor 

Medical resident in the section for autopsy at the Institute of Pathology of the University 

of Berne Jan 1- Dez 31 1991 (Prof. J. Laissue, Prof. T. Schaffner) 

Resident in the Hospital of Wattenwil Surgery/ Gynecology/ Internal Medicine from 

June 12 1992- June 30 1994 (Dr. B. Roth, Dr. R. Barandun, Dr. N. von Rechenberg) 

Resident at the University of Berne, Department of Visceral and Transplantation Surgery 

July 1 1994- April 30 1996 (Chairman: Prof. M.W. Büchler) 

Research Fellow at the Gastroenterology Research Unit, Mayo Clinic, Rochester, Minnesota, 

USA, May 1, 1996 – June 30, 1999 (Prof. M.G. Sarr) 

University of Berne, Department of Visceral and Transplantation Surgery, July 1 1999 

- February 29 2000 (Chairman: Prof. M.W. Büchler) 

Research Fellow at the Gastroenterology Research Unit, Mayo Clinic, Rochester, Minnesota, 

USA, March 1 – May 31 2000 (Prof. M.G. Sarr) 

Resident at the University of Berne, Department of Visceral and Transplantation Surgery, 

June 1 2000 - September 30 2000 (Chairman: Prof. M.W. Büchler) 

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Senior resident at the University of Berne, Department of Visceral and Transplantation 

Surgery, Oct 1 2000 - Dec 31 2000 (Chairman: Prof. M.W. Büchler) 

Consultant (Oberarzt) at the University of Berne, Department of Visceral and Transplantation 

Surgery Jan 1 2001- April 30 2001 (Chairman: Prof. M.W. Büchler) 

Consultant (Oberarzt) Dept. of Surgery Hospital Center of Biel (clinical work) and 

at the University of Berne, Department of Visceral and Transplantation Surgery (research) 

May 1 2001- Nov 30 2002 (Chairmen: Prof. M.W. Büchler/Prof. D. Candinas, 

Bern and Prof.U.Laffer, Biel) 

Responsible for obesity surgery patient program, including preoperative and postoperative 

care and follow up 1994 -1996 and 1999 -2001 

Collaboration in outpatient program for Patients with inflammatory bowel disease. Jan 

1- Dec 31 2000 

Within the scope of a Swiss Government academic support position (“Bundesförderungsstelle”), 

Oct 1. 2000 till Sept 30 2004 and regular position since October first 

2004 

Consultant (Oberarzt) for outpatient obesity program University of Berne Endocrinology 

Unit Aug 1, 2003 – June 30, 2004 (Chairman: PD P. Diem) 

Resident at the University of Berne, Gastroenterology Unit, Dec 1 2002 – Dec 31 2005 

(Chairman: Prof. H.U. Scheurer) 

. 

Resident at the University of Basel, Gastroenterology Unit, Jan 1 – Dec 31 2006 

(Chairman: Prof. C. Beglinger) 

Junior Consultant (stv. Oberarzt) Spitalbern Tiefenau Medizin Jan 1 2007 – April 30 

2008 (Prof. H.R. Baur) 

Additional training 

Certificate of AO course in basic treatment of fractures, Davos 2001 

Certificate of Gastrointestinal Surgery course of the international society for gastrointestinal 

surgery, Davos 2002 

Certification for Advanced Trauma and Live Support (ATLS), Zurich 2002 

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Specially selected abstracts 


Society for Surgery of the Alimentary Tract, Annual meeting May 17 - 20, 1998, New 

Orleans, USA 

SSAT and Ross Resident’s conference May 16th 1998, invitation and nomination (one 

of the best twenty abstracts) for the abstract: 

Small bowel transplantation (SBT) alters non-adrenergic non-cholinergic (NANC) inhibition 

in longitudinal smooth muscle of the rat jejunum. 

European Society for Surgical Research, 34th congress, April 22-24, 1999, Bern, Switzerland 

Nomination for Walter Brendel Session (second highest scoring abstract out of 500) 

with the abstract : 

Chronic lack of extrinsic neural input increases nitric oxide (NO) independent inhibition 

after rat small bowel transplantation (SBT). 

Society for Surgery of the Alimentary Tract, Annual meeting May 16 - 19, 1999, Orlando, 

USA 

SSAT and Ross Resident’s conference May 15th 1998, invitation and nomination (one 

of the best twenty abstracts) for the abstract: 

Roux-en-Y gastric bypass as a remedial operation for gastroesophageal reflux (GER) 

after vertical banded gastroplasty (VBG) 

Day of clinical research, University of Bern, Nov 13, 2002, Bern, Switzerland: third highest 

scoring of work performed by medical students (Seiler R) Muscular and neuronal 

adrenergic receptor mechanisms in rat ileal longitudinal muscle contractility. 

Society for Surgery of the Alimentary Tract, Annual meeting May 18 - 21, 2003, Orlando, 

USA 

SSAT residents and fellows research conference May 17th 2003, invitation and nomination 

(one of the best twenty abstracts) for the abstract: 

Acute pancreatitis induces ileus by upregulating TNF and Nitric Oxide in the small 

intestine. 

