Subtyping and Surveillance of Salmonellosis in Malaysia.
Subtyping and Surveillance of Salmonellosis in Malaysia.
Subtyping and Surveillance of Salmonellosis in Malaysia.
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Some f<strong>in</strong>d<strong>in</strong>gs<br />
Aprox. Aprox.<br />
115 different XbaI Xba Pulsed-Field Pulsed Field Pr<strong>of</strong>iles (PFPs ( PFPs) ) were observed<br />
among the 300 isolates analyzed (F:0.4-1.0; (F:0.4 1.0; 14-22 14 22 b<strong>and</strong>s; 22-600 22 600 kbp). kbp).<br />
The present observation concurred with the previous report (Thong (Thong<br />
et<br />
al.,JCM 1994) that stra<strong>in</strong>s associated with outbreaks are genetically<br />
more homogeneous as compared with those from sporadic cases <strong>of</strong><br />
typhoid fever.<br />
Each <strong>of</strong> the outbreaks was associated with stra<strong>in</strong>s with 1-3 closely related<br />
pr<strong>of</strong>iles (F:0.74-1.0) while stra<strong>in</strong>s isolated from sporadic cases are more<br />
diverse (F:0.4-1.0)<br />
Six out <strong>of</strong> the 11 outbreaks (between 1987-2003) occurred <strong>in</strong> a northeastern<br />
state <strong>of</strong> <strong>Malaysia</strong>. This area is particularly <strong>in</strong> highly endemic for Salmonella<br />
Typhi.<br />
The exact reasons are not clear. However, the population is generally<br />
poorer. Poor hygiene <strong>and</strong> contam<strong>in</strong>ated foods/water are most probable<br />
reasons.<br />
High population <strong>of</strong> carriers?<br />
Use <strong>of</strong> well water?
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