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2010 (PDF) - The College of Veterinary Medicine at Cornell University

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Program Scholars<br />

& their Research<br />

Emily Ames, <strong>University</strong> <strong>of</strong> Calgary, Reproductive Biology<br />

Characteriz<strong>at</strong>ion <strong>of</strong> MATER Expression in Feline Oocytes<br />

I applied to the Leadership Program while in my second year <strong>at</strong> UCVM in<br />

order to broaden my understanding <strong>of</strong> non-traditional careers available to<br />

veterinarians. I have been involved in veterinary clinical practice from a<br />

young age and still gre<strong>at</strong>ly enjoy it. However, I have increasingly become<br />

fascin<strong>at</strong>ed by the how’s and why’s <strong>of</strong> the process, diagnosis and tre<strong>at</strong>ment<br />

<strong>of</strong> animal diseases and production challenges. My experiences this summer<br />

have truly opened my eyes to the numerous ways I can expand on these<br />

interests throughout my career while contributing directly or indirectly to<br />

clinical practice. I am considering the numerous options available to me after<br />

gradu<strong>at</strong>ion with enthusiasm and will likely pursue an internship as a fi rst step<br />

toward my career goal.<br />

My summer research project was focused on the study <strong>of</strong> MATER in feline<br />

oocytes. MATER or M<strong>at</strong>ernal Antigen Th<strong>at</strong> Embryos Require is a m<strong>at</strong>ernal<br />

effect gene with an expression th<strong>at</strong> is thought to be restricted to oocytes<br />

and early embryos. It was fi rst identifi ed as an antigen associ<strong>at</strong>ed with a mouse model <strong>of</strong> autoimmune oophoritis<br />

resulting in permanent sterility. <strong>The</strong> Coonrod lab is studying MATER as a potential immunogen in order to produce a<br />

permanent vaccine immunosterilant for female c<strong>at</strong>s. My project involved characterizing the loc<strong>at</strong>ion <strong>of</strong> MATER DNA<br />

transcription and proteins in feline reproductive tissues and oocytes.<br />

I would like to extend a heartfelt thanks to Dr. Scott Coonrod and all the fantastic people working in his labor<strong>at</strong>ory,<br />

especially Boram Kim. I would also like to thank Drs. McGregor and Fraser for making this program possible and<br />

facilit<strong>at</strong>ing an unforgettable summer.<br />

To prepare tomorrow’s scientists and public health pr<strong>of</strong>essionals<br />

23

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