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Publication Ref No.: <strong>IJPRD</strong>/2009/PUB/ARTI/VOL-8/OCT/008 ISSN 0974 – 9446<br />

(SURVEY ARTICLE)<br />

ETHNO-MEDICO BOTANY OF MEDICINAL PLANTS FOR THE TREATMENT OF DIABETIC<br />

ACTIVITY IN KRISHNA DISTRICT, ANDHRA PRADESH<br />

Phani Ratna Prasanth .G * , Ashok Kumar.D<br />

Department <strong>of</strong> Pharmacognosy and Phytochemistry,<br />

Dr.H.L.Thimme Gowda College <strong>of</strong> Pharmacy, Kengal, Channapatna, Ramanagaram District, Karnataka –<br />

571502.<br />

ABSTRACT<br />

Around 70% <strong>of</strong> population in India relies on <strong>the</strong>se systems <strong>for</strong> primary health care. Ayurveda and Indian<br />

System <strong>of</strong> Medicine (ISM) utilize a vast number <strong>of</strong> <strong>plants</strong>. The traditional Indian system <strong>of</strong> medicine<br />

includes many natural <strong>plants</strong> used <strong>for</strong> <strong>the</strong> treatment <strong>of</strong> diabetic activity. In <strong>the</strong> present study, <strong>the</strong> herbal<br />

remedies used <strong>for</strong> diabetic treatment in Krishna district, which is located in coastal region <strong>of</strong> Andhra<br />

Pradesh, India are discussed. A total number <strong>of</strong> around twenty-five <strong>plants</strong> such as Eugenia jambolana,<br />

Ocimum sanctum, Phyllanthus amarus, Pterocarpus marsupium, Tinospora cordifolia, Curcuma longa<br />

and Trigonella foenum graecum etc. from various families used <strong>the</strong>rapeutically against diabetes and<br />

related disorders are being covered, which includes Biological source, family, parts <strong>of</strong> <strong>the</strong> plant used,<br />

regional name, local use and <strong>the</strong>rapeutic action (traditional use) <strong>for</strong> all <strong>the</strong> natural <strong>plants</strong>. This detailed<br />

in<strong>for</strong>mation will be helpful <strong>for</strong> <strong>the</strong> pharmacognosist, botanist, phytochemist and pharmacologist <strong>for</strong> <strong>the</strong><br />

collection and identification <strong>of</strong> <strong>the</strong> plant <strong>for</strong> <strong>the</strong>ir research work.<br />

Key words: <strong>Ethno</strong>-<strong>medico</strong> <strong>botany</strong>, Herbal drugs, Anti-diabetic, Krishna district<br />

International Journal <strong>of</strong> Pharma Research and Development – Online<br />

www.ijprd.com<br />

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Publication Ref No.: <strong>IJPRD</strong>/2009/PUB/ARTI/VOL-8/OCT/008 ISSN 0974 – 9446<br />

INTRODUCTION AND MATERIALS AND METHODS<br />

INTRODUCTION<br />

The art <strong>of</strong> herbal treatment has very deep roots in Indian culture. Even today in most <strong>of</strong> <strong>the</strong> rural areas<br />

people are depending on herbal drug systems <strong>for</strong> primary health care. The present paper deals with <strong>the</strong><br />

first hand in<strong>for</strong>mation <strong>of</strong> <strong>the</strong> traditional <strong>medicinal</strong> claims referring to treat diabetes in <strong>the</strong> district <strong>of</strong> Krishna<br />

in Andhra Pradesh. So far no systematic medical ethno survey has been made in this area. The goal <strong>of</strong><br />

this ethno <strong>medico</strong> botanical survey is to ga<strong>the</strong>r in<strong>for</strong>mation on Biological source, family, parts <strong>of</strong> <strong>the</strong> plant<br />

used, regional name, local use and <strong>the</strong>rapeutic uses (traditional use) along with chemical constituents<br />

and such survey is to know about <strong>the</strong> use <strong>of</strong> drugs from natural <strong>medicinal</strong> <strong>plants</strong> <strong>for</strong> <strong>the</strong> treatment <strong>of</strong><br />

