Anatomy of the Human Excretory System
Anatomy of the Human Excretory System
Anatomy of the Human Excretory System
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<strong>Anatomy</strong> <strong>of</strong> <strong>the</strong> <strong>Human</strong> <strong>Excretory</strong> <strong>System</strong><br />
Fig. 44.18
Glomerular Filtration<br />
Efferent<br />
Arteriole<br />
Glomerulus<br />
Afferent<br />
Arteriole<br />
Podocytes<br />
Bowman’s<br />
Capsule<br />
Blood P – Osmotic P<br />
= Net Filtration Pressure<br />
Peritubular<br />
Capillaries<br />
Proximal<br />
Tubule
The Big Picture<br />
Osmotic Gradient<br />
Medulla<br />
Cortex
Overview <strong>of</strong> Tubular Function<br />
Fig. 44.19
Changes in Osmotic Concentration<br />
Fig. 44.20
Regulation <strong>of</strong> Kidney Function - ADH<br />
Collecting Duct:<br />
↑Permeability<br />
to water<br />
(↑ aquaporins)<br />
Hypothalamus<br />
ADH<br />
↑ Osmolarity<br />
<strong>of</strong> Blood<br />
Alcohol<br />
Thirst
Regulation <strong>of</strong> Kidney Function - RAA Renin<br />
Angiotensin<br />
Aldosterone<br />
Fig.44.21b
Regulation <strong>of</strong> Kidney Function - ANP<br />
Urodilatin<br />
Distal tubule &<br />
Collecting Duct<br />
Urodilatin<br />
↑ Blood Volume<br />
↑ Blood Pressure<br />
Collecting Duct:<br />
↓ NaCl Reabsorption<br />
↓ ADH-stimulated<br />
water reabsorption<br />
Atrial<br />
Natriuretic<br />
Peptide<br />
Atria<br />
in Heart
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