Grants and scholarships 

1996-97 Department of Visceral and Transplantation Surgery, University of Bern: 

support for : The effects of small bowel autotransplantation on jejunal and ileal circular 

smooth muscle function in vitro in dogs. 

1997 Astra Pharmaceuticals, Switzerland: support for: The effects of small bowel 

autotransplantation on jejunal and ileal circular smooth muscle function in vitro in dogs. 

1997 Novartis Nutrition: support for: The effects of small bowel autotransplantation 

on jejunal and ileal circular smooth muscle function in vitro in dogs. 

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1997-98 Swiss National Science Foundation: fellowship for prospective researchers 

for the project: The role of nitric oxide in rat jejunal and ileal longitudinal smooth muscle 

before and after small bowel transplantation. 

1998 Novartis Foundation: support for: The effects of small bowel autotransplantation 

on jejunal and ileal circular smooth muscle function in vitro in dogs. 

1998 Swiss Society for Gastroenterology and Hepatology: support in addition 

for: The role of nitric oxide in rat jejunal and ileal longitudinal smooth muscle before 

and after small bowel transplantation. 

1998-99 Swiss Foundation for medical and biological science: fellowship for advanced 

researchers for a project extension (results one year after transplantation): The 

role of nitric oxide in rat jejunal and ileal longitudinal smooth muscle before and after 

small bowel transplantation. 

1998 Special Credit University of Bern: High Tech 5ml, 12 channel organchamber 

system including electro stimulation and computer hard and software. 

1999 Department of Clinical Research, University of Bern: Grant in aid for: Neuromuscular 

transmission and control of smooth muscle activity in the human intestine. 

2000 Special Credit University of Bern: Eight additional high Tech 10ml organchambers 

2001 (August) – 2003 (July) Swiss National Science Foundation project grant: (Nr. 

3100-061583) : Small bowel transplantation: changes in receptor specific adrenergic 

neuromuscular mechanisms in the rat ileum 

2000 (Oct 1) – 2004 (Sept 30) Swiss Government academic support position 

(“Bundesförderungsstelle”) 

2003 (August 1) – 2004 (Sept 30) Special extension of Swiss National Science 

Foundation project grant: (Nr. 3100-061583) : Small bowel transplantation: changes 

in receptor specific adrenergic neuromuscular mechanisms in the rat ileum 

Active Collaboration 

Prof. Jukka Takala, Chair: Intensiv Care Unit, University of Bern, Inselspital, Bern 

Effect of endotoxin on contractile properties of splanchnic vasculature and small bowel 

in pigs. 

Dr. Sidney Shaw, Departement of clinical research, University of Bern 

Prof. U. Honegger, Departement of Pharmacology, University of Bern 

Michel Murr, MD, associate Professor of Surgery, University of South Florida, Tampa, 

FL, USA 

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Michael Sarr, MD, Professor of Surgery and Chair General and Gastrointestinal Surgery, 

Mayo Clinic, Rochester, MN, USA 

PD J. Gschossmann, Departement of Gastroenterology, University of Bern 

Prof. Ch. Beglinger, Departement of Gastroenterology, University of Basel 

Memberships 

a.o. Mitglied der Schweizerischen Aerztegesellschaft 

Verein Schweizerischer Assistenz und Oberärzte 

European Digestive Surgery 

Swiss study group for morbid Obesity 

International Federation for the Surgery of Obesity 

Deutsche Gesellschaft fuer Adipositasforschung 

The Society for Surgery of the Alimentary Tract 

Advanced Trauma and Life Support (ATLS) 

Publications 

Original articles in peer reviewed journals 

1.) Seiler CA, Balsiger BM, Feodorovici M, Baer HU, Büchler MW. Extensive intraoperative 

lavage: the key maneuver in the treatment of severe peritonitis. Dig Surg 

1996;13:400-404 (IMPF 0.645; R 95/139) 

2.) Shibata C, Balsiger BM, Anding WJ, Sarr MG. Adrenergic denervation-hypersensitivity 

in ileal smooth muscle after small bowel transplantation in rats. Dig Dis Sci 

1997; 42: 2213-2221 (IMPF 1.438; R 27/45) 

3.) Shibata C, Murr MM, Balsiger BM, Anding WJ, Sarr MG. Contractile activity of 

smooth muscle in rats 1 year after small bowel transplantation: differing adaptive 

response of the jejunum and ileum to denervation. J Gastrointest Surg 1998; 

2:463-472 (IMPF 1.99; 28/141) 

4.) Shibata C, Balsiger BM, Anding WJ, Duenes JA, Miller VM, Sarr MG. Functional 

changes in non-adrenergic non-cholinergic inhibitory neurons in ileal circular 

smooth muscle after small bowel transplantation in rats. Dig Dis Sci 1998; 43: 

2446-2454 (IMPF 1.438 R 27/45) 

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5.) Luque-de Leon E, Tsiotos GG, Balsiger BM, Barnwell J, Burgart LJ, Sarr MG. 