Diabetes.<br />

MATERIALS AND METHODS<br />

Study Area<br />

Krishna district is one <strong>of</strong> <strong>the</strong> 23 districts in <strong>the</strong> state and one <strong>of</strong> <strong>the</strong> nine districts in <strong>the</strong> costal region <strong>of</strong><br />

state Andhra Pradesh located in central area <strong>of</strong> this region. The elevation above <strong>the</strong> mean sea level<br />

ranges from 45 mts. The climate is tropical with three different seasons in a year such as summer<br />

(march-mid June), rainy (mid June- Sep), winter (Oct – Feb). October and March constitute that transition<br />

months between <strong>the</strong> rainy and winter seasons and winter and summer seasons respectively.<br />

International Journal <strong>of</strong> Pharma Research and Development – Online<br />

www.ijprd.com<br />

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Publication Ref No.: <strong>IJPRD</strong>/2009/PUB/ARTI/VOL-8/OCT/008 ISSN 0974 – 9446<br />

Fig. 1 & 2: Krishna District <strong>of</strong> Andhra Pradesh<br />

The present study is based on <strong>the</strong> intensive field <strong>of</strong> <strong>the</strong> area during <strong>the</strong> period <strong>of</strong> Feb-July 2008. Regular<br />

field studies were made in <strong>the</strong> study area during <strong>the</strong> period. The in<strong>for</strong>mation about <strong>the</strong> <strong>plants</strong> used <strong>for</strong><br />

diabetes was ga<strong>the</strong>red through interviews and discussion with <strong>the</strong> elderly people and traditional medical<br />

practitioners were also consulted. Herbal <strong>plants</strong> referred by <strong>the</strong>se people were au<strong>the</strong>ntically identified<br />

with <strong>the</strong> help <strong>of</strong> pharmacognosist and botanist (Fig 1 & 2).<br />

RESULTS<br />

All toge<strong>the</strong>r <strong>plants</strong> belonging to different families have been documented <strong>for</strong> <strong>the</strong>ir <strong>the</strong>rapeutic properties<br />

and diabetes. The collected in<strong>for</strong>mation’s are arranged in <strong>the</strong> alphabetic order <strong>of</strong> <strong>the</strong> plant botanical<br />

name with <strong>the</strong> local (or) common name, vernacular names, parts used, local use, active constituents and<br />

<strong>the</strong>rapeutic action <strong>for</strong> each plant 1, 2, 3, and 4 (Table I).<br />

DISCUSSION<br />

Among <strong>the</strong> <strong>plants</strong> used <strong>for</strong> <strong>the</strong> diabetes, “Eugenia jambolana, Curcuma longa and Trigonella foenum<br />

graecum” seems to be most common <strong>plants</strong> used to treat diabetes and is available everywhere. Along<br />

with <strong>the</strong>se Triphala and Momordica charantia listed which are <strong>the</strong> major traditional drugs <strong>for</strong> treating this<br />

diseases. The detailed natural <strong>plants</strong> not only used <strong>for</strong> <strong>the</strong> treatment <strong>of</strong> diabetes but also treated <strong>for</strong> o<strong>the</strong>r<br />

ailments also. The in<strong>for</strong>mation collected from <strong>the</strong> people <strong>of</strong> that area was reexamined by consulting<br />

important works pertaining to Indian Medicinal <strong>plants</strong> and <strong>Ethno</strong><strong>botany</strong> such as Wealth <strong>of</strong> India<br />

(Anonymous, 1992), Indian Medicinal Plants (Kithikar and Basu, 1975), Indian Material Medica<br />

(Nadkarni, 2002) and Indigenous Drugs <strong>of</strong> India (Dey, 1973) 5,6,7,8 .<br />

