pigmented lesions of oral mucosa.pdf
pigmented lesions of oral mucosa.pdf
pigmented lesions of oral mucosa.pdf
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Management:<br />
No treatment is requied<br />
Nevocellular Nevus and Blue Nevus<br />
ETIOLOGY<br />
nevi are due to benign proliferations <strong>of</strong> melanocytes<br />
There are two major types, based on histology, and these<br />
two types tend to show differences clinically<br />
Nevocellular nevi<br />
arise from basal-layermelanocytes<br />
Since proliferation is minimal, these nevi are macular and<br />
are classified as (junctional nevi)<br />
With time, the melanocytes form clusters<br />
at the epitheliomesenchymal junction and begin to<br />
proliferate (compound nevi)<br />
The second type <strong>of</strong> nevus, not derived from basal-layer<br />
melanocytes, is the blue nevus<br />
neither the ordinary nor the cellular form has the potential<br />
to become a melanoma<br />
Clinical features<br />
both nevocellular and blue nevi tend<br />
to be brown and may be macular or nodular,sharply-defined<br />
border .<br />
Less than 0.5 CM in size<br />
The most common sites : the palate and gingiva but may<br />
also be encountered in the buccal <strong>mucosa</strong> and on the lips.<br />
Diagnosis: Biopsy<br />
Management: Excisional biopsy<br />
Malignant Melanoma<br />
ETIOLOGY<br />
There are no known predisposing factors for intra<strong>oral</strong> melanoma<br />
Mucosal melanomas are extremely rare.
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