Staging Laparascopy for pancreatic cancer should be used to select the best 

means of palliation and not only to maximize resectability rate. J Gastrointestinal 

Surg. 1999;3:111-118 (IMPF 1.99; 28/141) 

1.) Murr MM, Balsiger BM, Kennedy FP, Mai JL, Sarr MG. Malabsorptive Procedures 

for Severe Obesity: A Comparison of Pancreaticobiliary Bypass (PBB) and Very 

Very Long Limb Roux-en-Y Gastric Bypass (VVLGB). J Gastrointestinal Surg. 

1999;3:607-612 (IMPF 1.99; 28/141) 

2.) Brugger LE, Seiler CA, Mettler M, Balsiger BM, Feodorovici M, Baer HU, Buchler 

MW: [New approaches to the surgical treatment of diffuse peritonitis]. Zentralbl 

Chir 124:181-6, 1999 (IMPF 0.259; 128/141) 

3.) Murr MM, Balsiger BM, Farrugia G, Sarr MG. Role of nitric oxide, VIP and ATP in 

inhibitory neurotransmission in human jejunum. J Surg Res. 1999;84:8 –12 (IMPF 

1.726; 34/141) 

4.) Ohtani N, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Small bowel transplantation 

induces adrenergic denervation-hypersensitivity in ileal longitudinal smooth 

muscles in rats. J Gastrointest Surg 2000;4:77-85 (IMPF 1.99; 28/141) 

5.) Naef M, Sadowski C, de Marco D, Sabbioni M, Balsiger BM, Laederach K, Burgi 

U, Buchler MW: [Mason vertical gastroplasty in treatment of morbid obesity. 

Results of a prospective clinical study]. Chirurg 71:448-55, 2000 (IMPF 0.848; 

72/141) 

6.) Balsiger BM, Kennedy FP, Abu-Lebdeh HS, et al. Prospective evaluation of Rouxen-Y 

gastric bypass as primary operation for medically complicated obesity [see 

comments]. Mayo Clin Proc 2000; 75(7):673-80. (IMPF 2.868; 14/107) 

7.) Balsiger BM, Murr MM, Mai J, Sarr MG. Gastroesophageal reflux after intact vertical 

banded gastroplasty: correction by conversion to Roux-en-Y gastric bypass. J 

Gastrointest Surg 2000; 4(3):276-81. (IMPF 1.99; 28/141) 

8.) Balsiger BM, , Poggio JL, Mai J, Sarr MG. Ten and more years after Vertical 

banded gastroplasty as primary operation for morbid obesity. J Gastrointest Surg 

2000;4:598-605 (IMPF 1.99; 28/141) 

9.) Balsiger BM, Duenes JA, Ohtani N, Shibata C, Farrugia G, Anding WJ, Sarr MG. 

Nitric oxide pathways in circular muscle of the rat jejunum before and after small 

bowel transplantation. J Gastrointest Surg 2000;4:86-92 (IMPF 1.99; 28/141) 

10.) Balsiger BM, Ohtani N, Anding WJ, Duenes JA, Zinsmeister AR, Sarr MG: Chronic 

extrinsic denervation after small bowel transplantation in rat jejunum: effects 

and adaptation in nitrergic and non-nitrergic neuromuscular inhibitory mechanisms. 

Surgery 129:478-89. 2001(IMPF 2.631; R 12/141) 

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11.) Zyromski NJ, Duenes JA, Kendrick ML, Balsiger BM, Farrugia G, Sarr MG: Mechanism 

mediating nitric oxide induced inhibition in human jejunal longitudinal 

smooth muscle. Surgery 130:489-96. 2001 (IMPF 2.631; R 12/141) 

12.) Sabbioni ME, Dickson MH, Eychmüller S, Franke D, Goetz S, Hürny Ch, Naef M, 

Balsiger BM, de Marco Doris, Bürgi U, Büchler MW: Intermediate results of health 

related quality of life after vertical banded gastroplasty. Int J Obes Relat Metab 

Disord 26:277-80. 2002 (IMPF 2.363; 38/88) 

13.) Balsiger BM, Rickenbacher A, Biecker E, Tsui J, Dashwood M, Reichen J, Shaw 

S.G: Endotheline A-receptor blockade in experimental diabetes improves Glucose 

balance and gastrointestinal function. Clin Sci (Lond) 103 Suppl 1:430S-3S. 2002 

(IMPF 1.941; 28/74) 

14.) Balsiger BM, He CL, Zyromski NJ, Sarr MG: Neuronal adrenergic and muscular 

cholinergic contractiele hypersensitivity in canine jejunum after extrinsic denervation. 

J Gastrointest Surg. 2003 May-Jun;7(4):572-82 (IMPF 1.99; 28/141) 

15.) Balsiger BM, Sarr MG: Chronic extrinsic denervation of the small bowel: effect on 

adrenergic and cholinergic contractile mechanisms in canine ileal circular muscle. 