CONCLUSION<br />

The claims emanating from <strong>the</strong> present survey need to be subjected to pharmacochemical studies in<br />

order to discover <strong>the</strong>ir true potential, as it is very difficult to judge <strong>the</strong> effectiveness <strong>of</strong> herbal medicine.<br />

The main purpose is not to prescribe any remedies <strong>for</strong> any <strong>of</strong> <strong>the</strong> diseases but to document <strong>the</strong> uses and<br />

draw <strong>the</strong> attention <strong>of</strong> pharmacognosist, botanist, phytochemist and pharmacologist <strong>for</strong> fur<strong>the</strong>r scientific<br />

research in this area.<br />

International Journal <strong>of</strong> Pharma Research and Development – Online<br />

www.ijprd.com<br />

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Publication Ref No.: <strong>IJPRD</strong>/2009/PUB/ARTI/VOL-8/OCT/008 ISSN 0974 – 9446<br />

S. No Biological<br />

Source<br />

01 Abroma<br />

augusta<br />

(Sterculiaceae)<br />

02 Aconitum ferox<br />

(Ranunculaceae)<br />

03 Andrographis<br />

paniculata<br />

(Acanthaceae)<br />

04 Cassia auriculata<br />

(Caesalpiniaceae<br />

)<br />

05 Cassia fistula<br />

(Cagesalpiniacea<br />

e)<br />

06 Cassia sophora<br />

(Caesalpiniaceae<br />

)<br />

Table 1: List <strong>of</strong> <strong>medicinal</strong> <strong>plants</strong> used <strong>for</strong> <strong>the</strong> treatment <strong>of</strong> Diabetic activity<br />

Common Local Part Used Active<br />

Name Name<br />

Constituents<br />

Devils cotton Perita Root, Root Alkaloids,<br />

bark,<br />

Stems,<br />

Leaves<br />

Fixed oil<br />

Bachnag Vasanubhi Tuberous Alkaloidsroot<br />

Hampnapelline,<br />

Napelline<br />

Kalmegh<br />

Tanner’s<br />

cassia<br />

Purging<br />

cassia<br />

Senna<br />

purpurea<br />

Nelavemu<br />

Dried or<br />

fresh entire<br />

aerial part<br />

Tangedu Roots,<br />

Barks,<br />

Leaves,<br />

Flowers,<br />

Seeds<br />

Kondrakaya Pulp, Root<br />

bark, Roots,<br />

Flowers,<br />

Pods,<br />

Paidi<br />

tangedu<br />

Leaves<br />

Bark,<br />

Leaves,<br />

Seeds,<br />

Root, Root<br />

Bitter<br />

principles-<br />

Andrographolid<br />

e Flavonoids-<br />

Echidinin<br />

Emodin,<br />

Rubiadin<br />

Glutin, Rhein,<br />

Glucoside-<br />

Barbaloin,<br />

Phlobaphenes<br />

Emodin,<br />

Chrysophanic<br />

acid<br />

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Local Use Therapeutic<br />

Action<br />

Uterine tonic, Demulcent,<br />

Dysmenorrhoe Emmenagogue<br />

a<br />

Decreasing<br />

quantity <strong>of</strong><br />

urine and sugar<br />

Stomachic,<br />

An<strong>the</strong>lmentic<br />

Antidiabetic,<br />

Paralyses <strong>the</strong><br />

respiratory<br />

center<br />

Febrifuge,<br />

Chologogue.<br />

Chylous urine Diabetes,<br />

Purulent<br />

opthalmia<br />

Fever,<br />

Diseases <strong>of</strong><br />

heart,<br />

Antidiabetic,<br />

Mild Laxative<br />

Diabetes,<br />

diminishes<br />

urine<br />

Root-Tonic,<br />

Febrifuge, Fruit-<br />

Cathartic<br />

Cathartic,<br />

Expectorant.<br />

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Publication Ref No.: <strong>IJPRD</strong>/2009/PUB/ARTI/VOL-8/OCT/008 ISSN 0974 – 9446<br />

