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ii To my wife, Dr. Nah-Young Shin & my son, Edward Won Cho, who ...

ii To my wife, Dr. Nah-Young Shin & my son, Edward Won Cho, who ...

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<strong>To</strong> <strong>my</strong> <strong>wife</strong>, <strong>Dr</strong>. <strong>Nah</strong>-<strong>Young</strong> <strong>Shin</strong> & <strong>my</strong> <strong>son</strong>, <strong>Edward</strong> <strong>Won</strong> <strong>Cho</strong>,<br />

<strong>who</strong> gave me les<strong>son</strong>s of life with smile, crying and love.<br />

<strong>ii</strong>


AKNOWLEDGEMENT<br />

I am deeply thankful to <strong>my</strong> advisor <strong>Dr</strong>. Michael P. Stone for his guidance<br />

with a great patience during this journey. He made me growing through this<br />

voyage. I was affected and encouraged by him. I am also grateful to <strong>my</strong><br />

committee members: <strong>Dr</strong>s. Carmelo J. Rizzo, Terry Lybrand, Sandra J. Rosenthal,<br />

and Chuck Sanders. They supported me with valuable questions and suggestions<br />

in our regular committee meetings. It was <strong>my</strong> honor to have many people <strong>who</strong><br />

helped and taught me through the project. <strong>Dr</strong>s. Thomas and Connie Harris, and<br />

their lab members helped me from the sample preparation and to many<br />

discussions. NMR was the main tool that I used for this journey, and there were<br />

<strong>Dr</strong>. Ja<strong>son</strong> Jacob and Mr. Markus Voehler. They were <strong>my</strong> NMR gurus. I also<br />

would like to thank <strong>Dr</strong>. Hye-<strong>Young</strong> Kim <strong>who</strong> helped me in the beginning in<br />

Stone lab. Another help came from <strong>Dr</strong>. R. Stephen Lloyd and his group members<br />

<strong>who</strong> shared many biological studies about adducts with me and many questions<br />

during our meetings. I enjoyed the time with two senior members in Stone lab:<br />

<strong>Dr</strong>s. Tandace Scholdberg and Keith W. Merrit. They were more than just friends.<br />

I deeply appreciate their good wishes on me. I cannot forget <strong>my</strong> other colleagues<br />

<strong>Dr</strong>s. Kristina Furse and Angela Goodenough for their help and friendship. I also<br />

would like to appreciate <strong>my</strong> lab friends: <strong>Dr</strong>. Feng Wang, Mr. Kyle Brown, <strong>Dr</strong>.<br />

Hai Huang, Ms. Wen Xu, <strong>Dr</strong>. Ganesh Shanmugam, <strong>Dr</strong>. Yazhen Wang, Ms.<br />

Heather Day and Ms. Sarrah Musser <strong>who</strong> provided me a cozy lab environment<br />

with their pleasant smiles. Especially, Sarrah helped me for proofreading this<br />

dissertation. There were Korean friends <strong>who</strong> were with me during this journey.<br />

<strong>Dr</strong>. <strong>Young</strong>-Tae Lee was a special friend <strong>who</strong>m I met here. Along with <strong>Dr</strong>. Hak-<br />

<strong>ii</strong>i


Jun Kim, we played tennis together and loved NMR. I was fortunate to have our<br />

neighbors, <strong>Dr</strong>. Ji-Woong Han and Ms. Iran No. <strong>Dr</strong>-to-be Min-Suk Kang became<br />

one of beloved friends while we were sharing graduate life. <strong>Dr</strong>s. James McAfee<br />

and Iren Zegar were the people <strong>who</strong> encouraged me to start this journey from<br />

Pittsburg to here. And, <strong>my</strong> special thanks to <strong>Dr</strong>. Robert E. Venturella (<strong>Dr</strong>. Bob)<br />

should be addressed. He is <strong>my</strong> supporter and kept encouraging me from the<br />

beginning. Without his encouragement, it was impossible for such a shy Korean<br />

came to USA for doing his study.<br />

My Nashville life was joyful. When we were suffered, there was a shelter,<br />

NKP church. It was good to have good people around us. I apologize if I missed<br />

anyone to express <strong>my</strong> thanks on this page.<br />

Needless to say, <strong>my</strong> Ph. D could not be achieved without sacrifice of many<br />

people. I am so much in debt to <strong>my</strong> family: <strong>my</strong> parents, parents-in-laws, brother,<br />

brother-in-law, sister-in-law, grandmother, and late grandfather. They were<br />

always in <strong>my</strong> heart and made me strong. Especially, I wish to thank <strong>my</strong> <strong>wife</strong>,<br />

<strong>Nah</strong>-<strong>Young</strong> <strong>Shin</strong> and <strong>my</strong> <strong>son</strong>, <strong>Edward</strong> (<strong>Won</strong>). They joined <strong>my</strong> journey and they<br />

were always with me. They helped and feeded me so much with great loves. I<br />

hope that this journey was worthy of their sacrifice for me.<br />

And finally, I thank God.<br />

iv

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