Surgery. 2003 Nov;134 (5):783-90. (IMPF 2.631; R 12/141) 

16.) Clark MM, Balsiger BM, Sletten CD, Litzinger KL, Wolff G, Williams DE, Abu-Lebdeh 

HS, Sarr MG: Psychologic factors as predictors of two-year outcome following 

bariatric surgery for weight loss. Obes Surg. 2003 Oct;13 (5):739-45. (IMPF 2.356; 

R20/141) 

17.) Seiler R, Rickenbacher A, Shaw SG, Balsiger BM: Role of α1, α2, β1, β2, and 

β3- Adrenergic Receptor Mechanisms in Spontaneous Contractile Activity of Rat 

Ileal Longitudinal Smooth Muscle. J Gastrointest Surg 2005; 9: 227-235 (IMPF 

1.99; 28/141) 

18.) Muller S, Arni S, Varga L, Balsiger BM, Hersberger M, Maly F, Seibold F. Serological 

and DNA-based evaluation of Chlamydia pneumoniae infection in inflammatory 

bowel disease. Eur J Gastroenterol Hepatol. 2006 Aug;18(8):889-94. (IMPF 

1.69; 29/46) 

19.) Rickenbacher A, Seiler R, Honegger U, Shaw SG, Balsiger BM: Role of β1-, β2-, 

and β3-Adrenoceptors in Contractile Hypersensitivity in a Model of Small Bowel 

Transplantation. Surgery 2008 

Original work, not peer reviewed 

1.) Balsiger BM, Ohtani N, Farrugia G, Sarr MG. Delayed induction of K+-channel 

dependent non-nitrergic inhibition in longitudinal smooth muscle of rat jejunum. 

Proceedings of the Falk Symposium 112; 231-235. 2000, Kluwer Academic Publishers, 

Dordrecht, NL 

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Review articles in peer reviewed journals 

1.) Balsiger BM, Luque-de Leon E, Sarr MG. Surgical treatment of obesity: who is an 

appropriate candidate? Mayo Clin Proc 1997; 72:551-558 (IMPF 2.868; R 14/107) 

2.) Balsiger BM, Murr MM, Poggio JL, Sarr MG. Bariatric surgery. Surgery for weight 

control in patients with morbid obesity. Med Clin North Am 2000; 84(2):477-89 

(IMPF 2.138; 20/107) 

3.) Sakorafas GH, Tsiotou AG, Balsiger BM: Axillary lymph node dissection in breast 

cancer: current status and controversies, alternative strategies, and future perspectives. 

Acta Oncol 2000;39(4):455-466 (IMPF 1.909; 60/114) 

4.) Sakorafas GH, Friess H, Balsiger BM, Büchler MW, Sarr MG. Problems of reconstruction 

during pancreatoduodenectomy. Dig Surg 18:363-9, 2001 (IMPF 

0.645; R 95/141) 

Review articles, not peer reviewed 

1.) Sarr MG, Balsiger BM. Bariatric surgery in the 1990’s. Swiss Surg 2001;7:11-15 

2.) Gschossmann JM, Holtmann G, Netzer P, Essig M, Balsiger BM, Scheurer U. 

Abdominal pain 

Internist (Berl). 2005 Oct;46(10):1096-104. (IMPF 0.35; 88/105) 

Abstracts, accepted and published 

1.) Balsiger BM, Schilling M, Naef M, Sabbioni M, DeMarco D, Bürgi U, Sterchi A, 

Büchler MW. Vertical Banded Gastroplasty (Mason) as a Surgical Therapy for 

Morbid Obesity. Preliminary Results. Swiss Surg. 1995; Suppl. 2:27 

2.) Balsiger BM, Baer HU, Seiler CA, Feodorovici M, Franz S, Büchler MW. Peritonitis: 

Herdsanierung, ausgedehnte intraoperative Peritoneal-Lavage und direkter 

Abdominalverschluss als Standardtherapie. Swiss Surg. 1996; Suppl. 3:37 

3.) Naef M, Balsiger BM, Baer HU, Sabbioni M, DeMarco D, Bürgi U, Sterchi A, 

Büchler MW. Vertical banded Gastroplasty nach Mason zur chirurgischen Therapie 

morbider Adipositas. Eine prospektive klinische Studie. Akt.Ernaehr.-Med., 

1996; 21:A258 

4.) Shibata C, Balsiger BM, Sarr MG. The extrinsic denervation of small bowel transplantation 

(SBT) induces adrenergic hypersensitivity in ileal but not jejunal smooth 

muscle - at least one interneuron site away from the adrenergic synapse. Gastroenterology, 

1997; 112:A824 

9


5.) Shibata C, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Differing adaptive responses 

of ileal and jejunal smooth muscle to denervation after small bowel transplantation. 

Gastroenterology, 1997; 112:A1473 

6.) Shibata C, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Inhibitory neural 

function in ileal circular smooth muscle after rat small bowel transplantation: Nitric 

oxide has no role. Gastroenterology, 1997; 112:A824 

7.) Balsiger BM, Ohtani N, Shibata C, Murr MM, Anding WJ, Duenes JA, Sarr MG. 

