CURRICULUM VITAE Part I General Information DATE PREPARED ...
CURRICULUM VITAE Part I General Information DATE PREPARED ...
CURRICULUM VITAE Part I General Information DATE PREPARED ...
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2003 Scientific Reviewer, Cell Biology Review Panel #1, Department of<br />
Defense Prostate Cancer Research Program<br />
2004- 2005 Scientific Reviewer, Pathobiology Review Panel #3, Department of<br />
Defense Prostate Cancer Research Program<br />
2006- Scientific Reviewer, Pathobiology Review Panel #2, Department of<br />
Defense Prostate Cancer Research Program<br />
Community Service Related to Professional Work:<br />
2006; 2010 Mentor, DF/HCC Continuing Umbrella of Research Experiences<br />
(CURE) Program<br />
2007- 2009<br />
Editorial activities:<br />
Mentor, <strong>Part</strong>ners Student Success Jobs Program, Brigham and<br />
Women’s Hospital<br />
2004- Ad hoc reviewer:<br />
American Journal of Pathology, American Journal of Physiology,<br />
Breast Cancer Research, British Journal of Cancer, BJU International,<br />
Cancer, Cancer Research, Clinical Cancer Research, Development,<br />
Developmental Biology, Diagnostic Molecular Pathology, Human<br />
Pathology, International Journal of Cancer, Journal of Urology,<br />
Laboratory Investigation, Lancet Oncology, Nature Medicine, PLoS<br />
ONE<br />
2008-<br />
Awards and Honors:<br />
Member, Editorial Board:<br />
Clinical Cancer Research<br />
Diagnostic Molecular Pathology<br />
1988 M.D, summa cum laude, University of Rome<br />
1998 The Daland Award, The New England Cancer Society, Worcester, MA<br />
2001 Hershey Young Investigator Award, Boston MA<br />
2002 CaP CURE Award<br />
2007 <strong>Part</strong>ners in Excellence Award, Student Success Jobs Program Mentor<br />
<strong>Part</strong> II Research, Teaching, and Clinical Contribution<br />
A. Narrative Report:<br />
Research contributions: My research is focused on genitourinary malignancies, including<br />
prostate, bladder and renal cancer.<br />
Defining the cell(s) of origin of tumors is fundamental to elucidate the molecular mechanisms<br />
involved in their pathogenesis. A major limitation for the identification of the cell type(s)<br />
involved in the initiation and propagation of prostate and bladder cancers is that the identity of<br />
stem cells and differentiation programs in these epithelia remains unclear. My research aims to<br />
identify cell lineages in the prostate and bladder urothelium. I have previously demonstrated that<br />
p63 is selectively expressed in basal cells of the prostate and urothelium and that p63-deficient<br />
mice present defects in the development of these tissues. My subsequent studies have shown that<br />
the early developing prostate (prostate buds) consists exclusively of p63-positive basal cells,<br />
3
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