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Looking Elsewhere and Looking Everywhere (a.k.a. Multiple Testing ...

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Tests Based on Biased Estimators<br />

Let µ <strong>and</strong> K be “smooth” <strong>and</strong> let ˆ λ be a data-tuned balancer of bias &<br />

variance with (ˆλ − λ ∗ )/λ ∗ = OP(T −1/10 ) (λ ∗ the true one). Let ˆQα be<br />

σ K 2 (x)dx<br />

<br />

T ˆλ<br />

⎧<br />

⎛<br />

⎪⎨<br />

−2 log ˆλ + log ⎝ 1<br />

˙K<br />

2π<br />

2 ⎞<br />

(y)dy<br />

⎠ − log<br />

K 2 (y)dy<br />

<br />

−2 log ˆλ<br />

⎪⎩<br />

− log(1−α)<br />

2<br />

⎫<br />

<br />

Then, under {H0 : µ(x) = 0 ∀x ∈ [0, 1]}, <strong>and</strong> ˆbˆ λ (x) = ˆλ 2 1<br />

2 ˆµ′′ (x) K 2dy, P<br />

<br />

<br />

<br />

sup ˆµˆ λ (x) − bˆ λ(x) (x)<br />

x∈[0,1]<br />

<br />

<br />

<br />

> ˆQ1−α<br />

T →∞<br />

−→ α<br />

⎪⎬<br />

.<br />

ˆbˆ λ (x) is a point-wise asymptotic bias correction.<br />

Bonferroni would be conservative, even though failing to account for<br />

bias! (still, this result is asymptotic in T (# of observations))<br />

Victor M. Panaretos (EPFL) Progress on Statistical Issues in Searches SLAC – June 2012 23 / 25<br />

⎪⎭

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