Small bowel transplantation (SBT) alters non-adrenergic non-cholinergic (NANC) 

inhibition in longitudinal smooth muscle of the rat jejunum. Gastroenterology, 

1998; 114: A1377 

8.) Balsiger BM, Ohtani N, Shibata C, Sarr MG. Non-adrenergic non-cholinergic 

(NANC) inhibition in longitudinal smooth muscle of rat jejunum: minor role of nitric 

oxide (NO). Gastroenterology, 1998; 114: A 716 

9.) Murr MM, Balsiger BM, Kennedy FP, Sarr MG. Malabsorbtive procedures for 

severe obesity: comparison of pancreaticobiliary bypass (PBB) and very, very long 

Roux-en-Y gastric bypass (VVLGB). Gastroenterology, 1998; 114: A1412 

10.) Choi MG, Camilleri M, Balsiger BM, Farrugia G. Effect and mechanism of glibenclamide 

on longitudinal smooth muscle contractility in rat colon. Gastroenterology, 

1998; 114: A733 

11.) Luque-de Leon E, Tsiotos G, Balsiger BM, Barnwell J, Burgart L, Sarr MG. Staging 

laparascopy for pancreatic cancer should be used to select the best palliation, 

not to increase resection rate. Gastroenterology, 1998; 114: A1407 

12.) Balsiger BM, Ohtani N, Anding WJ, Duenes JA, Sarr MG. Chronic lack of extrinsic 

neural input increases nitric oxide (NO) independent inhibition after rat small 

bowel transplantation (SBT). Eur Surg Res 1999;31(suppl 1):1 

13.) Balsiger BM, Sarr MG. Roux-en-Y gastric bypass (RYGB) as primary operation 

for morbid obesity at the Mayo clinic. Eur Surg Res 1999;31(suppl 1): 8 



muscles in rats. Gastroenterology, 1999; 116: A1349 

15.) Ohtani N, Balsiger BM, Duenes JA, Sarr MG. Nitric oxide mediates non-adrenergic 

non-cholinergic (NANC) inhibiton in ileal longitudinal smooth muscle of rats. 

Gastroenterology, 1999; 116: A1349 

16.) Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Extrinsic denervation of canine 

jejunum causes neuronal adrenergic and muscular cholinergic hypersensitivity. 


10

PD Dr. med. med. Bruno M. M. Balsiger | Facharzt FMH FMH für Gastroenterologie 

17.) Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Neural inhibition in jejunal circular 

muscle after small bowel transplantation (SBT): nitric oxide (NO) has no apparent 

role. Gastroenterology, 1999; 116: A1349 

18.) Balsiger BM, Murr MM, Sarr MG. Roux-en-Y gastric bypass as a remedial operation 

for gastroesophageal reflux (GER) after vertical banded gastroplasty (VBG). 


19.) Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Adenosine triphosphate (ATP) inhibits 

canine jejunal contractions by neuronal release of nitric oxide (NO). Gastroenterology, 

1999; 116: A1076 

20.) Lee JS, Farrugia G, Balsiger BM, Camilleri M. Glibenclamide protection of colonic 

longitudinal smooth muscle contractile response to hypoxia in rats demaonstrates 

a physiological role of KATP channels. on longitudinal smooth muscle contractility 

in rat colon. Gastroenterology, 1999; 116: A1026 

21.) Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Adrenergic contractile mechanisms 

adapt after chronic extrinsic denervation of the canine small bowel. Gastroenterology, 

2000; 118(4): A2088 

22.) Balsiger BM, Poggio JL, Mai J, Sarr MG. Ten and more years after Vertical banded 

gastroplasty as primary operation for morbid obesity. Gastroenterology, 2000; 

118(4): A3897 

23.) Balsiger BM, Sarr MG, Duenes JA, Anding WJ. Downregulation of nitric oxide dependent 

inhibition in rat jejunum one year after small bowel transplantation (SBT). 

Dig. Surg., 2000: 17: 124 

24.) Balsiger BM, Seiler R, Rickenbacher A, Müller J, Shaw SG: Muscular and neuronal 


Gastroenterology, 2002; 123(1): 1249 

25.) Seiler R, Rickenbacher A, Müller J, Shaw SG, Balsiger BM: Role of α and β 

adrenergic receptor mechanisms in rat jejunal longitudinal muscle contractility. 

Gastroenterology, 2003; 124(1): 1342 

26.) Rickenbacher A, Seiler R, Müller J, Shaw SG, Balsiger BM: Role of β1, β2 and 

β3 receptor contractile mechanisms in adrenergic hypersensitivity after small 

bowel transplantation. Gastroenterology, 2003; 124(1): 1332 

27.) Rickenbacher A, Gallagher SF, Yang J, Balsiger BM, Gower WR, Norman JG, 

Murr MM: Acute pancreatitis induces ileus by upregulating TNF and Nitric Oxide in 

the small intestine. Gastroenterology, 2003; 124(1): 1331 

28.) Haefliger Simon, Seiler R, Rickenbacher A, Shaw SG, Balsiger BM: Differential 

role of nitric oxide in longitudinal and circular muscle of the rat colon. Gastroenterology, 

2005; April suppl. 