07 Cephalandra<br />

indica<br />

(Cucurbitaceae)<br />

08 Citrus aurantum<br />

(Rutaceae)<br />

09 Cocculs cardifolia<br />

(Menispermacea<br />

e)<br />

10 Cocculus villosus<br />

(Menispermacea<br />

e)<br />

11 Curcuma longa<br />

(Zingiberaceae)<br />

12 Emblica<br />

<strong>of</strong>ficinalis<br />

(Euphorbiaceae)<br />

13 Eriodendron<br />

anfractuosum<br />

(Bombaceae)<br />

Vimbaja<br />

Common<br />

orange<br />

Dondatiga<br />

bark<br />

Leaves,<br />

Root, Fruit,<br />

Bark<br />

Gaja nimma Fresh and<br />

Outer parts<br />

<strong>of</strong> Pericarp,<br />

Flowers<br />

Guduchi Tippatego Stem,<br />

Leaves,<br />

Roots,<br />

Fecula<br />

Jamtike Chipurutige Root,<br />

Leaves<br />

Turmeric Pasupu Tubers and<br />

Rhizomes<br />

Indian goose<br />

berry,<br />

Amla<br />

White silk<br />

cotton tree<br />

Usirikaya,<br />

Usiri<br />

Buruyasaun<br />

a<br />

Fruit, Seed<br />

(or) Nut,<br />

Leaf, Bark,<br />

Flowers<br />

Gum,<br />

Unripe<br />

Fruits,<br />

Seeds,<br />

Flowers<br />

Roots,<br />

Resins,<br />

Alkaloids<br />

3 Glycosides-<br />

Hesperidin,<br />

Aurantiamarin<br />

Berberine,<br />

Sesquiterpene<br />

Resins,<br />

Alkaloids<br />

Curcuminoids,<br />

Desmethoxy<br />

curcumin<br />

Niacin,<br />

Embellic acid,<br />

Triglycerides <strong>of</strong><br />

Oleic acid,<br />

Linoleic acids.<br />

Gallic acids<br />

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Diabetics,<br />

Glycosuria,<br />

Skin diseases<br />

Diabetics,<br />

Blood purifier<br />

Acidity <strong>of</strong> urine<br />

and Urinary<br />

diseases<br />

Billous<br />

dyspepsia,<br />

Fever<br />

Aromatics<br />

Coloring agent,<br />

Ointment,<br />

Creams<br />

Anaemia,<br />

Jaundice,<br />

Dyspepsia<br />

Diabetes,<br />

Styptic in<br />

Diarrohea and<br />

Dysentry<br />

Antispasmodic,<br />

Glucokeninreduces<br />

sugar in<br />

blood<br />

Stomachic,<br />

Tonic,<br />

Astringent,<br />

Antispasmodic,<br />

Anodyne<br />

Bitter tonic,<br />

Aphrodisiac,<br />

Hepatic stimulant<br />

Root-Bitter,<br />

Acrid, Anti<br />

periodic, Tonic<br />

Antiarthritic,<br />

Antilipidemic<br />

Fruit-Sour and<br />

Astringent,<br />

Flowers-Cooling<br />

Dried Juice-<br />

Aphrodisiac and<br />

laxative and<br />

Unripe fruitdemulcent<br />

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Publication Ref No.: <strong>IJPRD</strong>/2009/PUB/ARTI/VOL-8/OCT/008 ISSN 0974 – 9446<br />

