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Annual Report 2003 Aventis - Sanofi

Annual Report 2003 Aventis - Sanofi

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<strong>Aventis</strong> Strategic Brands<br />

Taxotere (docetaxel) is a chemotherapy agent<br />

primarily used to treat metastatic breast cancer<br />

and non-small-cell lung cancer (NSCLC). Launched<br />

in 1995, Taxotere is the foundation of our oncology<br />

franchise and is being studied extensively in earlystage<br />

breast, prostate, head and neck and gastric<br />

cancers.<br />

Approved indications<br />

- Second-line treatment of locally advanced or<br />

metastatic breast cancer and non-small-cell lung<br />

cancer<br />

- First-line treatment of non-small-cell lung cancer<br />

in combination with cisplatin (U.S., Europe, Japan)<br />

- Gastric, ovarian, and head and neck cancer (Japan)<br />

Major markets<br />

Taxotere is marketed in over 86 countries, and is<br />

used widely throughout Europe, the U.S. and Japan.<br />

Product features<br />

- Most widely used taxane in the U.S.<br />

- Only agent approved in Europe for use in combination<br />

with doxorubicin for fi rst-line treatment of<br />

locally advanced or metastatic breast cancer<br />

- Taxotere has demonstrated an impressive tumor<br />

response rate in locally advanced or metastatic<br />

breast cancer after failure of cytotoxic therapy, as<br />

well as prolonged patient survival<br />

- Taxotere was the fi rst taxane approved in the<br />

United States for treatment of locally advanced<br />

or metastatic breast cancer after failure of prior<br />

chemotherapy<br />

- Well-differentiated from paclitaxel<br />

>> 13

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