11

Book chapters 


1.) Balsiger BM, Seiler CA, Büchler MW. Peritonitis: Herdsanierung und intraoperativ 

extensive Lavage als Standardtherapie. In: Köckerling F, Hohenberger W, Teichmann 

W, eds. Intraabdominelle Infektionen. Heidelberg Leipzig: Barth, 1996 169- 

173 

2.) Sarr MG, Sakorafas GH, Balsiger BM, Farley DR. The spectrum of cystic neoplasms 

of the pancreas. in Dervenis C, ed. Pancreatic tumors: achievements and 

prospective. 2000. Thieme. Stuttgart 

Presentations of papers on meetings and congresses 

1.) Balsiger B.M., Schilling M, Naef M, Sabbioni M, DeMarco D, Bürgi U, Sterchi 

A, Büchler MW. Vertical Banded Gastroplasty (Mason) as a Surgical Therapy for 

Morbid Obesity. Preliminary Results. Swiss association of Surgery: 82. annual 

congress, June 8-10, 1995, Lugano, Switzerland 

2.) Seiler CA, Balsiger BM, Feodorovici M, Büchler MW. Extensive Intraoperative 

Lavage. Abdominal Sepsis: International meeting, September 7-9, 1995, Berne, 

Switzerland 

3.) Büchler MW, Feodorovici M, Balsiger BM. The role of focus elimination: surgery. 

Abdominal Sepsis: International meeting, September 7-9, 1995, Berne, Switzerland 

4.) Balsiger BM, Naef M, Sabbioni M, Läderach K, de Marco D, Bürgi U, Sterchi A, 

Büchler MW. Indication for Vertical Banded Gastroplasty in morbid obesity. Interdisciplinar 

Meeting of Visceral Surgery, February 8, 1996, Berne, Switzerland 

5.) Baer HU, Balsiger BM. Technique and Results of Vertical Banded Gastroplasty 

in morbid obesity. Interdisciplinar Meeting of Visceral Surgery, February 8, 1996, 

Berne, Switzerland 

6.) Balsiger BM, Baer HU, Seiler CA, Feodorovici M, Franz S, Büchler MW. Peritonitis: 

Herdsanierung, ausgedehnte intraoperative Peritoneal-Lavage und direkter Abdominalverschluss 

als Standardtherapie. Swiss association of Surgery: 83 annual 

congress, June 6-8, 1996, Geneva, Switzerland 

7.) Naef M, Balsiger BM, Baer HU, Sabbioni M, DeMarco D, Bürgi U, Sterchi A, 

Büchler MW. Vertical banded Gastroplasty nach Mason zur chirurgischen Therapie 

morbider Adipositas. Eine prospektive klinische Studie. German society of 

research in obesity: 12 annual meeting, October 10 - 12, Wurzburg, Germany 

8.) Shibata C, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Adrenergic denervation 

hypersensitivity in the ileal smooth muscle after small bowel transplantation 

in rats. Minnesota Surgical Society Fall Meeting, November 1, 1996, Minneapolis, 

USA 

12


9.) Luque-de Leon E, Tsiotos G, Balsiger BM, Barnwell J, Burgart L, Sarr MG. 

Should staging laparascopy in pancreatic cancer be aimed at optimizing palliation, 

rather than increasing resectability rate? Minnesota Surgical Society Spring Meeting, 

May 2, 1997, Minneapolis, USA 



oxide has no role. American Gastroenterological Association and American Association 

for the Study of Liver Diseases, May 11 - 14, 1997, Washington D.C. USA 


induces adrenergic hypersensitivity in ileal but not jejunal smooth muscle 

- at least one interneuron site away from the adrenergic synapse. American 

Gastroenterological Association and American Association for the Study of Liver 

Diseases, May 11 - 14, 1997, Washington D.C. USA 

12.) Shibata C, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Differing adaptive 

responses of ileal and jejunal smooth muscle to denervation after small bowel 

transplantation. Society for Surgery of the Alimentary Tract, Annual meeting May 

11 - 14, 1997, Washington D.C. USA 

13.) Luque-de Leon E, Tsiotos G, Balsiger BM, Barnwell J, Burgart L, Sarr MG. 

Should staging laparascopy in pancreatic cancer be aimed at optimizing palliation 

rather than increasing resectability rate? Pancreas Club, May 11, 1997, Washington 

DC, USA 

14.) Balsiger BM, Othani N, Sarr MG. The role of nitric oxide in rat jejunal longitudinal 

smooth muscle. Gut Hormone Symposium, July 25 - July 28, 1997, Florissant, 

Colorado, USA 

15.) Othani N, Balsiger BM, Sarr MG. Technique of studying gut smooth muscle activity 

in vitro. Gut Hormone Symposium, July 25 - 28, 1997, Florissant, Colorado, 

USA 

16.) Balsiger BM, Shibata C, Sarr MG. The extrinsic denervation of small bowel transplantation 

(SBT) induces adrenergic hypersensitivity in ileal but not jejunal smooth 

muscle - at least one interneuron site away from the adrenergic synapse. Minnesota 

Surgical Society Fall Meeting, September 19, 1997, Duluth, Minnesota, 

USA 

17.) Balsiger BM, Othani N, Anding WJ, Duenes JA, Sarr MG. Nitric oxide (NO) inhibits 

rat jejunal longitudinal smooth muscle, but is not major mediator of non-adrenergic 

non-cholinergic (NANC) inhibition. Minnesota Surgical Society Fall Meeting, 

September 19, 1997, Duluth, Minnesota, USA 

18.) Balsiger BM, Othani N, Sarr MG. The role of nitric oxide in rat jejunal longitudinal 

smooth muscle. Midwest Motility Society Meeting, October 2, 1997, Prairie Du 

Chien, Wisconsin, USA 

13


19.) Luque-de Leon E, Tsiotos G, Balsiger BM, Barnwell J, Burgart L, Sarr MG. Optimizacion 

de paliacion en cancer de pancreas mediante laparascopia etapificadora. 

