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Interventions for treating proximal humeral fractures in adults (Review)

Interventions for treating proximal humeral fractures in adults (Review)

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Zyto 1997 (Cont<strong>in</strong>ued)<br />

Subjective assessment of function <strong>in</strong>clud<strong>in</strong>g ability to carry 5 kg, sleep on <strong>in</strong>jured side, comb hair, per<strong>for</strong>m<br />

personal hygiene<br />

Constant score: overall shoulder function and components (pa<strong>in</strong>, power, range of motion, activities of<br />

daily liv<strong>in</strong>g)<br />

Complications: deep <strong>in</strong>fection, non-union, pulmonary embolism, avascular necrosis of <strong>humeral</strong> head<br />

Mortality<br />

Notes Three patients excluded from 1995 data set (Tornquist 1995) as, on review by Zyto and a radiologist, the<br />

patients did not have 3 or 4 part <strong>fractures</strong> (personal communication).<br />

Zyto’s response to a letter from H. A. Karladani admits that there may have been some <strong>in</strong>accuracy <strong>in</strong> their<br />

classification of the fracture patterns but stressed that the Neer classification system was flawed and that<br />

other factors such as osteoporotic bone need to be considered too.<br />

Risk of bias<br />

Item Authors’ judgement Description<br />

Allocation concealment? Unclear B - Unclear<br />

AO = Arbeitsgeme<strong>in</strong>schaft fur Osteosynthesefragen / Association <strong>for</strong> the Study of Internal Fixation (or ASIF)<br />

AVN = avascular necrosis<br />

A&E = accident and emergency<br />

MI = myocardial <strong>in</strong>farction<br />

PE = pulmonary embolism<br />

Characteristics of excluded studies [ordered by study ID]<br />

Bolano 1995 No <strong>proximal</strong> <strong>humeral</strong> <strong>fractures</strong> <strong>in</strong> randomised trial of <strong>humeral</strong> shaft fracture treatment.<br />

Brownson 2001 This is listed <strong>in</strong> the National Research Register as a multi-centre randomised trial of the management of<br />

displaced surgical neck and displaced shaft <strong>fractures</strong> of the humerus with the Halder <strong>humeral</strong> nail. Contact<br />

with Mr Brownson revealed this to be part of the trial run from Nott<strong>in</strong>gham (see Wallace 2000) which<br />

had been abandoned. Mr Brownson <strong>in</strong>dicated that the very specific <strong>in</strong>clusion criteria (2-part <strong>fractures</strong> with<br />

over 50% displacement) had reduced the potential sample size; patient consent had also been a problem.<br />

Chapman 1997 No <strong>proximal</strong> <strong>humeral</strong> <strong>fractures</strong> <strong>in</strong> randomised trial of <strong>humeral</strong> shaft fracture treatment.<br />

Chiu 1997 No <strong>proximal</strong> <strong>humeral</strong> <strong>fractures</strong> <strong>in</strong> quasi-randomised trial of <strong>humeral</strong> shaft fracture treatment.<br />

de Boer 2003 This is a multi-centre comparative study of locked <strong>in</strong>ternal fixators and non-operative treatment. Not<br />

randomised.<br />

<strong>Interventions</strong> <strong>for</strong> <strong>treat<strong>in</strong>g</strong> <strong>proximal</strong> <strong>humeral</strong> <strong>fractures</strong> <strong>in</strong> <strong>adults</strong> (<strong>Review</strong>)<br />

Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.<br />

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