14 Eugenia<br />

jambolana<br />

(Myrtaceae)<br />

15 Gymnema<br />

sylvestre<br />

(Asclepiadaceae)<br />

16 Lodoicea<br />

sechellarsum<br />

(Arecaceae)<br />

17 Momordica<br />

charantia<br />

(Cucurbitaceae)<br />

18 Ocimum sanctum<br />

(Labiate)<br />

19 Phyllanthus niruri<br />

(Euphorbiaceae)<br />

20 Pterocarpus<br />

marsupium<br />

(Papilionaceae)<br />

Black plum,<br />

Black berry<br />

Naeraedu,<br />

Racha<br />

naeredu<br />

Wood Podapathri,<br />

Putla, Podra<br />

Sea coconut Samudrapu<br />

tenkaya<br />

Bitter gourd<br />

Tulasi<br />

Jaramala<br />

niruri<br />

Indian kino<br />

tree<br />

Kakara Fruits,<br />

Seeds,<br />

Leaves<br />

Krushna<br />

tulasi<br />

Nela usirika<br />

Peddagi<br />

Leaves<br />

Fruit, Ellagic acid, Diabetes,<br />

Leaves, Albumen Diminishes<br />

Dried<br />

quantity <strong>of</strong><br />

seeds, Bark<br />

Urine<br />

Whole plant Gymnemosides Antidiabetic<br />

1-7,gymnemic drug, Sugar<br />

acid,<br />

destroying<br />

Triacotane agent<br />

Fruit (or)<br />

- Decreases<br />

Nut<br />

Sugar in Urine<br />

in Diabetes<br />

mellitus<br />

Leaves,<br />

Seed, Root<br />

Whole plant<br />

Heartwood,<br />

Leaves,<br />

Flower,<br />

Gum<br />

Alkaloids,<br />

Steroidal<br />

saponin-<br />

Charantin<br />

Essential oil-<br />

Eugenol,<br />

Caryophylline<br />

Bitter<br />

substance-<br />

Phyllanthin<br />

1-Epicatechin,<br />

Fixed oils-<br />

Liquiritigenin,<br />

Catechol<br />

Gout,<br />

Rheumatism,<br />

Leprosy<br />

Hypoglycemic<br />

effect<br />

Jaundice,<br />

Diabetics,<br />

Dysentery<br />

Diabetic,<br />

An<strong>the</strong>lmentic<br />

properties,<br />

Diarrhoea<br />

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Astringent,<br />

Diuretic,<br />

Antidiabetic<br />

Suppress blood<br />

glucose level<br />

Treatment <strong>for</strong><br />

diabetic activity<br />

Leaves-<br />

Galactagogue,<br />

Anti bilious<br />

Demulcent,<br />

Expectorant,<br />

Febrifuge<br />

De-obstruent,<br />

Diuretic,<br />

Astringent<br />

Astringent<br />

6


Publication Ref No.: <strong>IJPRD</strong>/2009/PUB/ARTI/VOL-8/OCT/008 ISSN 0974 – 9446<br />