XXI Mexican National Congress of General Surgery, November 3 - 7, 1997, 

Acapulco, Mexico 



oxide has no role. Third annual Balfour surgical research symposium, October 24, 

1997, Rochester, Minnesota, USA 


induces adrenergic hypersensitivity in ileal but not jejunal smooth muscle 

- at least one interneuron site away from the adrenergic synapse. Third annual 

Balfour surgical research symposium, October 24, 1997, Rochester, Minnesota, 

USA 

22.) Shibata C, Balsiger BM, Anding WJ, Duenes JA, Sarr MG. Differing adaptive responses 

of ileal and jejunal smooth muscle to denervation after small bowel transplantation. 

Third annual Balfour surgical research symposium, October 24, 1997, 

Rochester, Minnesota, USA 

23.) Balsiger BM, Othani N, Anding WJ, Duenes JA, Sarr MG. Nitric oxide (NO) and 

non-adrenergic non-cholinergic (NANC) inhibition in longitudinal smooth muscle of 

rat jejunum. 40th Annual University Surgical Residents’ Conference, February 14, 

1998, Milwaukee, Wisconsin, USA 

24.) Balsiger BM, Ohtani N, Shibata C, Murr MM, Anding WJ, Duenes JA, Sarr MG. 

Small bowel transplantation (SBT) alters non-adrenergic non-cholinergic (NANC) 

inhibition in longitudinal smooth muscle of the rat jejunum. Society for Surgery of 

the Alimentary Tract, Annual meeting May 17 - 20, 1998, New Orleans, USA 

25.) Balsiger BM, Ohtani N, Shibata C, Sarr MG. Non-adrenergic non-cholinergic 

(NANC) inhibition in longitudinal smooth muscle of rat jejunum: minor role of nitric 

oxide (NO). American Gastroenterological Association and American Association 

for the Study of Liver Diseases, May 17 - 20, 1998, New Orleans, USA 

26.) Murr MM, Balsiger BM, Kennedy FP, Sarr MG. Malabsorbtive procedures for 

severe obesity: comparison of pancreaticobiliary bypass (PBB) and very, very long 

Roux-en-Y gastric bypass (VVLGB). Society for Surgery of the Alimentary Tract, 

Annual meeting May 17 - 20, 1998, New Orleans, USA 

27.) Luque-de Leon E, Tsiotos G, Balsiger BM, Barnwell J, Burgart L, Sarr MG. Staging 

laparascopy for pancreatic cancer should be used to select the best palliation, 

not to increase resection rate. Society for Surgery of the Alimentary Tract, 

Annual meeting May 17 - 20, 1998, New Orleans, USA 

14


28.) Murr MM, Balsiger BM, Farrugia G, Sarr MG. Role of nitric oxide, VIP and ATP in 

inhibitory neurotransmission in human jejunum. Association of Academic Surgery, 

November 21, 1998, Seattle, USA 

29.) Balsiger BM, Ohtani N, Anding WJ, Duenes JA, Sarr MG. Chronic lack of extrinsic 

neural input increases nitric oxide (NO) independent inhibition after rat small 

bowel transplantation (SBT). European Society for Surgical Research, 34th congress, 

April 22-24, 1999, Bern, Switzerland 

30.) Balsiger BM, Sarr MG. Roux-en-Y gastric bypass (RYGB) as primary operation 

for morbid obesity at the Mayo clinic. European Society for Surgical Research, 

34th congress, April 22-24, 1999, Bern, Switzerland 

31.) Balsiger BM, Murr MM, Sarr MG. Roux-en-Y gastric bypass as a remedial operation 

for gastroesophageal reflux (GER) after vertical banded gastroplasty (VBG). 

Society for Surgery of the Alimentary Tract, Annual meeting May 16 - 19, 1999, 

Orlando, USA 



muscles in rats. Society for Surgery of the Alimentary Tract, Annual meeting May 

16 - 19, 1999, Orlando, USA 

33.) Ohtani N, Balsiger BM, Duenes JA, Sarr MG. Nitric oxide mediates non-adrenergic 

non-cholinergic (NANC) inhibiton in ileal longitudinal smooth muscle of rats. 

American Gastroenterological Association and American Association for the Study 

of Liver Diseases, May 16 - 19, 1999, Orlando, USA 

34.) Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Extrinsic denervation of canine 

jejunum causes neuronal adrenergic and muscular cholinergic hypersensitivity. 