21 Rubia cardifolia<br />

(Rubiaceae)<br />

22 Terminalia bellirica<br />

(Combretaceae)<br />

23 Terminalia chebula<br />

(Combretaceae)<br />

24 Tinospora cordifolia<br />

(Menispermeaceae<br />

)<br />

25 Trigonella foenum<br />

graeceum<br />

(Papilionaceae)<br />

Indian<br />

madder,<br />

Dyer madder<br />

Belliric<br />

myrobalan<br />

Chebulic<br />

myrobalan,<br />

Harras<br />

Tamravalli Roots<br />

Akkam,<br />

Thani,<br />

Vibhitkamu<br />

Gilo, Guduchi Tippatago,<br />

Guduchi<br />

Karakkaya Dried<br />

mature and<br />

immature<br />

fruits<br />

Resins,<br />

Extractive<br />

matter, Gum<br />

Fruits Ellagic acid,<br />

Chebulagic<br />

acid<br />

Fixed oils-<br />

Stem and<br />

Root<br />

Fenu greek Menthulu Seeds,<br />

Pods and<br />

Leaves<br />

Palmitic acid<br />

Tannins,<br />

Pyrogallol type-<br />

Chebulinic<br />

acid, Chebulic<br />

acid<br />

Alkaloids-<br />

Berberine,<br />

Sesquiterpenetinocordifolin<br />

Albuminoids,<br />

Saponins,<br />

Globulins<br />

Dropsy,<br />

Paralysis,<br />

Jaundice<br />

Reduces sugar<br />

in blood, Tonic,<br />

Diarrhoea<br />

Chronic ulcers,<br />

Gargle in<br />

Stomatitis<br />

Dyspepsia,<br />

Debilitating<br />

diseases,<br />

Intermittent<br />

fever<br />

Dysentery,<br />

Diarrhoea,<br />

Flatulence<br />

International Journal <strong>of</strong> Pharma Research and Development – Online<br />

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Emmenagogue,<br />

Astringent,<br />

Diuretic<br />

Astringent,<br />

Antiseptic,<br />

Dysentery,<br />

Anti diabetic<br />

Astringent,<br />

Purgative,<br />

Alterative,<br />

Laxative<br />

Immunomodulato<br />

r<br />

Hepatoprotective<br />

Mucilaginous,<br />

Demulcent,<br />

Emmenagogue<br />

7


Publication Ref No.: <strong>IJPRD</strong>/2009/PUB/ARTI/VOL-8/OCT/008 ISSN 0974 – 9446<br />

International Journal <strong>of</strong> Pharma Research and Development – Online<br />

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Publication Ref No.: <strong>IJPRD</strong>/2009/PUB/ARTI/VOL-8/OCT/008 ISSN 0974 – 9446<br />

ACKNOWLEDGEMENT<br />

The Authors are thankful to <strong>the</strong> management and staff <strong>of</strong> Dr.H.L.T.College <strong>of</strong> Pharmacy <strong>for</strong> providing <strong>the</strong><br />

financial assistance. Acknowledgement is fur<strong>the</strong>r extended to Traditional medical practitioners, Ayurvedic<br />

doctors and elder people <strong>of</strong> Krishna district, Andhra Pradesh <strong>for</strong> exchanging <strong>the</strong>ir valuable in<strong>for</strong>mation<br />

REFERENCES<br />

1. Jain SK. Medicinal <strong>plants</strong>, National Book Trust, New Delhi, 2001, pp. 23-182.<br />

2. Agarwal SS, Tamrakar BP, Paridhavi M. Clinically Useful Herbal Drugs, I st Edition, Ahuja Publishing<br />

House, Delhi, 2005, pp. 27-300.<br />

3. Agarwal SS, Paridhavi M.Herbal Drug Technology, I st Edition, University Press, Hyderabad, pp. 69,<br />

90,104,106.<br />

4. Anonymous, Quality Standards <strong>of</strong> Indian Medicinal Plants, Volume I, Indian Council <strong>of</strong> Medical<br />

Research, New Delhi, 2003, pp. 102-212.<br />

5. Anonymous, Wealth <strong>of</strong> India, Raw Materials, 1992, Volume I-X, Council <strong>of</strong> Scientific and Industrial<br />

Research, New Delhi, pp. 54-87, 435-672, 1098-1349.<br />

6. Kirthikar KR, Basu BP, Indian Medicinal Plants, Volume I-IV, Periodical Experts, New Delhi, 1975, pp.<br />

52-65, 234-422, 1077-1687.<br />

7. Nadkarni KM. Indian Materia Medica, Volume I, Popular Prakashan, Mumbai, 2002, pp. 4-5,23-25,<br />

101-103, 284-749, 1001-1243.<br />

8. Dey KL, The Indigenous Drugs <strong>of</strong> India, The Chronia Botanica, New Delhi, 1973, pp. 24-38, 167-338,<br />

543-624.<br />

International Journal <strong>of</strong> Pharma Research and Development – Online<br />

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