Gastroenterological Association and American Association for the Study of Liver 

Diseases, May 16 - 19, 1999, Orlando, USA 

35.) Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Neural inhibition in jejunal circular 

muscle after small bowel transplantation (SBT): nitric oxide (NO) has no apparent 

role. Society for Surgery of the Alimentary Tract, Annual meeting May 16 - 19, 

1999, Orlando, USA 

36.) Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Adenosine triphosphate (ATP) inhibits 

canine jejunal contractions by neuronal release of nitric oxide (NO). Gastroenterological 

Association and American Association for the Study of Liver Diseases, 

May 16 - 19, 1999, Orlando, USA 

37.) Lee JS, Farrugia G, Balsiger BM, Camilleri M. Glibenclamide protection of colonic 

longitudinal smooth muscle contractile response to hypoxia in rats demaonstrates 

a physiological role of KATP channels. on longitudinal smooth muscle contractility 

in rat colon. Gastroenterological Association and American Association for the 

Study of Liver Diseases, May 16 - 19, 1999, Orlando, USA 

15


38.) Balsiger BM, Duenes JA, Ohtani N, Sarr MG. Adrenergic contractile mechanisms 

adapt after chronic extrinsic denervation of the canine small bowel.: Society for 

Surgery of the Alimentary Tract, Annual meeting May 22 - 24, 2000, San Diego, 

USA 

39.) Balsiger BM, Poggio JL, Mai J, Sarr MG. Ten and more years after Vertical banded 

gastroplasty as primary operation for morbid obesity. Society for Surgery of 

the Alimentary Tract, Annual meeting May 22 - 24, 2000, San Diego, USA 

40.) Balsiger BM, Sarr MG, Duenes JA, Anding WJ. Downregulation of nitric oxide dependent 

inhibition in rat jejunum one year after small bowel transplantation (SBT). 

Int Society of Digestive Surgery, Sept 6-9, 2000 Hamburg, Germany 

41.) Balsiger BM, Seiler R, Rickenbacher A, Müller J, Shaw SG: Muscular and neuronal 


Society for Surgery of the Alimentary Tract, Annual meeting May 19 - 22, 2002, 

San Francisco, USA 

42.) Seiler R, Rickenbacher A, Shaw SG, Balsiger BM: Muscular and neuronal 

adrenergic receptor mechanisms in rat ileal longitudinal muscle contractility. Day 

of clinical research, University of Bern, Nov 13, 2002, Bern, Switzerland 

43.) Seiler R, Rickenbacher A, Müller J, Shaw S.G, Balsiger BM: Role of α and β 

adrenergic receptor mechanisms in rat jejunal longitudinal muscle contractility. 

Society for Surgery of the Alimentary Tract, Annual meeting, May 17 - 22, 2003, 

Orlando, USA 

44.) Rickenbacher A, Seiler R, Müller J, Shaw S.G, Balsiger BM: Role of β1, β2 

and β3 receptor contractile mechanisms in adrenergic hypersensitivity after small 

bowel transplantation. Society for Surgery of the Alimentary Tract, Annual meeting, 


45.) Rickenbacher A, Gallagher SF, Yang J, Balsiger BM, Gower WR, Norman JG, 

Murr MM: Acute pancreatitis induces ileus by upregulating TNF and Nitric Oxide 

in the small intestine. Society for Surgery of the Alimentary Tract, Annual meeting, 


46.) Haefliger Simon, Seiler R, Rickenbacher A, Shaw SG, Balsiger BM: Differential 

role of nitric oxide in longitudinal and circular muscle of the rat colon. Society for 

Surgery of the Alimentary Tract, Annual meeting, May 14 - 18, 2005, Chicago, 

USA 

16


Hepatosplanchnic blood flow distribution and in vitro vascular reactivity during hypoxia and cardiac 

tamponade. José Gorrasi, Francesca Porta, Jukka Takala1, Bruno Balsiger, Sebastian 

Brandt, Lukas Bruegger, Hendrik Bracht, Stephan M. Jakob. Submitted to the European Congress 

of Intensive Care Medicine. Berlin, 2007 

Apparent heterogeneity in splanchnic vascular response to norepinephrine during sepsis. J Gorrasi, 

V Krejci, L Hiltebrand, S Brand, H Bracht, B Balsiger, J Takala, S Jakob. 27th International 

Symposium on Intensive Care and Emergency Medicine. Poster presentation. Brussels, 

Belgium. March 27-30, 2007. 

Apparent heterogenity in splachnic vascular response to norepinephrine during sepsis. J Gorrasi., 

LE Bruegger, S Brandt, H Bracht, B Balsiger, J Takala, SM Jakob. 3rd Swiss Symposium in 

Experimental Surgery. Bern, January 19, 2007 

Video presentations 

1.) Balsiger BM, Baer HU, Büchler MW. Vertical Banded Gastroplasty. Interdisciplinar Meeting of 

Visceral Surgery, February 8, 1996, Berne, Switzerland 

2.) Luque-de Leon E, Balsiger BM, Sarr MG. Transeccion y derivacion gastrica vertical en y- 

Roux en el tratamiento de la obesidad morbida. XXI Mexican National Congress of General 

Surgery, November 3 - 7, 1997, Acapulco, Mexico 

Unpublished work 

1.) Balsiger BM. History of Social Work in the Swiss Cancer Society. Thesis, July 26 1993, Prof. 

Dr. med. U. Boschung, Institute of medical History, Universitiy of Berne 

17

CURRICULUM VITAE Personal details Name: Bruno Markus ...

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